Consultation: I was because of repeated miscarriages before, my husband took me to the hospital to check it out, the doctor said that I have a chromosomal balance translocation, I must do three generations of IVF, I just failed the first IVF transplant, but I have not yet found out the cause, what are the reasons for the failure of the three-generation IVF transplant? What tests do I need to do?
Fertility: The third generation of IVF is a kind of assisted reproductive technology that comes into being for chromosomal abnormalities in both men and women, usually before transfer, the embryo is analyzed for genetic material to determine whether there is a chromosomal problem and avoid the transmission of genetic diseases. However, the third-generation test tube, like the first-generation second-generation test tube, has a very low transplant success rate, which leads to many reasons for the failure of the third-generation test tube transplant.
Reasons for failure of three-generation IVF transplantation
1. Poor embryonic development potential, if the quality of the man's sperm or the woman's egg itself is not good, then even if the sperm and egg are combined to develop into an embryo, its development potential is relatively poor, which will greatly reduce the success rate of the transfer;
2. Endometrial acceptance decreases, and the requirement for embryo transfer for endometrium is more than 8 mm. Many patients have a thin intima because they have had a miscarriage or curettage before, so the possibility of successful transplantation will be greatly reduced;
3. Uterine lesions, usually repeated transplant failures can be due to the possibility of polyps, uterine cavity adhesions, and adenomyosis in the uterus, which will reduce the chance of implantation of the embryo.
In general, there are many reasons for the failure of the third-generation IVF transplant, and it is recommended to go to the hospital for a systematic examination, try to exclude lesions, and increase the chance of success next time.