The emergence of IVF technology has helped many infertile families realize their dreams of having a baby, but although this technology has been effective in the treatment of infertility, it is not currently guaranteed to be 100% successful, and not all women who do IVF can succeed at once, because there are many factors that affect its success rate, such as hospital choice, doctor's technical level and the patient's age, physical health, psychological factors, and so on. So, how do various factors affect the success rate of test tubes? The following is a detailed introduction to this from Hengjian Overseas.
1. Endometrial receptivity problems
Endometrial receptivity is the receptivity of the endometrium to the embryo. The successful establishment of endometrial receptivity in the embryo implantation process is an indispensable factor to ensure the successful implantation of embryos, and there are currently no good indicators to assess endometrial receptivity.
At present, the commonly used clinical evaluation index of the intima is the morphological evaluation of the intima under the vaginaL ultrasound, and the endometrium under the B ultrasound is divided into three types: type A: the intimal three-line signs are clear; Type B: the three-line sign is blurred and visible; Type C: The three-line sign disappears.
Preoperative hysteroscopy can also exclude abnormal endometrial lesions.
If patients with high embryo quality are not able to have a successful pregnancy after transfer, hysteroscopy is recommended for this part of the patient to exclude uterine lesions.
2. Embryo quality
At present, the evaluation of embryo quality is mainly carried out by observing the morphology and development rate of embryos, which are simple and easy to perform and non-destructive. However, it is difficult to accurately predict the developmental potential of embryos, with an accuracy of about 60-70%.
It is generally believed that 66-48 hours after insemination, development to the 6-8 cell stage is the normal development rate of the embryo. Before transferring embryos, consider the quality of the embryos and select embryos with high developmental potential for transfer, but limit the number of transferred embryos to avoid multiple births.
Improving the quality of the embryo starts with improving the quality of the egg and the egg, conditioning the body of both parties is fundamental, having a good diet and living habits, and the necessary nutritional supplements to enhance fertility.
3. Physical condition and psychological state
Severe psychological stress can affect endocrine levels and therefore IVF success rates. Psychological stress often makes women nervous, causing uterine muscle contraction disorders, causing embryos to implant normally, resulting in IVF embryo transfer failure.
4. Endometrial environment
Since the embryo implants in the endometrium, endometrial damage, myomyosis, endometritis, endometrial polyps and other endometrial-related lesions may cause the embryo to fail to implant and affect the success rate of IVF.
5. Age
As the ovaries gradually decline as they age, the quality of the eggs will become worse and worse, and the probability of chromosomal aberrations will increase significantly due to the aging of egg cells, and the success rate of IVF fertility will decrease significantly. At the same time, the age increases, the physical fitness decreases, pregnancy will cause a great burden on the heart, kidneys and liver, and the complications of elderly pregnant women in the process of pregnancy and childbirth increase, and the live birth rate decreases.
Hengjian Overseas Tips: The success rate of IVF depends on many aspects, including endocrine and laboratory conditions, the technical level of the technicians, the age of the patient, the condition of the uterus and ovaries, and whether there are other diseases, among which the woman's age is the most significant. Therefore, it is recommended that you must do a good job of examination in advance before doing IVF, and then carry out targeted maintenance according to the inspection report.
In addition, doing IVF and natural fertility, it is best to do it at the childbearing age stage, so that the success rate will be higher, and finally choose a formal professional hospital, because the medical equipment of large hospitals is more advanced, and there are more clinically experienced doctors.