Isn't that too much? Repeated transplantation failures in test tubes! Baby, it's really not easy to say I love you

Good pregnant parents: Ms. and Mrs. Zeng

Basic information:

The woman is 36 years old, with irregular menstrual cycles for many years, primary infertility, fruitlessness from the outside hospital, 3 failed IVF transplants, and obstructive azoospermia in the man

Let's take a look at Ms. Zeng's test tube journey:

Few eggs are obtained and embryo quality is poor

Three consecutive IVF transplants in the outer courtyard failed

Because she has not been pregnant after marriage, Ms. Zeng has monitored ovulation and room together to prepare for pregnancy, but there is no result.

After artificial insemination, he was still disappointed.

After the failure of human delivery, he switched to IVF fertilization and began to enter the IVF cycle in the outer hospital in May 2019. Because she was 35 years old and immediately broke through the age barrier, the doctor in the outer hospital suggested that she undergo IVF fertility treatment as soon as possible to avoid fertility being dragged down by age.

The first egg retrieval, during the process of ovulation induction, 7 follicles can be seen, but only 4 eggs are obtained in the end, forming 2 cleft embryos, and the quality is very average.

The second egg retrieval, this time more eggs, the last 7 eggs, this time formed 4 embryos, the quality is still average.

The transplant was then initiated:

Primary transplantation, birthing pregnancy;

Secondary transplantation, birthing pregnancy;

Terterilation, birthing pregnancy;

The IVF ended in disappointment and was unable to conceive.

Came to Zhongbi to meet Director Mo Meilan

Adjust the ovulation stimulation regimen to obtain good eggs and good embryos

In the blink of an eye, the time came to the end of 2020, Ms. Zeng packed up her mood and prepared for World War II IVF, and after careful consideration, decided to come to Shenzhen Zhongshan Urology Hospital for IVF.

Ms. Zeng's receiving doctor is Director Mo Meilan, who learned in detail about Ms. Zeng's previous IVF history and found that her previous IVF treatment was a long program, and there were very few eggs obtained, and the quality of the embryos formed was not good.

This treatment led to the development of an antagonist regimen for him. Antagonist regimens can effectively inhibit early-onset LH peaks, prevent premature follicle ovulation, reduce the occurrence of ovarian hyperstimulation syndrome, and improve the safety of IVF in patients with ovarian decline.

Antagonist regimen in the process of promoting ovulation, the need to closely monitor hormonal changes and follicle growth, Director Mo Meilan found that Ms. Zeng's follicles quickly grew very large, and the average woman is very different, he personally adjusted the dosage and egg retrieval time.

In the end, 13 eggs were obtained, 9 were fertilized, and there were 5 blastocysts, which made Ms. Zeng really shocked

Adjust the endometrial environment

Get rid of repeated transplant failures

Because she had had 3 transplants and was not pregnant, Director Mo suggested that Ms. Zeng do hysteroscopy to check whether there were lesions in the uterine cavity environment. The examination found that Ms. Zeng had a condition of uterine cavity adhesions, and Director Mo suggested that Ms. Zeng should be treated first and then transplanted.

In the transplant cycle, because Ms. Zeng has been undergoing hormone replacement therapy after hysteroscopic surgery, Director Mo Meilan has formulated a hormone replacement therapy artificial cycle endometrial preparation plan for Ms. Zeng to improve the pelvic immune environment and increase endometrial tolerance, thereby improving pregnancy outcomes.

After adjusting the endometrial environment, transplant a blastocyst to get pregnant smoothly

#好孕满满

Write in the last words

Ms. Zeng has repeatedly suffered transplant failures,

For this kind of baby mom who has a hard pregnancy,

Two things are critical:

The first point: optimize the ovulation stimulation program + egg retrieval time, increase the number of eggs obtained, and improve the quality of embryos;

The second point: optimize the endometrial preparation protocol, improve the endometrial tolerance, and increase the implantation rate.

Director Mo Meilan

Biography:

Deputy Chief Physician, Assistant Dean, Discipline Leader of Reproductive Fertility Center, Member of clinical Group of Reproductive Medicine Branch of Guangdong Medical Association, Member of Reproductive Medicine Branch of Guangdong Health Management Society. He studied at Sun Yat-sen University and Hong Kong Chinese University. He has been engaged in clinical and research of gynecological endocrinology and human assisted reproduction for more than 20 years.

Practice Areas:

Proficient in the basic theories of gynecological endocrinology, the diagnosis and treatment of infertility and various human assisted reproductive technologies. In particular, personalized ovulation induction treatment programs were formulated for patients with advanced infertility and repeated IVF failures, and they had rich experience in dealing with complications in assisted reproductive technology, and obtained high clinical pregnancy rates and patient satisfaction. The test tube success rate is higher than the domestic average.

Academic Achievements:

A total of 7 projects were undertaken, including 2 provincial-level projects and 5 municipal-level projects. He has published 17 core journal papers at home and abroad, including 3 SCI papers, and won the first prize of the Municipal Science and Technology Progress Award.

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Shenzhen Zhongshan Urology Hospital

In 1986, the First Affiliated Hospital of Sun Yat-sen Medical University sent a medical team headed by Professor Mei Hua to support the development of health in the Shenzhen Special Administrative Region and established the Shenzhen Medical Center of Sun Yat-sen Medical University. In 1997, it was upgraded to Shenzhen Urology Hospital of Sun Yat-sen Medical University. In the same year, Professor Zhuang Guanglun, the "Father of IVF in China", personally founded the first IVF center in Shenzhen in this hospital, which was one of the first reproductive medicine centers approved by the health department to implement assisted reproductive technology, and the first case of IVF babies in Shenzhen was born in our hospital in 1998. In 2003, the hospital was renamed Shenzhen Zhongshan Urology Hospital.

Our hospital focuses on reproductive medicine as the key development direction, and the Reproductive Medicine Center is a standing committee unit of the Reproductive Medicine Branch of the Chinese Medical Association and a vice chairman unit of the Reproductive Medicine Branch of the Guangdong Medical Association. The success rate of IVF in the Reproductive Medicine Center has maintained the advanced level in China, and the diagnosis and treatment rate of recurrent abortion and repeated embryo implantation failure in the Reproductive Immunization Diagnosis and Treatment Center is at the international leading level. Since the establishment of the hospital, around the reproductive medicine year by year to open reproductive fertility center, reproductive immunity diagnosis and treatment department, reproductive fertility Chinese medicine hall, reproductive urology and andrology, gynecology, reproductive medicine clinical research center and other special departments, up to now, our hospital has been difficult to conceive families successfully created more than 30,000 IVF babies.

Hospital mission: to create a healthy life, round your family.

Hospital vision: with reproductive medicine as the main body, to build a modern specialized hospital with cultural value and soul, responsible for patients, employees and the government, and with leading technology.

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