For infertility patients, IVF should be more familiar, but many people are not very familiar with the IVF process, so that before officially entering the IVF cycle, there are doubts and worries everywhere in their hearts, and they cannot calm down to accept IVF fertility, and even affect the success of IVF. So, what does the IVF process look like? What are the steps required to choose IVF fertility?
Hengjian Overseas Introduction: IVF is a common name for in vitro fertilization - embryo transfer technology, which refers to the use of artificial methods to fertilize egg cells and sperm in vitro, and carry out early embryonic development, and then transfer to the mother's uterus to develop and develop the baby.
Ivy before the test tube baby should be prepared:
First of all, we must clarify the cause of infertility and understand whether it is suitable for "IVF". Conditions for DOING IVF: The purpose of IVF embryo transfer technology is to help infertile patients get a healthy, intelligent child, and the principle of eugenics must be followed. Therefore, both men and women who want to do IVF must be physically and mentally healthy, free of genetic diseases, and the age of the woman is generally not more than 40 years old, and the man is not more than 55 years old. Because the woman is too old, the abortion rate after pregnancy after natural conception is high, the possibility of fetal malformations is also greater than that of young people, pregnancy comorbidities increase, and the elderly infertile women who do IVF often react poorly when inducing ovulation, and are forced to abandon treatment in the first stage, the quality of the eggs is relatively poor, the pregnancy rate is low, and it is not easy to succeed. It is best to bring information and certificates of past examinations and treatments to avoid wasting time for repeated examinations.
Information includes:
1. Report of tubal patency examination: X-ray of hysterosalping iodine oil contrast, report of B ultrasound fluid or hospital certificate of laparoscopy or open abdominal surgery.
2. Examination of whether there is ovulation: the pathological report of the endometrium of the daughter within one year and the basal temperature sheet of the recent three months.
3. Husband's semen routine laboratory examination report in the past six months.
4. Hepatitis B surface antigen antibody, e antigen antibody and core antibody, hepatitis C antibody, liver function, blood group test report, woman's erythrocyte sedimentation rate, tuberculin test; Serum HIV antibodies.
Hengjian overseas tips: After the above information is complete, you can go to the infertility treatment center for treatment, before officially entering the cycle, visit the doctor ten days before the expected menstrual period, conduct gynecological examination again, carry out experimental transfer, detect the depth of the uterine cavity and the direction of the catheter when transferring embryos.
What are the steps required to choose IVF fertility?
(1) Stimulation of ovulation: Generally normal women have only one follicle to mature in each natural cycle, but for IVF, this is not enough. In order to obtain multiple eggs, superovulation control methods such as CC/HCG, HMG/HCG, CC/HMG/HCG, GnRH-a/FSH/HCG, etc. are often used to obtain more eggs for use.
(2) Predicting ovulation: To retrieve eggs that mature before ovulation, the ovulation period must first be determined. Clinically, follicle development can be monitored by basal temperature measurement, cervical mucus examination, vaginal smear, and mainly ultrasound to determine the optimal time for hormone induction of ovulation.
(3) Egg collection: when the follicle has not yet ruptured, under laparoscopic transabdominal or B ultrasound surveillance, the mature follicle is punctured by a needle through the vagina, the follicle contents are extracted, and the oocytes are found.
(4) Egg culture: The retrieved oocytes are put into the culture medium for culture so that the eggs are further matured and reach a similar state to the time of ovulation.
(5) In vitro insemination: The husband's semen obtained under sterile conditions is processed so that the sperm has the ability to penetrate the egg, become a small drop of insemination, and then added to the culture medium containing the egg. A new cell, a fertilized egg, is formed by the fusion of the amphoteric prokaryotic nucleus, which is then cultured. When it is divided to 8 to 16 cells, the blastocyst is injected into the uterine floor with a catheter, and it is best to transplant 3 to 4 fertilized eggs at a time, which can improve the success rate of pregnancy after transplantation. The success of blastocyst transplantation depends on the vitality of the fertilized egg itself, whether the endometrium is healthy, and whether there is damage to the transplantation process.
(6) Post-transplant treatment: bedridden for 24 hours after transplantation, restricted activity for 3 to 4 days, on the day of egg retrieval, HCG injection or daily progesterone intramuscular injection after egg retrieval is received daily to reduce early pregnancy miscarriage, and serum HCG level is observed to determine pregnancy 14 or 16 days after transplantation. Successful pregnancies are followed by regular monitoring of fetal development, high-risk pregnancy management, close observation, and fetal preservation measures.