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Another new piece of evidence that low temperatures favor longevity: the hibernation of marmots

Another new piece of evidence that low temperatures favor longevity: the hibernation of marmots

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As a qualified "anti-aging master", how can you not know the ever-changing life extension technology?

Pay attention to the time school to chase the new express column, here contains the freshest life extension information, take you to the first time to link the world's cutting-edge longevity technology trends.

Since Qin Shi Huang began to ask for "elixir of immortality", human beings have been on the road to pursuing longevity for thousands of years. With the rapid development of modern science, the field of anti-aging has made great progress, and related research is changing rapidly, but few scientists pay attention to the mysteries of those long-lived animals.

Until recent years, Professor Steven Austad at the University of Alabama in the United States called on scientists to pay attention to animals that age slower and live longer, rather than just mice in research labs.

The Temporalists have reported on these ideas not long ago, and it is possible to follow us and flip through our historical articles, saying that the evolution of animals over billions of years may have solved the challenges of aging and longevity research that we are currently insurmountable.

Perhaps under the influence of Professor Steven Austad, some scientists began to study animals that aged more slowly, such as the yellow-bellied groundhog, a relative of mice, although they are relatives, but the relationship between the two is not particularly close. The yellow-bellied marmot is a rodent of the family Squirrels, more closely related to squirrels, while mice are of the rodent family. In addition, their life expectancy is also very different, the lifespan of marmots can reach 15-20 years, which is about 10 times the lifespan of mice.

The University of California research team started with yellow-bellied marmots and published their findings in the journal Natural Ecology and Evolution, and they found that yellow-bellied marmots almost stopped aging within 7-8 months of underground hibernation.

Another new piece of evidence that low temperatures favor longevity: the hibernation of marmots

Hibernation is an evolutionary adaptation that allows animals to survive in harsh seasonal environments where there is no food and temperatures are very low, and is common in small mammals such as marmots.

The study is the first study on aging in wild marmots. Researchers have found that yellow-bellied marmots develop this anti-aging phenomenon after sexual maturity (2 years). By analyzing blood samples from yellow-bellied marmots, the researchers found that epigenetic aging in yellow-bellied marmots nearly stopped during hibernation.

Another new piece of evidence that low temperatures favor longevity: the hibernation of marmots

The hibernation of yellow-bellied marmots is actually cyclical, consisting of a period of metabolism suppression that lasts for one or two weeks and a metabolic period that lasts less than a day, and the two cycles alternate. During hibernation, breathing slows down dramatically and body temperature plummets to nearly icy rocks, reducing energy expenditure.

During hibernation, the marmot burns only one gram of fat per day, which is not worth mentioning for the groundhog weighing 5,000 grams to 6,000 grams, and it is not a problem to stick to it for hundreds of days.

In the active summer, the marmots eat and drink heavily and double their weight so they have enough fat to survive the next hibernation period. Groundhogs hibernate for 7-8 months, during which they do not eat or drink, and after hibernation, they eat and drink for about 4 months, which Paipai feels is very similar to the 16:8 fasting method we talked about before (only eating in 8 hours).

All of these conditions associated with hibernation, such as reduced food consumption, low body temperature and reduced metabolism, can be used to fight the aging process and promote longevity, the researchers said. And they think a similar phenomenon will occur in other hibernating mammals because the molecular and physiological changes are similar.

Another new piece of evidence that low temperatures favor longevity: the hibernation of marmots

Since hibernation can delay aging, can the human body also hibernate? With the current technology of human beings, but human beings have learned a lot of things in the pursuit of hibernation, cryotherapy is one of them, can be understood as "low-level" hibernation, schumacher, who woke up after 6 years of coma, relies on cryophotherapy to reduce the impact of long-term coma on the brain. The success of cryotherapy means that human hibernation may be feasible.

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