Does gastroesophageal reflux disease require routine examination of tumor markers? Gastroesophageal reflux disease has a certain relationship with the occurrence of esophageal cancer, and if reflux symptoms persist, the esophagus

Does gastroesophageal reflux disease require routine examination of tumor markers?

Gastroesophageal reflux disease has a certain relationship with the occurrence of esophageal cancer, if reflux symptoms persist, the mucosa of the lower esophagus repeated erosions and ulcers, in the process of mucosal repair may appear Barrett esophagus (BE), and even atypical hyperplasia, which in turn leads to the occurrence of esophageal cancer. Nevertheless, the incidence of esophageal cancer in patients with gastroesophageal reflux disease is not high, and routine examination of tumor markers is usually not required. Detection of tumor markers may only be considered and gastroscopy may also be performed if the following alarm symptoms are present, such as loss of appetite, weight loss, anemia, or the first symptoms or recurrence of symptoms over the age of 50, and if necessary, a biopsy is taken to rule out malignant lesions.

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