Everyone should have heard of uremia, but do you really understand what kind of disease it is?
The so-called uremia is not a lesion that appears in the urinary system, but a chronic renal failure caused by the lack of effective control and continuous development of patients with primary or secondary chronic kidney disease.
And kidney failure is an irreversible process, once the kidney function will become worse and worse, and then lead to a series of symptoms and metabolic disorders in patients, the clinical will be referred to as "chronic kidney failure", chronic kidney failure into the terminal stage, is commonly known as "uremia"!
That is to say, as long as it enters the uremia phase, it means that the patient's kidney function has been completely damaged. It should be known that the main function of the kidneys is to metabolize, generate urine and excrete waste products, so that the balance of water and electrolytes can be maintained and the body is in a normal state.
So the question is, where will the toxins in the body go when the kidney function is lost?
1. Nervous system
When kidney function gradually declines, certain toxic substances accumulate in the body and cause damage to the nervous system, resulting in degeneration of nerve cells. In the early stages of neurological damage, patients may experience insomnia, lack of concentration, and decreased attention.
As the disease progresses, patients may also have peripheral neuropathy, damage to the central nervous system, and manifestations such as apathy, limb numbness, hallucinations and coma, and mental abnormalities;
2. Cardiovascular system
After renal failure, a large number of toxic substances such as uric acid and urea accumulate in the body and are constantly stimulated, which can lead to aseptic pericarditis in patients. In addition, with multiple problems such as acidosis, renal hypertension, and hyperkalemia, patients may also have heart failure, myocardial damage, and arrhythmias.
Relevant studies have shown that cardiovascular disease is one of the main complications of death in uremia patients, especially after entering the terminal stage, cardiovascular disease mortality will progress and increase, accounting for about 45-60% of the causes of death of all uremia patients;
3. Respiratory symptoms
When the stage of severe kidney failure is developed, a large amount of urea accumulates in the body, saliva also contains urea, and bacteria will produce ammonia after decomposing urea, resulting in the presence of urine in the exhaled gas of the patient.
Once a patient with uremia has acidosis, the respiratory rate will become slower, and symptoms such as shortness of breath, shortness of breath, and deep breathing may occur many times. At the same time, patients with uremia can also have uremia pulmonary edema and lung calcification;
4. Gastrointestinal system
There are a large number of bacteria in the intestine, the bacterial urease will decompose urea into ammonia, when the body accumulates too much urea, the amount of ammonia decomposition will increase rapidly, ammonia has the effect of stimulating the gastrointestinal mucosa, can induce uremia patients gastrointestinal mucosa inflammation, superficial small ulcers and other problems, patients often appear loss of appetite, indigestion, nausea and anorexia, vomiting or diarrhea and other symptoms, which is also one of the most common manifestations of uremia.
Written at the end: The kidney is the organ that metabolizes and expels toxins throughout the body, and it is also an important endocrine organ. Therefore, once the kidneys have problems and cannot metabolize toxins, the effects will be systemic, and patients will even die due to various complications. Therefore, do not ignore chronic kidney disease, once it appears, you need to actively cooperate with the doctor for treatment.