Gout is an arthritis disease, once the disease, the patient's joints will appear red, swollen, hot and painful reaction, at this time need to take the corresponding drugs quickly for treatment, which can not only alleviate discomfort, but also inhibit the excessive production of uric acid in the body, and improve the excretion function of uric acid.
However, after these drugs enter the human body, many need to be metabolized in the kidneys, and the kidney metabolic function of gout patients has been abnormal, so many people want to know whether eating too many gout drugs has an impact on the kidneys.
Does eating too much gout medicine have an effect on the kidneys?
The so-called "three points of poisoning", once all drugs excessively enter the human body, in addition to causing certain damage to the liver, it will also affect kidney health.
The drug for the treatment of gout also needs to be metabolized in the kidneys, which is necessary for patients with abnormal kidney metabolic function, and the damage of the drug to the kidneys is bound to appear, and it will be more obvious.
For example, the most commonly used colchicine, this type of drug once taken in large quantities, it is easy to cause kidney deficiency. In addition, after taking some acid-lowering drugs, it will promote the excretion of some uric acid by the kidneys, which is bound to increase the burden on the kidneys.
Therefore, for gout patients, when taking medicine, it must be strictly followed by the doctor's instructions. In addition, before taking the drug, it is best to choose the right drug according to your own kidney function indicators.
What indicators can kidney function be measured again?
1. Blood creatinine
Serum creatinine in healthy adult populations remained at 53 to 106 micromoles per liter for men and 44 to 97 micromoles per liter for women. If the serum creatinine value is higher than normal and persistently above normal, then the kidney function has been abnormal.
2. Endogenous creatinine clearance
Creatinine clearance in healthy men is generally 105 plus or minus 20 ml per cent, while the normal value for women is 95 plus minus 20 ml per cent. If endogenous creatinine clearance is less than 80% of normal, it is a manifestation of decreased renal function.
3. Blood uric acid
The normal blood uric acid value is 237.9 to 356.9 micromoles per liter for men, and the normal blood uric acid value is 178.4 to 297.4 micromoles per liter for healthy women. The higher the value of blood uric acid, the more impaired the filtration rate function of the glomeruli. 4. Serum urea nitrogen
The urea nitrogen value of healthy adults is 2.86 to 7.14 millimoles per liter, but because serum urea nitrogen is a catabolite of amino acids in the human body, this measured value generally changes according to the human diet.
5. Glomerular filtration rate
By examining the glomerular filtration rate, an indicator of the function of the earliest glomerular filtration rate can be obtained. Generally clinically, this indicator is reflected by creatinine clearance.
6. Urine volume
For normal people, the daily urine output is maintained at about 800 to 1500 ml. For people who often take gout drugs, in the case of no reduction in water intake, the amount of urine suddenly decreases or anuria occurs, which is generally caused by kidney failure.
All in all, for patients with gout, due to the redness, swelling, heat and pain inflammation response, and the uric acid value in the body will be relatively high, it is necessary to take some painkillers, anti-inflammatories and uric acid-lowering drugs. However, due to the abnormality of the patient's kidney function, once these drugs are taken for a long time, it is bound to have a relatively large impact on the kidneys.
Therefore, gout patients must strictly follow the doctor's instructions to take drugs, and can also detect their kidney function according to the above 6 indicators. Then through these indicators, under the guidance of the doctor, choose the right drug for yourself, in order to minimize the damage of the drug to the kidneys.