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Central nervous system (CNS) tumors are the most common solid tumors in children, ranking second in pediatric malignancies (accounting for 20%-25% of pediatric malignancies), and are one of the causes of malignant neoplasms death in children.
At present, with the continuous improvement of imaging diagnostic techniques, the incidence of children's central nervous system tumors is increasing year by year, but its causative factors are not yet clear [1].
Given that many drugs have the potential to have teratogenic effects on the fetus, if a pregnant woman uses hormonal contraceptives during pregnancy, will it lead to an increased risk of CNS tumors in her children after birth?

Source: Screenshot of literature
Recently, Marie Hargreave et al. published a paper in the Journal of the American Medical Association (JAMA) demonstrating a correlation between hormonal contraception used by mothers and their children's risk of CNS tumors in the Danish pediatric population [2]. Let's take a look at today's newsletter!