I don't know if you have been watching the TV series "Dear Child" recently?
This TV series mainly tells the story of a divorced parent who went through to save their daughter with leukemia.
However, after watching this TV series, many people have found that --- why are today's domestic dramas more and more disturbing?
After childbirth, pregnant mothers want water to be ignored by mothers-in-law, children's mothers are about to give birth to the father of the child, and the three major children's first birthday feast kicks and explodes the husband's derailment, and a series of plots really make many viewers watch the blood pressure soar.
However, when the daughter was diagnosed with leukemia, this acute lymphoblastic leukemia and the new dilemma of urgent need for bone marrow transplantation.
It was hard to wait for the bone marrow to be given back, but the result suddenly changed, and the doctor proposed a "last resort" ---- have another child from the biological parents.
Although the plot of "giving birth to a baby and saving a baby" is artistically appealing, from a professional medical point of view, this kind of plot is particularly wrong and "outrageous".
Acute lymphoblastic leukemia, what exactly is the disease?
The so-called leukemia is actually a malignant tumor disease in the hematopoietic system, which is related to genetic, physical, chemical, abnormal immune function, viral infection, bad living habits and other reasons.
According to the progression of the disease, it can be divided into acute and chronic, and once the disease is suffered, the patient's body will have a variety of abnormal symptoms.
1. Fever
Once the disease is developed, the patient will have obvious febrile symptoms.
This fever is mainly caused by infection, which can be low-grade or high-heat, and high fever can generally reach 39 to 40 degrees or more.
High fever often suggests a secondary infection that can occur in various parts of the body, such as the lungs, gums, perianal area, etc., and in severe cases sepsis and sepsis may occur.
2. Bleeding
People with this disease have obvious bleeding throughout the body, of which bleeding gums, nosebleeds and ecchymosis of the skin are the most common, and bleeding intracranial and urinary systems is relatively rare.
This bleeding is mainly caused by problems with the circulatory system. In severe cases, it may also cause heavy bleeding in the digestive tract or respiratory tract.
3. Anemia
In the early stages, because of bleeding in various parts of the body, patients may develop anemia, and then show symptoms such as pallor and fatigue.
Most patients already have moderate to severe anemia at the time of presentation, and some acute patients have a shorter course of illness and may not have major bleeding.
4. Joint pain
The disease will cause joint pain due to infiltration, which is more intense, the site is not fixed, mainly occurs in the limbs, spine, pelvis, sternum, etc., and will limit daily activities.
Do acute lymphocytes need a bone marrow transplant? Eight children have been cured with chemotherapy alone
In fact, tv drama plots like "Dear Little Kids" often make many viewers have the concept that "childhood leukemia is difficult to treat".
But in fact, as the most common type of leukemia in children, acute lymphoblastic leukemia accounts for 80% of children. 80% of people with acute lymphoblastic leukemia do not actually need a bone marrow transplant at all, and can be cured by chemotherapy.
Yes, I was right, and you heard it right.
Pediatric acute lymphoblastic leukemia does not actually talk much about survival rates for several years, but directly says cure, because its prognosis is better, usually 5 years do not recur, basically 99% probability will not recur.
Even with a bone marrow transplant, the best donors did not come from their fellow citizens
In fact, bone marrow transplantation is only considered if the condition is particularly high-risk, or if severe drug resistance develops after chemotherapy, or if leukemia recurs.
But these conditions themselves are not high, about 10%-15%, even if transplantation is to be done, the medical community will not prefer HLA (that is, human leukocyte antigen, half inherited from the father, half inherited from the mother) matching fully compatible siblings as donors.
This also means that plots like the "baby save the baby" in the TV series are actually not advocated.
This is because lymphocytic leukemia is not the same as myeloid leukemia, it belongs to the cancerous transformation of lymphocytes, which will recognize the remaining cancer cells in the patient's body after transplantation, which can easily lead to cancer recurrence.
Nowadays, with the continuous improvement of medical standards, there is actually no need to have too much fear or anxiety about children's acute lymphocytes.
We need to do a good job of ----- believe in science, believe in medicine.