The number of people who drink alcohol and the consumption of alcohol in the mainland are increasing year by year, and the consequent consequence is that digestive system diseases caused by drinking alcohol have become a serious social and medical problem.
Digestive system diseases caused by alcohol consumption are mostly gastritis, gastric ulcer, duodenal ulcer, alcoholic liver disease, cirrhosis, etc.; long-term alcohol consumption can also induce intestinal metaplasia, and intestinal metaplasia is a stage of excessive gastric mucosal lesions to gastric cancer.
In the hospital emergency department, it is often possible to encounter drunk, or even alcohol "poisoning", in addition to the presence of different degrees of consciousness disorders when admitted to the hospital, patients will also have more serious gastrointestinal mucosal damage.
As a strong damage factor, ethanol can not only directly damage the gastric mucosa, but also seriously affect the metabolism of the gastric mucosa, resulting in microcirculation disorders of the mucosa, increasing the permeability of the mucosal blood vessels, stasis of mucosal blood flow, resulting in hyperemia of the mucous membrane, edema, and even necrosis of mucosal epithelial cells. If the patient has Helicobacter pylori infection, it can worsen the damage of ethanol to the gastric mucosa.
Heavy alcohol consumption is detrimental to health
In hospital emergencies, the opioid receptor antagonist naloxone is used primarily to relieve acute ethanolosis. However, in the process of use of naloxone, there are increased blood pressure, rapid heart rate, vomiting, diarrhea, abdominal pain, and even serious adverse reactions such as arrhythmias and pulmonary edema, which makes the clinical use subject to some restrictions.
Naloxone instructions
At present, there are many clinical studies, among which the herbs that have studied the effect of alcohol are kudzu root, astragalus and so on.
Kudzu root, sweet taste, flat, slightly cool, into the spleen, stomach meridians, has the effect of relieving muscle fever, quenching thirst, raising the sun and stopping diarrhea. Experimental studies have found that kudzu root can improve the activity of antioxidant enzymes, reduce the production of lipid peroxides, and play a role in detoxifying and protecting liver cells.
Astragalus is one of the representatives of traditional Chinese medicine to strengthen the spleen and qi, and has the medium effects of tonifying qi and fixing the table, diuretic toxin, sores and muscle, and qi supplementation. At present, there are dozens of chemical components isolated from astragalus, mainly including saponins, flavonoids, polysaccharide components, pharmacological studies have found that astragalus can regulate the body's immunity, protect cardiovascular and cerebrovascular diseases, hypoglycemia and other effects.
radix astragali
The Qing Dynasty physician's "Zhengzhi Hui Supplement", the book records that the astragalus kudzu soup, the formula is mainly composed of astragalus, kudzu root, the main treatment of drunkenness, internal heat and external cold, for the strength of the expression of the agent.
The active ingredient in kudzu root is isoflavones, of which puerarin is the main component, which has the effect of dilating blood vessels, reducing vascular resistance, fighting vasospasm, inhibiting platelet aggregation, reducing blood viscosity, and improving microcirculation.
Chinese herbal medicine - kudzu root
The mechanisms by which puerarin is used for the effect of alcoholism include the following:
1. Reduce blood viscosity, improve blood rheological indicators, improve microcirculation, help accelerate blood flow, prevent red blood cell aggregation, help prevent and eliminate microthrombosis.
2. Dilate blood vessels, reduce vascular resistance, increase cerebral blood flow, improve microcirculation and thus promote the functional recovery of damaged brain cells;
Kudzu is based on pharmacological metabolic pathways
3. Inhibit reducing coenzyme │ (NADH), improve hepatocyte metabolism, reduce the accumulation of various toxic substances in the body, and thus play a role in promoting awakening.
Long heart: Whether you use naloxone, or use traditional Chinese medicine to relieve alcohol, say a thousand, say ten thousand, or hope that you drink less, the Spring Festival is coming, I hope you and your family have a reunion year, a healthy year, I wish you health, peace and happiness!
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bibliography:
1. Zhang Zhaozhi, et al. Efficacy of kudzu in the treatment of severe acute alcoholism in 60 cases[J].Chinese Journal of Integrative Traditional and Western Medicine,2005,9(12):270.
2. Lai Huili. Protection of astragalus-kudzu on ethanol-induced gastric mucosal damage[J].Dissertation of Guangzhou University of Traditional Chinese Medicine.2015,5.
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