Duck tambusu virus (DTMUV)
In 2014, researchers at the Shanghai Veterinary Research Institute of the Chinese Academy of Agricultural Sciences isolated and identified the pathogen of the infectious disease from the sick duck, and named it "Duck Tambusu Virus" (DTMUV), also known as duck egg laying down syndrome, duck infectious ovaryitis, duck yellow virus and so on. Ducks infected with this virus seem to have anorexia and do not like to eat; egg production has dropped rapidly, from more than 90% to less than 10%, and in severe cases, it will even stop production; the fertilization rate of eggs laid by sick ducks will be reduced by 10%; it will also cause high fever and slow growth of ducks, causing huge economic losses to the waterfowl industry.
Atlas of Tambusu virus
Researchers have found that it not only causes duck disease, but also can be isolated from chickens, pigeons and other land birds, indicating that the duck Tambusu virus disease host is widespread.
Promoting the development of vaccines and diagnostic reagents for duck tambusu virus disease is an urgent issue to be solved. Only by establishing an accurate and scientific epidemic prevention barrier can we support the "protective umbrella" for the high-quality development of the poultry industry.
The gospel of the poultry world is coming, and the duck tambusu virus disease inactivated vaccine and diagnostic reagents are on the market!
Jointly developed by the Institute of Animal Husbandry and Veterinary Medicine of Beijing Academy of Agriculture and Forestry Sciences, Ruipu (Baoding) Biopharmaceutical Co., Ltd., China Veterinary Drug Supervision Institute and Gansu Jianshun Biotechnology Co., Ltd., through the systematic study of key technologies of virus biology, vaccines and diagnostic reagents, supporting prevention and control technologies were created, and the inactivated vaccine (HB strain) of duck tambusu virus disease and the antigen of duck tambusu virus hemagglutination test were successively introduced, which brought hope to the poultry industry that was "no vaccine preventable" and "no reagent to diagnose" in the past.
Duck Tambusu virus disease inactivated vaccine (HB strain)
Duck tambusu virus disease hemagglutination inhibitory test antigen (HB strain)
Duck tambusu virus disease positive serum versus negative serum
Duck Tambusu virus disease inactivated vaccine (HB strain)
- The world's first inactivated tambusu virus vaccine
Duck tambusu virus disease inactivated vaccine (HB strain) seed poison is an HB strain with excellent immunogenicity, and the results of the attack and protection experiment show that the meat duck is immune, which effectively reduces the detoxification and detoxification rate of the duck population and improves the survival rate; the breeding duck immunity protects the duck population from infection and protects the egg laying performance.
Duck tambusu virus hemagnetic suppression test antigen, positive serum, and negative serum
Antigens should be positive for duck tambusu virus positive serum, duck tambusu virus negative serum, duck plague virus positive serum, duck hepatitis A virus type 1 positive serum, duck hepatitis A virus type 3 positive serum, Newcastle disease virus positive serum, egg reduction syndrome virus positive serum, avian influenza virus H5 subtype, H7 subtype and H9 subtype positive serum should be negative. For the detection of DUCK TAMBUSU virus HI antibody, diluted with a special antigen dilution.
The potency of positive serum HI antibodies should be no less than 1:80, and the potency of negative serum HI antibodies should be less than 1:10. In addition to the positive serum response to the Duck Tambusu virus HI test antigen, the Newcastle disease virus HI test antigen, the egg reduction syndrome virus HI test antigen, and the avian influenza virus H5 subtype, H7 subtype and H9 subtype HI test antigen should be negative. Reference serum for positive and negative tests for duck tambusu virus HI antibody.
Duck tambusu virus hemocoagulation inhibition test
The Ministry of Agriculture and Rural Affairs recently issued the "14th Five-Year Plan" National Agricultural and Rural Science and Technology Development Plan, aiming to break through a number of "card neck" technologies and short-board technologies that are subject to people by 2025, and the original innovation ability in the agricultural field has been greatly improved, including animal vaccines, biological breeding and other fields in the world's leading level.
Vaccines and diagnostic reagents are products that are just needed for animal disease prevention and control. The hemagglutination suppression test (HI) is one of the diagnostic methods recommended by the World Organisation for Animal Health (OIE). The advent of inactivated vaccines and diagnostic reagents for duck tambusu virus disease will surely effectively fill the gap in China's poultry vaccine market.
Editor: Zhang Xueting| Editor-in-Chief: Shang Qinru | Supervisor: Ren Min