When it comes to statin lipid-lowering drugs, the most commonly used sentence is: "Eat statins, hurt the liver and kidneys!" So, is this statement true? Is it alarmist, or does everyone need attention? In particular, will statin lipid-lowering drugs cause kidney damage? This is indeed a big problem. Today, Dr. Zhang Zhiying explained this problem to everyone clearly.
Does statin hurt the kidneys?
So, is this statement true? This is indeed something that we need to explain to you carefully. In fact, when it comes to liver injury, this is indeed a possible adverse reaction. This is also the reason why many people take statin lipid-lowering drugs and need to check liver function regularly. However, rationally speaking, for many patients with cardiovascular and cerebrovascular diseases and hyperlipidemia, the benefits of statins are definitely greater than the liver damage that may be brought, and these liver damages are basically reversible. So, there is no need to worry and worry excessively.
Our focus today is to tell you about "eating statin lipid-lowering drugs, does it hurt the kidneys?" "This topic. Speaking of which, some studies and meta-analyses at home and abroad have shown that statin lipid-lowering drugs can reduce the risk of cardiovascular disease in kidney disease, especially the incidence of cardiovascular and cerebrovascular diseases in patients with mild renal insufficiency, and no damage to the kidneys has been seen. At the same time, the world's well-known JUPITER study also shows that statin can reduce the risk of cardiovascular and cerebrovascular diseases in patients with chronic kidney disease, which is no different from placebo for the safety of the kidneys, and is safe. Some large meta-analyses have shown that rosuvastatin and atorvastatin do not increase the incidence of proteinuria in patients, and even with mild proteinuria, it cannot be considered kidney damage. In fact, even the president of the United States is taking statin lipid-lowering drugs to control low-density lipoproteins, such as former U.S. President Bill Clinton and several other U.S. presidents, who have been taking statin lipid-lowering drugs for many years to control blood lipids.
Several U.S. presidents are also using statin lipid-lowering drugs
Therefore, at this stage, the guidelines of several large medical associations around the world, such as the European Blood Lipid Guidelines and the American Cholesterol Treatment Guidelines, do not mention the kidney damage of the Tatin as a routine adverse reaction. This point also hopes that everyone can know that it hurts the kidneys without mentioning statin, which is also unfair to statin lipid-lowering drugs.
In fact, speaking of this, everyone may have seen clearly that statin lipid-lowering drugs have no obvious adverse reactions to the patient's kidneys, or the side effects that the people say, saying that he is injuring the kidneys, this statement is unreliable and untenable. For a small number of friends who have proteinuria after oral statin, this is indeed a condition, especially in patients with oral rosuvastatin. However, this change is more likely to show transient changes, not permanent damage, and some people can even slowly return to normal. Of course, if you find this change, you can also adjust the treatment plan of lipid-lowering drugs under the guidance of a professional doctor, or seek medical treatment to find out whether there are other causes, which everyone should also pay attention to.