Statin lipid-lowering drugs, such as simvastatin, atorvastatin, rosuvastatin, pitvastatin, pravastatin, fluvastatin, lipid profile, etc., have properly become the most famous "drug stars" nowadays. The reason behind this is nothing more than two points, the first is because there are more patients with hyperlipidemia, and blood lipids are reduced by eating statin lipid-lowering drugs; the second is because there are more patients with cardiovascular and cerebrovascular diseases, and blood lipids are reduced by eating statin lipid-lowering drugs, thereby controlling the occurrence and development of cardiovascular and cerebrovascular diseases. Because of these two reasons, more and more people are eating statin now.
However, in the process of eating statin, what problems do we need to pay attention to? Speaking of which, I would like to explain to you a common statin side effect, that is, muscle damage, and severe muscle damage even hurts the kidneys. Therefore, everyone who eats statin friends, must read this article.
Eat statin lipid-lowering drugs, daily regular examination, it is necessary to routinely check an indicator called creatine kinase, if this indicator is high, it is necessary to carry out corresponding treatment.
1. Assessed by creatine kinase
Speaking of creatine kinase, this indicator actually reflects the damage to muscles caused by statin lipid-lowering drugs. Some people will have muscle pain after taking statins, especially the discomfort symptoms of large muscle groups such as thighs and buttocks, so it is necessary to pay attention to checking creatine kinase. If the test results are elevated, it should also be noted that there are 3 cases to differentiate:
Creatine kinase is elevated, but the value is less than 4 times the upper limit of normal, at this time depending on the patient's symptoms, if the symptoms are obvious, you can consider adjusting the statin regimen. If the symptoms are not obvious, further observation can be made.
Creatine kinase is elevated, the specific value is greater than the upper limit of normal 4 times, but less than 10 times, at this time can consider adjusting the use of statin lipid-lowering drugs under the guidance of a doctor.
Creatine kinase is elevated, the specific value is greater than 10 times the upper limit of normal, at this time can not exclude the presence of rhabdomyolysis, it is recommended that the professional doctor immediately stop the statin, while hospitalization for further treatment. Because in this case, severe rhabdomyolysis, a substantial increase in creatine kinase, and kidney damage may also be caused, requiring hospitalization is more secure. #人人关注肾健康 #
Elevated creatine kinase
2. Pass the symptom assessment
In real life, how to initially identify the muscle pain you have without testing is caused by eating statin lipid-lowering drugs? Dr. Zhang Zhiying summed up his own small experience for everyone: If you eat statin lipid-lowering drugs, there is muscle fatigue and soreness, note that this change occurs after eating statin, rather than before eating statin, at this time this discomfort can not be excluded from eating statin has something to do with eating statin.
At the same time, if your discomfort does not come from small joints, but mainly from large muscle groups, such as thighs, buttocks, calves, stomach, upper arms and other large muscle groups, then this is more likely to be it. And if your discomfort is persistently uncomfortable, rather than intermittent seizures passing for a while, this is more likely. And if at the same time your discomfort is bilaterally symmetrical, rather than unilaterally asymmetrical, this cannot be excluded.
It can be summed up simply into one sentence: the uncomfortable symptoms of large muscle groups, such as fatigue and soreness, if they occur after eating statin, showing continuous and bilateral symmetry, it is likely to be because of the muscle damage caused by eating statin. At this time, everyone is likely to find a professional doctor to check and adjust the drug.
Symptoms of discomfort in large muscle groups are obvious
I hope that Dr. Zhang Zhiying's introduction to you today can help everyone, especially those friends who are taking statin lipid-lowering drugs. At the same time, I hope that everyone can correctly understand the benefits and risks of statin lipid-lowering drugs, although there are various statements about statin side effects on the Internet, but for many people, the benefits of eating statin are far greater than the risks, many people should eat or eat, the key is to use statin under the guidance of a doctor, and regularly review it. And I have to say that most of these side effects brought by statin are reversible, and they will disappear after stopping the drug, so everyone does not have to mention "statin" to worry about side effects, which is unfounded.