Mama Chen, what do the CC, CT, and TT types in the folic acid metabolic capacity examination report refer to?
Testing of folic acid metabolic capacity can prevent fetal neural tube defects early, reduce spontaneous abortion in pregnant women, preterm birth, intrauterine growth retardation of fetuses, and hypertension in pregnancy.
Folic acid supplementation during pregnancy has become common knowledge and is accepted by the majority of women. Because folic acid is the basic substance of the fetal synthetic neural tube, if folic acid is lacking, it is easy to cause anencephaly, spina bifida, meningocecal bulge and so on. Therefore, in the first trimester, a large amount of folic acid is needed to promote the development of neural tubes and prevent the occurrence of fetal neural tube defects.
Folate deficiency can also easily cause anemia, as folic acid is a building block for the synthesis of hemoglobin. Folic acid also has the effect of preventing hypertension in pregnancy and diabetes mellitus during pregnancy, reducing the risk of preeclampsia during pregnancy. Therefore, proper oral administration of folic acid during pregnancy can prevent the occurrence of pregnancy complications.
Detecting the metabolism of folic acid can help diagnose, treat and prevent diseases that occur due to disorders of folate metabolism. The CC type, CT type, and TT type in the report sheet you said need to be tested by blood testing for folic acid metabolism ability genetic testing, that is, to check whether the absorption and excretion function of folic acid is normal. Folic acid metabolism gene testing is the detection of MTHFR gene, MTRR gene and its related sites, which can directly detect whether there is a genetic defect in folic acid metabolism (that is, the ability to use folic acid), so as to recommend a more accurate amount of folic acid supplement according to the risk of the test results.
Women who are trying to conceive and women in the first trimester generally need to have a genetic test for folate metabolism. The test results can be divided into three types:
They are CC type, CT type, and TT type, which represent three different metabolic conditions of folic acid.
CC type, indicating that the enzyme activity required in the process of folic acid metabolism in the body is very good, is normal, and there is no disorder of folate metabolism.
CT type, indicating a decrease in folic acid metabolism enzyme activity in the body, but can also maintain basic folate metabolism.
Type TT, then severe disorders of folate metabolism.
Tests for folate metabolism are critical to guiding pregnant women in preparing for pregnancy and to supplementing with folic acid throughout pregnancy. If the result is CC type, it is recommended that folic acid supplementation of 400 mg per day is recommended for the first trimester of pregnancy and the first trimester of pregnancy. In the case of CT type, it is recommended to take 400 mg of folic acid per day from the first trimester of pregnancy to the entire pregnancy. The TT type recommends taking 800 mg of folic acid per day until the baby is born.