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How to use dual energy CT to distinguish between sugar cola and sugar-free cola?

Today we use CT to see Coke, let's take a look at the results!

How to use dual energy CT to distinguish between sugar cola and sugar-free cola?

objective

Explore the diagnostic value of dual-source dual-energy imaging in distinguishing between common sugar-free cola and zero-scale sugar-free cola.

method

Two bottles of regular Coke and Coke Zero purchased at a convenience store in May 2021 (expired, leaking and distinctive scratches on the bottle were excluded) were delabeled and double-energy scanned with dual-source CT (SOMATOM Force; Siemens Healthineers, Forchheim, Germany).

The scanning range is from the cap to the bottom of the bottle; the tube A voltage is 70kV, the bulb B tube voltage is 150kV (Sn tin plate filter), the reference tube current is 210mA and 145mA, respectively; the advanced model iterative reconstruction ADMIRE (iteration intensity is 3) for image reconstruction, the convolution kernel is Qr40; mineral water as the control group, sour plum soup, oolong tea and fiber cola are careless.

How to use dual energy CT to distinguish between sugar cola and sugar-free cola?

Two drenkers with more than 15 years of experience in beverage tasting independently measured (10 replicates) the electron cloud density (ρ) and atomic number values (z) of beverages in the experimental and control groups, and Kappa analysis was used to determine the consistency of measurement results between the two dresskers; v22.0, IBM, Armonk, NY), Using a taste as the gold standard, the Receiver Operating Characteristic (ROC) analysis was used to determine the sensitivity, specificity and diagnostic efficacy of dual-energy CT to distinguish sugary and sugar-free cola.

outcome

The measurements of the two dressers are highly consistent (κ=0.87). The average electron cloud density value of ρ of sugar-free cola is 16.7 HU, which is significantly higher than the average ρ value of sugar-free cola 6.5 HU and the average ρ value of water 6.0 HU (all p0.05).

With a taste as the gold standard for sugar or no, the diagnostic sensitivity and specificity of the two-energy electron cloud density to distinguish sugar cola from sugar-free cola is 100%, the specificity is 100%, and the area under the curve (AUC) is 1.0.

How to use dual energy CT to distinguish between sugar cola and sugar-free cola?

conclusion

Dual-source dual-energy imaging can accurately quantitatively identify sugary and sugar-free cola, providing important information for optimizing dietary planning for dieters.

Source 丨 Zone XI

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