There have been three generations of IVF technology since its birth, of which the third generation of IVF technology is currently the most advanced, but many people do not understand more than the third generation of IVF technology, so what is the third generation of IVF surgery like? How is it operated, and what are the specific processes?
Hengjian Overseas said that in fact, the test tube process is much the same, all of which have experienced the cultivation and screening of artificial insemination embryos, embryo transfer and pregnancy testing.
The third generation of IVF technology is the preimplantation of embryos genetic diagnosis technology by screening embryos with normal genes for conception, so as to prevent the birth of the next generation of genetically abnormal children, to prevent the occurrence of rare diseases, which is commonly known as "third generation IVF". Although the incidence of rare diseases is low, once a newborn has these diseases, the minor can affect the child's life, bringing great pain and financial burden to the family, and the severe can be disabled or die. Therefore, the eugenic and eugenic function of the third generation of IVF is still very important.
1. Ovulation induction therapy
Since not every egg can be fertilized, not every fertilized egg can develop into a viable embryo, so multiple eggs must be obtained from the woman's body to ensure that there are embryos that can be transferred, which requires ovulation induction treatment for women.
2. Egg retrieval
Under the guidance of ultrasound B, the doctor applies a special egg retrieval needle to puncture the mature follicles through the vagina and aspirate the eggs. Egg retrieval is usually performed under intravenous anesthesia, so women do not feel the pain caused by the puncture process.
3.IVF
Sperm retrieval: When a woman retrieves an egg, a male performs a sperm retrieval. After the semen undergoes a special washing process, the sperm eggs are placed in a special medium in order to combine naturally. This is called conventional fertilization.
4. Screening diagnosis
This is a unique technology of the third generation of IVF, through genetic screening can exclude bad genes, ensure the quality of embryos healthy, thereby improving the success rate of IVF and avoiding the birth of unhealthy babies.
5. Embryo transfer
A few days after fertilization, a very thin embryo transfer tube is applied, the best embryo is transferred into the mother's uterus through the cervix, and the number of embryos transferred is determined according to age, embryo quality and previous IVF outcomes, usually 2 to 3 embryos. In recent years, in order to reduce the rate of multiple pregnancies, some centers have opted for single embryo transfer, or up to 2 embryos.
Because the embryo transfer tube is very thin and the yisheng movements are gentle, the patient usually does not have any pain.
6. Luteal support
Due to the application of GnRH agonists/antagonists and ovulation-stimulating Y, as well as the loss of follicular granule cells due to egg retrieval, women usually have lutein insufficiency during the egg retrieval cycle and require luteal supplementation/support with progesterone and/or chorionic gonadotropin. If you are not pregnant, stop progesterone and wait for menstruation. If pregnant, progesterone is continued, usually 3 weeks after ultrasound sees fetal heartbeat.
7. Determination of pregnancy
Serum hCG is measured 14 days after embryo transfer to determine pregnancy. Serum HCG is measured again 21 days after embryo transfer to understand how the embryo is developing. 30 days after embryo transfer, an ultrasound examination of the yin tract determines whether there is an intrauterine pregnancy and whether there is fetal heartbeat.