Regarding IVF embryo transfer, I believe many sisters are very entangled, transfer one or two? If both are in bed, they are twins! It seems better to have two children at once! As the saying goes, "greedy chews more than rotten", in fact, IVF transfer one embryo is better than transferring two embryos!
In 2017, the American Annual Conference on Reproductive Medicine (ARSM) Embryo Transfer Guidelines recommended:
patient
Patients aged 35 to 37 years are encouraged to perform single embryo transfers;
Patients aged 38 to 40 years old can be transferred to a single embryo or the number of embryos transferred shall not exceed 3 embryos at the cleft stage or 2 blastocysts;
Patients aged 41 to 42 years old can be transferred per embryo or the number of embryos transferred must not exceed 4 cleft embryos or 3 blastocysts.
In 2003, the Ministry of Health issued the "Code of Human Assisted Reproductive Technology", which stated that the number of embryos transferred per cycle should not exceed 3, of which the first transfer cycle under 35 years old should not exceed 2.
In 2016, the first laboratory group of the Reproductive Branch of the Chinese Medical Association issued the "Expert Consensus on Human In Vitro Fertilization - Embryo Transfer Laboratory Operation", which proposed that single embryo transfer is recommended for high-risk patients with scard uterus, double uterus and other malformed uterus, loose internal cervical opening, and too short height.
Why do fertility experts recommend singleton transplants?
Twin and multiple pregnancies have a higher incidence of preterm birth and a higher incidence of complications associated with preterm birth than single-child pregnancies. Studies report an 8% incidence of preterm birth in singleton pregnancies and 42% at gestational age less than 37 weeks for twin pregnancies. And the cost of post-diagnosis and treatment of premature babies is too heavy for families, and the cost of treatment is about 10 times that of full-term babies. In addition, the incidence of gestational hypertension, gestational diabetes mellitus, placental abruption, caesarean section rate, postpartum hemorrhage rate, and postpartum depression increased in multiple pregnant mothers.
Opting for a single embryo transfer is an effective measure that prevents multiple pregnancies and does not reduce the rate of live births. A 2014 Cochrane database showed that the live birth rate (LBR) after a cycle of two embryo transfers was 45%, and the live birth rate of one cycle selective single embryo transfer was slightly lower at 24% to 33%. However, the live birth rate after two consecutive single embryo transfers ranged from 31% to 44%. And two consecutive single birth rate transplants can reduce the proportion of low-birth-weight infants and caesarean sections, reduce the incidence of preterm birth, reduce the length of hospital stay in neonatal intensive care, the mother's pregnancy period, postpartum medical care and nursing, and improve pregnancy outcomes. Clinical pregnancy rates of single and double embryo transfer were selected (44.6% vs. 44.7%), live birth rates (34.9% vs.34.2%), and lower double embryo rates (9.2% vs. 2.4%), respectively.
To sum up, ivory infant transfer of one embryo is better than the transfer of two embryos! The pregnancy rates of IVF singleton and twin transplants do not differ much. It is recommended that IVF families do not cling too much to twins and multiple births; the health of the baby and pregnant mother is the most important.