Source: The First Courtyard of Zhejiang University
Today's parents are more concerned about whether their children are precocious, and through our daily science, they also know how to avoid it.
But 4-year-old Duoduo (pseudonym) developed her chest prematurely despite being under her mother's scientific care
Duoduo's mother was puzzled until she did this test
Only to know that Duoduo's precocious puberty is because of her father...
Duo Duo is 4 years old this year, people love it, because Duo Duo's parents are not tall, Duo Duo's father is 165cm, Duo Duo's mother is 158 cm, so Duo Duo's mother pays special attention to the growth and development of children, and the diet of Duo Duo has always been very scientific.
Not long ago, when Duoduo's mother bathed Duoduo, she found that Duoduo's chest became larger, and there was a hard block when she touched it, so she immediately took Duoduo to the headquarters of the First Affiliated Hospital of Zhejiang University School of Medicine for a pediatric examination.
After a series of examinations, double breast B2 stage, pubic hair PH1 stage, indicating development, indicating that the flowers are precocious. Chief physician Wang Chunlin, director of the Department of Pediatrics, carefully consulted and found that Duoduo had a reasonable diet, and her height and weight were at the normal level of her peers, and it was unusual for precocious puberty to occur in general.
"Did your child have any previous medical history?" Duoduo's mother opened the conversation box for this reason, saying that Duoduo was born as an unconscious child, with congenital heart disease and esophageal atresia surgery.
"I suggest that your family do a genetic test for genetic diseases." Test reports suggest that The symptoms of precocious puberty may have come from a mutation in the MKRN3 gene, which was inherited from the father, and since the father was an adult, it is impossible to prove whether the father had premature puberty at an early age.
Because the precocious puberty of the flowers is because of the inheritance of mutated genes, it is still relatively early to discover, as long as observation and follow-up can be done, but the possibility of subsequent injections to inhibit development is very large. "What is more troublesome is that this mutated gene of Duoduo's father is very likely to continue to be passed on to the next generation, and once the second child or daughter inherits this gene, there will be symptoms of precocious puberty."
Director Wang Chunlin said that children are the main population of genetic diseases, in the diagnosis of some diseases, children's genetic disease genetic testing can be a good guide for pediatricians in clinical diagnosis and treatment, but also let some inexplicable diseases have roots to follow.
"But many times children are precocious, not because of genetics, but more because of external factors." Director Wang Chunlin said that precocious puberty also has a lot to do with the environment and diet structure. Among them, obesity is an important factor in causing children to precocious puberty, and excessive food intake and too good are not enough. Poultry meat, fried, large supplement foods, and out-of-season fruits and vegetables may cause hormone abnormalities in children and lead to precocious puberty.
There are two main types of precocious puberty, central precocious puberty and peripheral precocious puberty, and the difference between the two is whether the central organ that controls pubertal development is activated. During puberty, the hypothalamus, a mysterious organ, secretes gonadotropin-releasing hormone (GnRH), which stimulates the body's maturation.
If this organ is not triggered, the brain does not give orders, but due to environmental factors leading to increased hormone levels in the body, although the child has secondary sexual characteristics, but the internal and external reproductive organs are not developed, and the gonadal axis is inhibited, it is necessary to pay attention to the surrounding precocious puberty.
And once this organ is triggered, the brain issues an order, the child's body's sex hormone levels rise, secondary sexual characteristics appear, reproductive organs develop, then it belongs to the central precocious puberty - the child is "cooked" from the inside out. Central precocious puberty can be called the "invisible killer" of children's height, and it is necessary to go to a specialist for professional evaluation and treatment.