Progesterone is like this, simply put, as long as there is an ovulation, we will secrete a large amount of progesterone in our body, this progesterone will make our endometrium undergo a secretory period change, this endometrium secretory period change is to prepare for the conceived egg, so after we get pregnant, we progesterone acts on the endometrium, so that the endometrium has a very good growth environment for the conceived egg.
We progesterone during pregnancy, it is also a certain change, generally we say that after pregnancy, progesterone is better such a level, should be at a level of 20-25ng / ml, if at this level there is generally only 8% of such a miscarriage probability, if our progesterone in 10-15ng / ml this, the risk of spontaneous abortion may increase, the probability of miscarriage can reach about 30%, if our amount of progesterone drops to 5ng / ml, Basically the chance of miscarriage is more than 85%. So sometimes, patients will take the values of HCG (human chorionic gonadotropin) and progesterone at the time of pregnancy at the same time, and let us analyze it.
But one thing is this, that is, the secretion of our progesterone, it is not a continuous secretion, nor is it a relatively regular secretion like HCG, doubling every two days to two and a half days, it is secreted under the stimulation of luteinizing hormone, so its secretion is pulsed, suddenly high, and then there is a period of time not very high, and then suddenly high, luteinizing hormone, its secretion of progesterone is also pulsed secretion.
So some of our experts say that there are data showing that in a day, the amount of progesterone secretion will have a large gap, sometimes may be found at the lowest time 5ng / ml, and then the highest time can reach 40ng / ml, which measured value we take to assess whether our pregnancy is normal? So whether it is domestic or foreign experts, they sit together, such a recommendation for early pregnancy assessment mentioned, that is, it is not recommended to use progesterone as an indicator of early spontaneous abortion, or whether embryonic development is good.
But a few years ago, then has formed such a trend, so a pregnancy, in addition to checking HCG is not assured, estrogen, progesterone I must check, so sometimes will take these results to take, then as a clinician, can not completely rely on progesterone, to judge whether the pregnancy process is normal.
Because the value of progesterone is different for each time period, there is no way to accurately say that this is the possibility of miscarriage.