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After vaccination, can I directly test nucleic acids?

On January 18, according to @Xianyang Public Security, Xianyang investigated and dealt with a rumor case related to the epidemic. The offender posted in the WeChat group that "after the vaccine can not be directly used for nucleic acid, otherwise it is positive, and the vaccine after the nucleic acid does not affect", and was fined 500 yuan.

After vaccination, can I directly test nucleic acids?
After vaccination, can I directly test nucleic acids?

Image source: @Xianyang Public Security Screenshot

After the news came out, some friends sent private messages asking questions about vaccination and sampling intervals.

According to the Guidelines for the Implementation of Nucleic Acid Testing for the Novel Coronavirus for All Employees (Second Edition) issued in September 2021, it is stipulated that "those who are sampled cannot be vaccinated against the new coronavirus for 48 hours before sampling."

After vaccination, can I directly test nucleic acids?

Screenshot of the Guidelines for the Implementation of Nucleic Acid Testing for the Novel Coronavirus for All Employees (Second Edition).

In current practice, there are also some cities that have reduced the time limit to 24 hours.

After vaccination, can I directly test nucleic acids?

Image source: Screenshot of the official website of the Hunan Provincial People's Government

The reason for this provision is that the new crown virus inactivated vaccine is prepared by the wild virus through culture, inactivation and other processes, although the virus has lost its infectivity and pathogenicity, but still retains a relatively complete nucleic acid fragment.

During the vaccination process, the opening of the vaccine bottle, the extraction of the vaccine liquid, the exhaust of the syringe, the residual liquid in the syringe or the vaccine bottle after vaccination may be left in the form of liquid or aerosol on the surface of the vaccination table, wall, door handle, corridor, clothing of the vaccinator and recipient.

If nucleic acid testing is done immediately after vaccination, the nucleic acid fragment has not yet degraded, and the sensitivity of polymerase chain reaction (PCR) detection is extremely high, which may make the nucleic acid test result positive. (Planner: z_popeye, Producer: Gyouza)

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