752 AD.
After Li Baichang'an was released, he and his friend Cen Xun were guests at the Yingyang Mountain residence of another friend of Song Mountain, Yuan Danqiu, and the three of them tasted a feast and drink. One day, Li Bai sang "Reward Cen Xun Seeing yuan danqiu treating wine with poetry": "Don't be thousands of miles away, fate to drive to beckon." In the middle of the Yuan Danqiu, climbing the mountain feast Bixiao. Thinking of me about the wine, the long whistle is clear. "Life is happy, Mo Ruo put wine to make friends, when wine and poetry are intertwined, the old things and the future are difficult to distinguish, so there is a shocking "will enter the wine", its first sentence: "The water of the Yellow River rises from the sky, rushing to the sea and never returning." Writing about the coming of the great river, unstoppable, the going of the great river, the inevitable return, coming and going, soothing Providence, pinning affection, making the literati of all ages marvel, and receiving the magnificence between indulgence and convergence in life.
Suddenly remembering this famous poem was at the moment when I first met Professor Zhu Yizhen. On December 11, 2021, on the seventh floor of the International Conference Center on the banks of the Huangpu River in Lujiazui, Pudong, Shanghai, we gathered to drink wine, because we jointly attended a "Cross-Strait, Hong Kong and Macao Pharmacology Young Scholars Forum", I made an academic report on "Twenty Years of Humanistic Pharmacy - My Manuscripts, Speeches and Dictionaries" at the main venue, and Professor Zhu, the founding dean of the School of Pharmacy of Macau University of Science and Technology, rushed back to Shanghai to give a speech on "First-in-class Innovative Drug Research and Development and Molecular New Mechanism of Traditional Chinese Medicine Sources". During this period, Professor Zhu returned to his old club, Fudan University, to participate in the "Fudan Star" Entrepreneurship Competition, and personally took the stage roadshow - "Destroying the Family" Entrepreneurship, determined to create a real Chinese original drug! According to his words: accidentally won the championship. On the event, we don't know what kind of wonderful tricks yi zhen brother sacrificed, but from the report on the official website of Fudan, we learned that the runner-up is the project of Academician Zhao Dongyuan, dean of the School of Chemistry and Materials, who just received the first prize of the National Natural Science award in 2020, and I should understand how much respect the world has for innovative drugs today! Brother Yi was late to our party because of the award-winning dinner, and it is said that he was allowed to come over after drinking several cups, as evidenced by the ruddy face, which is not a lie. The law of the liquor store, late arrival is punishable, he knows this well, unequivocally, punishing himself with a small pot, let us feel very atmospheric. Next, he caught the right toast, his boldness gradually revealed, and thousands of weather slowly rose... In the face of this aura of Yi Zhen Brother, I think of Mr. Taibai who studies humanistic pharmacy at all, as a poetry immortal, Taibai cup love and talent, singing ancient and modern, Yi Zhen Brother's slightly bulging abdomen is also very similar to The Taibai of the Tang Dynasty. That night with the continuous advancement of the wine, Yi Zhen brother has been recognized as the center of the banquet, like the spiritual leader of the field, he also enjoyed this moment, the visitor did not refuse, if there is a person with red wine respect, his white fat and slightly sexy little hand will quickly pour a small glass of white wine into it, he drank first, you must also swallow this cup of bitter wine, which is the only wine place I have seen in 60 years.
At that time, the Lights of the Bund outside the window were brilliant, and the silent figures in the distance gave people unlimited reverie. The prosperity and modernity of the city is unimaginable to Mr. Taibai, but the words in his "Will Enter the Wine" constantly jump into my thoughts. The ups and downs of the opening long sentences of his poems are often copied, such as "Those who abandon me, yesterday's day can not stay; those who disturb my heart, today's day is more troublesome" ("Xuanzhou Xie ShuoLou Farewell School Shuyun"), "The man of heaven and earth, the anti-journey of all things; the time and yin, the guest of hundreds of generations." ("Spring Night Feast from Brother Peach Plum Garden Preface"). This kind of verse is wide open and wide, and only Mr. Taibai can hold it, and it has no hole in the sky. In my brief understanding of the study of Tang poetry, the poem "Will Enter the Wine" is the following poem: "Life must be full of joy, do not make the golden bottle empty to the moon." I am born to be useful, and I will come back when all the money is gone. and the final direct call: "Only the drinker keeps his name." An online article commented: "Life must be full of joy, it seems to promote the idea of timely pleasure, but it is only an appearance, has the poet ever been 'proud'?" 'The phoenix first descended the Purple Seeing Edict, and the Emperor called the Imperial Feast of the Emperor Of The Jade Pot" ("Jade Jug Yin"), which seemed to be triumphant, but also seemed to be a phantom; 'the sword was played with bitterness, and the king's door was not sympathetic'—and it did not seem to be proud, some were disappointed and indignant, but they were not depressed. The poet then affirmed life and affirmed himself in an optimistic and strong tone: 'I am born to be useful', which is a sentence that is amazing. From the seemingly negative phenomenon, a positive essence of nostalgia and desire to join the WTO is revealed deep within it. Singing for such a future, what is the cost of breaking the fee - 'a thousand gold scattered and returned' This is another highly confident and amazing sentence, which can drive money and not be driven by money, which is enough to make all ordinary people stunned. Thinking of these wisdoms that have been used through the ages and are vigilant in life, the brother in front of me has transformed into Mr. Taibai in my heart, who is full of worries, but often borrows wine to play. In the future, if we are familiar with it, if we become friends, I will advise Brother Yi to read more of Taibai's testament, understand Mr. Taibai's life experience, or deepen Brother Yi's understanding and care for himself, including a feast that can be stopped.
I first met brother Yi, but by no means a stranger, he occupied a lot of time in my heart, at least two things in my life intersected with the unconscious him, and even because he changed me, made me become me. From public information, it is known that one of the major scientific research achievements of Yi Zhen brother is to extract the active monomeric compound mother-based alkali (SCM-198) from natural motherwort, and successfully explore a new synthesis route and amplification process technology. As long as Baidu takes a look at the "chemical synthesis of mother-based alkali", we will see the large number of papers signed by Zhu Yizhen and Wang Xiaoshan, and the footprints of the two professors' teams climbing the peak of science are still faintly recognizable. Professor Wang Xiaoshan is a medicinal chemistry teacher at my university, and the old man is 80 years old this year. He is a student of Academician Wang Kui of Beijing Medical College (now Peking University Medical College), academician Liu Changxiao is his classmate, Mr. Liu's understanding of medicinal chemistry and mastery of knowledge and technology is first-class, because of the deep thinking, sometimes also reveals philosophical complexes. More than twenty years ago, I was already a member of Mr. Team, because we focused on declaring "a class of anti-tumor drugs - clinical study of neoflalcanoid acid for injection" (2009ZX09103-399) and neglected the in-depth study of the synthesis of mother herb alkali after the synthesis of mother herb, my husband and I have brought several graduate students in the direction of mother herb synthesis and pharmacology, published several papers, and declared some scientific research projects, and finally did not achieve further positive results, otherwise we may be on the same track as Brother Yizhi because of mother herb. In 2016, we saw mother-based herbamine (SCM-198) transform the industry with 150 million yuan and carry out clinical research in China and the United States at the same time, and we regretted it too late. According to the promotion of Yi Zhen's brother, this medicine may really be a good medicine! All of this has also deepened our understanding of opportunities, innovations, papers, and industries, and has taught us a very good lesson. Brother, you may know that every autumn leaf has actually experienced spring.
In 2005, Fudan University was the dean of the School of Global Recruitment Pharmacy, and was selected according to the honor of his brother. After a few years, I was interviewed by my alma mater: I could have a chance to serve as the dean of the Pharmacy College. However, at that time, the dean of the School of Pharmacy of Zhejiang University was Academician Li Lianda, and Yi Zhi brother, as the dean of fudan Pharmaceutical College, was in the limelight - discipline construction, scientific papers, impact factors, invention patents, returnee background... I was daunted and unattainable. If I take this title, how can I lead the School of Pharmacy to a place in the academic world? How to communicate with Academician Li and Dean Zhu in teaching and academic exchanges? In contrast, he was afraid to give up this only chance for promotion. After that, I put the South Mountain on horseback, my heart was as quiet as water, and I concentrated on engaging in "humanistic pharmacy" to expand the territory. Now that I think about it, as soon as I enter the Houmen, as deep as the sea, on the road of life, I know that it is difficult to give up, which is a choice that I have made that is most in line with the logical thinking of humanistic pharmacy. These two things have been entangled in my heart for more than ten years, there is nothing to talk about, no one knows, this is the reason why I paid special attention to my brother when I first saw yi Zhen and showed special eyes. But I never imagined that it would be the oldest way of expressing emotions in our nation's history to leave a deep memory and dominate me. I know that a big drink is not enough to judge the courage of wine based on one side of the conversation, and most of the wine market is full of illusions! So I asked several friends on the beach who may be familiar with the amount of yi zhen brother's alcohol, among which my Anhui compatriot Chen Jun said: We are all afraid of his alcohol, and we often drink until people turn on their horses. My good friend Brother Lu said: Very powerful, we must let him have fun. ... In this way, Brother Yi Zhen is not a waste of wine, it is where the strength lies. Correspondingly, his talent, these two things often go hand in hand, complement each other, the tide rises, each other's confidence, talent I will say in another article. Or talk about his wine that night, to tell the truth, even if the wine is high, he has not seen his aphasia, he is hovering there, there is a kind of momentum that can get close to me, indicating that he has a strong ability to control himself, which requires super will, this proportion among humans is very small, Mr. Taibai is one of them. People have always regarded the unruly contempt of the powerful as a portrayal of Mr. Taibai's upright character, but he is drunk and clear-hearted. One day, the noble concubine Niangniang, tired of listening to the clichés, Tang Taizong ordered people to find the drunken Taibai, asked him to fill in the new words, he actually performed a paragraph of "Li Taibai is drunk, GaoLishi takes off his boots", with the power of wine, he actually waved four seven-piece "Qingping Tone", the first sentence is: "Yun wants to dress and flowers want to look" These seven big words, Guifei is happy, everyone can enjoy the aesthetic sense of the high, but no one can give how high the "impact factor" of this verse from ancient times to the present is? How often is it cited? How many women are inside? Leading the gaze of how many look through the autumn water? However, more than 330 scientific papers by Brother Yi, cited more than 12,300 times (H index 63, i10 index 199 Google Scholar 2021.10.20), are very impressive, approaching and challenging Mr. Taibai's poems and distant places with a tangible number.
Moth was outside, and near the front of the bottle. What is the courage of the brave, and what is the feeling of the scholar? On that night on the Bund, I saw the extraordinary behavior and academic flair of a person engaged in pharmaceutical research, and I would like to report to the world with a different brushstroke: In my heart, I am as interesting and admired as Mr. Taibai!
2021.12.29 On the mizumi
Acknowledgements: Web text, web graphics
About the Author
Xia Ye, real name Xia Lunzhu, professor, chief pharmacist, master tutor of pharmacology and pharmacy of Anhui University of Traditional Chinese Medicine, supervisor of the First Affiliated Hospital of Anhui University of Chinese Medicine, engaged in humanistic pharmacy, clinical pharmacy, pharmaceutical education, pharmaceutical management and new drug creation study and research for 40 years. He is currently the vice chairman of the Anhui Pharmaceutical Association, a member of the Evidence-based Pharmacy Professional Committee of the Chinese Pharmaceutical Association, and the chairman of the Hospital Pharmacy Professional Committee of the Anhui Pharmaceutical Association. He is the deputy editor-in-chief of China Pharmacy magazine and the editorial board of nine pharmaceutical academic journals. Undertake the preclinical research of three major new drug creation projects such as "Clinical Research on Neoflocyticki Acid for Injection" (a class of new drugs) of the Ministry of Science and Technology of the People's Republic of China. Participated in 12 research projects at the national, provincial and ministerial levels such as the National Natural Science Foundation of China. He has published more than 100 academic papers. He is the chief editor of five academic works and university textbooks such as "Supercritical Extraction and Pharmaceutical Research", "Evidence-based Chinese Medicine", "Humanistic Pharmacy Essays", and participated in the editing of more than 10 books. Gu Fang's philosophical science and pharmacology marginal research, self-appreciation grammar and calligraphy inner desolation. Expectations of academic circles: pharmacy lips and teeth, humanities deep throat.
Source: China Pharmacy Online Edition, No. 4, 2021