How to reverse aging? How to rejuvenate?
Everyone has always wanted to explore the mysteries of aging.
In ancient times, many places wanted to maintain eternal youth and return to old age, and even many emperors paid blood for this, either alchemy or sending people to find "immortals".
But either way, the end result is the same, no one really gets a good way to stay young forever, and everyone will go into the process of aging.
Life, old age, illness and death have always been a natural law, all people are the same, can not escape aging, all organs and cells will enter this complex process of change.
According to the data of the seventh national census just released, the population over 60 years old in China has reached 264 million people, accounting for 18.7% of the total population.
According to the United Nations definition, if the number of people over 60 years old in a region reaches more than 10% of the total population, it is considered that the region has entered an aging society.
Obviously, according to this standard, China has entered an aging society, and there are more and more elderly people.
However, the dream of eternal youth is still unchanged, and there are still many people who want to know how to rejuvenate.
Is there really a way? In the past, everyone thought that blood was the key to aging, and if the blood of young people was injected into the body of the elderly, it would make the body slowly become young.
At present, this kind of thinking has no scientific basis, and it is very inhumane to hear, but will this practice really not succeed?
Not.
In the United States, researchers have really done experiments that have found that if young blood is injected into the body of an elderly individual, it can really make a lot of cells and tissues younger.
Is this reliable? Can we use it?
Today we will take a look at it together, will the blood of young people make people "reverse aging"?
@Rehabilitation Therapy
Rejuvenation has always been the common pursuit and yearning of mankind, not only in our country, but also in foreign countries, there are many scholars exploring the mysteries of life sciences.
At the University of Pittsburgh in the United States, some people have studied aging, and they want to confirm that young blood can reverse aging.
The study was published in Nature-Aging, and it's clear that as a journal owned by Nature, this article is still very reliable and has been recognized by scholars in the industry.
However, it should be noted that the subject of the experiment here is not a human, but a small mouse.
We all know that in the process of aging, whether it is a whole or a single, cells are slowly getting older, especially the ability to repair damage, is gradually degrading, in many cells, muscle cells change is very large, will slowly weaken, become atrophied, and the ability to repair is not as good as before.
The researchers mainly looked at the muscle cells of the mice.
First, they drew blood from some young mice, and then removed the regular blood cells and clotting factors, which was all the rest.
Then the collected serum was directly hit into the injured muscles of the elderly mice to see if there was any change in their muscles.
The results confirmed that the muscles of the mice who received the young serum improved significantly, especially the regenerative function of the muscles was significantly improved than before.
Which ingredients cause this?
In further experiments, it was found that if the extracellular vesicles in the serum are removed, then this improvement disappears, so the scientists came to a crucial conclusion:
Extracellular vesicles are the key to rejuvenation.
But what are extracellular vesicles?
Extracellular vesicles are actually endogenously produced membrane-bonded vesicles, which have a phospholipid bilayer that contains many other molecules.
Depending on the origin of cells and biological development, extracellular vesicles are divided into many types, such as common microvesicles, exosomes, and apoptotic bodies.
However, in previous studies, extracellular vesicles have been ignored, and even once thought to be waste products produced by cells, but as the research progresses, more and more scholars feel that this substance is useful, especially for the life sciences.
The most important of these substances are exosomes, which can be secreted by platelets, lymphocytes, and even many other kinds of cytokines, and are easily detected.
The person in charge of the study believes that the extracellular vesicles in such plasma can encode the genes related to anti-aging proteins, and then transmit this signal to muscle tissue cells, so it can promote the regeneration of muscle cells.
And previous studies have also confirmed that young blood can improve the cognitive ability of old mice, making him a little more "smart".
Therefore, seemingly very unreliable "blood transfusions" are likely to become a good way to fight aging.
But is this method reliable? How long will it take for us to use this anti-aging treatment?
How long will it take to use it? In fact, this treatment may take a long time.
It can be called a "lifetime".
Although we have found some ways to improve the state of cells, such as extracellular vesicles, which components are specifically and how effective are these ingredients? How effective it is, in fact, needs to be further studied.
As mentioned above, intracellular vesicles are actually a complex, which contains many kinds of components, and we still have no good way to distinguish which ingredient has the most significant effect and who plays the role.
And even if specific improvement substances have been found, there are still many studies that need to be improved, such as whether this operation can be applied to adults, and will there be other adverse reactions and discomfort?
After all, no one wants to be a guinea pig, and no one wants to try a new treatment.
In addition, ethical issues are also very important, where does the young blood come from? How much does it cost to get this blood product?
Just like a new drug, just developed to clinical application, it takes many years, or even more than twenty years of ups and downs, and finally precipitated is a good drug that can be used.
In the face of aging, the most important thing is to actively prevent it, we can't stop aging, but we can make aging slower.
How do you do that?
A person's life expectancy may seem uncontrollable, but in fact, many bad habits will bring negative effects, so how can we make ourselves healthier and make ourselves live longer?
Here are 4 suggestions for you, all of which are reliable and good suggestions:
1. Mood is important.
Everyone's mood is different, some people are very grumpy, some people have a very gentle temperament, but in some studies it has been found that the kinder the person, the longer the life expectancy.
Therefore, if you want to open something, don't drill the tip of the bull's horn.
2. Sleep quality.
Do you sleep well?
When sleeping, it is the best period for the body to repair itself, such as when the brain sleeps, the brain can remove the waste, and people who stay up late for a long time or sleep poorly will obviously feel the fatigue of the body and easily fall into the trap of health.
3. Control weight.
Whether it is male or female, weight is a big problem, for most people, after entering old age, the stomach will become larger and larger, so weight loss has always been a long way to go.
Gaining weight can easily lead to other chronic diseases, such as high blood pressure, diabetes, and even hyperlipidemia.
Controlling your weight well is a great way to live a long life.
4. Appropriately increase physical activity.
Life lies in exercise, if you have the conditions or time to increase the amount of exercise for yourself, even if it is to do housework, even if it is to go out for a walk, as long as you do not sit or lie down, the strength of the muscles will be maintained, and even increased compared with before.
Can transfusing young blood to the elderly really reverse aging? Current experiments have confirmed that in small mice, this thing is feasible, especially in muscles, and the effect is obvious and can be seen.
But is this also true of tissues and organs other than muscles? Obviously, not necessarily.
The research has yet to continue, and there are still many questions that have not been explained clearly, not only in mice, whether it can be applied to humans, it remains to be further explored, and scientists have not given a clear answer.
But we already have a breakthrough point, there are many researchers are looking for ways to conduct similar research and discussion, I believe that in the future, human beings will one day understand the mystery of aging.
But before that, we still focused on preventing aging and delaying the aging process.
@Headline Health #Rumor Zero Project ##Doraemon Super Group ##健康明星计划 #
bibliography [1] Sahu, A., Clemens, Z.J., Shinde, S.N. et al. Regulation of aged skeletal muscle regeneration by circulating extracellular vesicles. Nat Aging (2021). https://doi.org/10.1038/s43587-021-00143-2 Luo Yaxin,Bi Haoran,Chen Xiaoxu,Yang Kun. Mesenchymal stem cell-derived exosomes and regenerative medicine: the future of clinical application of cell-free therapy[J].China Tissue Engineering Research,2020,24(19):3055-3062. Shi Xiaoming. Research progress in geriatric epidemiology in China[J].Chinese Journal of Epidemiology,2021,42(10):1713-1721.
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