Pacemakers are life-saving medical devices that can be used to control and correct different forms of irregular heartbeats. This small device can be implanted in the chest to maintain the rhythm of the heart, but the way it regulates the rhythm of the heartbeat is very different from the natural beating of the heart.
Scientists are now planning to test a new device that can more accurately simulate this natural time. After successful animal studies, this "revolutionary" pacemaker is expected to be further tested in New Zealand this year.
A team of researchers at the University of Auckland has developed a "bionic" pacemaker called Cysoni, a device that responds to signals from the body in real time. This device will monitor breathing and change the heart rate accordingly, rather than ticking at a constant rhythm.
The researchers explain that if you analyze your heart rate, you will find that your heart rate is linked to your breathing. It rises on inhale and falls on exhalation, which is a natural phenomenon for all animals and humans.
Inspired by this, researchers began researching the possibility of developing a new type of pacemaker 20 years ago to treat patients with heart failure. Since the heartbeat of people with the disease is not regulated by breathing, the scientists decided to see if there would be benefits in putting heart rate variability back into animals with heart failure.
The new bionic pacemaker aims to recover heart rate variability by monitoring the lungs and detecting the electrical signals produced when the body breathes. In this study, pacemakers used precisely timed pulses as needed to speed up and slow down the heart.
The device saw positive results in rats, so the researchers turned to sheep, and now they believe they have found a way to reverse heart failure.
This study showed that introducing natural changes in the heartbeat can improve the heart's ability to pump blood through the body. The researchers said that the heart output in the study was improved by 20 percent, which is actually the heart's ability to pump blood through the body, and 20 percent is a big number.
Researchers are currently planning to use the device for humans and are already recruiting patients for the trial, which will start in New Zealand later this year.
A related research paper titled Reverse re-modelling chronic heart failure by reinstating heart rate variability was published in Basic Research in Cardiology.
Forward-looking Economist APP Information Group
Original text of the paper:
https://link.springer.com/article/10.1007/s00395-022-00911-0
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