How does statin lower blood lipids?
Speaking of Statin's name, there should be no one who doesn't know it, right? This is a drug that treats high blood lipids.
Human blood lipids have the function of providing energy, building cell structure and synthesizing hormones, etc., when the lipid metabolism is abnormal and disordered, it is easy to cause atherosclerosis, if not treated in time, it can cause cardiovascular and cerebrovascular diseases.
Statins can reduce LDL cholesterol in blood lipids (which is not good for the human body), increase HDL cholesterol (beneficial to the human body), and remove garbage from blood vessels, thereby achieving the purpose of regulating blood lipids.
Statins are currently the most effective lipid-lowering drugs, which are widely used in clinical practice, not only can reduce cholesterol, stabilize and reverse plaque, but also delay the development of atherosclerosis and reduce the risk of cardiovascular and cerebrovascular diseases.
Statins can not be eaten more, easy to have side effects?
As the saying goes, it is a drug that has three points of poison, statin is no exception, once you take statin for a long time, you may also have the following 3 side effects:
: Muscle soreness and weakness
Patients who take statins for a long time are likely to experience the side effects of muscle soreness and weakness. Therefore, it is best for patients to check their own creatine phosphate kinase before taking statins, and then check the condition of phosphocreatine kinase after taking statins for a period of time.
If muscle aches and weakness occur during this time and creatine phosphate kinase exceeds the normal range by more than 10 times, the drug should be discontinued immediately.
: Changes in liver function
Some people who take statins experience elevated liver enzymes, and after stopping taking them, some people's liver enzymes return to normal, but some people do not return to normal levels.
Liver enzymes should be checked before use, within 12 weeks after treatment, or after increasing the dose, and then periodically every 4 weeks during use.
If the liver enzyme is abnormally elevated, close monitoring is required, if the liver enzyme is elevated at 3 times the normal level, immediately stop the drug for medical treatment. Alcoholics, cholestatic hepatitis caused by impaired liver function, drug intolerance, and poor metabolism should be used with caution.
: May induce diabetes
Statins may induce hyperglycemia and diabetes by inhibiting mechanisms such as insulin secretion and reducing muscle energy expenditure, and the overall benefit of statins for vascular disease is 9:1 in ratio to the risk of new-onset diabetes.
Statins are far more protective of cardiovascular disease than the new risk of diabetes, but it is important to check blood glucose levels regularly during use.
But overall, compared to the side effects of drugs, doctors recommend that "as long as there are no contraindications, patients can tolerate, long-term use of statins is to inhibit the progression of atherosclerosis, is the most important drug to prevent the recurrence of cardiovascular disease." ”
What do I need to pay attention to when taking statins?
Not all hyperlipidemia should be eaten statins
(1) Elevated HDL is a good thing, so HDL does not need to eat statins; and eating statins is also to elevate HDL.
(2) Simple triglycerides are elevated, and statins are not preferred, if you want to lower triglycerides and take drugs, fibrate lipid-lowering drugs are preferred.
Check your body regularly
There is also a long-term medication population, the need to regularly check the body, so that you can find out in time whether the drug brings some side effects to the body, timely adjustment.
When you need to take drugs in your life, you must follow the doctor's instructions and instructions to prevent the medicine from being symptomatic, and the effect of the treatment will not bring a series of side effects to the body.
Medication course
For patients who already have cardiovascular and cerebrovascular diseases (such as stroke), or patients with high risk factors (such as diabetic hypertension), even if the blood lipid level is within the normal range, it is necessary to take such drugs under the guidance of a doctor to prevent the recurrence of the disease, and long-term adherence to the drug can be effective.
Tips:
It is precisely because his stinging drugs have a good lipid-lowering effect, so for anyone diagnosed with ischemic cardiovascular and cerebrovascular diseases, such as: coronary heart disease, angina, myocardial infarction, cardiac bypass, cardiac stents, serious unstable carotid artery plaque, cerebral infarction and other diseases, must be under the guidance of a doctor to take statin drugs for a long time, can not be stopped casually, the drug must be approved by the doctor.