There is a relative, there is gout for many years, many times a year, when the pain attack, can not sleep at night, every time to hang the emergency department at night to relieve pain, usually drunk as fate, persuade him not to drink, but also swear that liquor is okay, beer I do not drink. This kind of self-deception is incomprehensible to ordinary people, and can only say that he is in pain and happy.
The weather is cold, and many people say that there is no trouble that cannot be solved by one hot pot, and if one meal cannot be solved, then two meals. Hot pot, beer, barbecue, to satisfy the appetite, do not know that the metabolites in the body have undergone tremendous changes, the most obvious is uric acid. Many people never take high uric acid seriously, thinking that they have never had gout, and it is no problem to eat and drink. You know, any problem has a quantitative change to a qualitative change process, not painful now, does not mean that the future is not painful, does not mean that there is no impact on other organs.
How did gout come about?
Gout is a joint inflammation caused by abnormal purine metabolism in the body, excessive uric acid. Uric acid is a metabolite of the human body, under normal circumstances, the production and excretion of uric acid in the body is a dynamic balance, so that the level of uric acid in the serum is maintained within the normal range, when the uric acid production is too much or excretion is reduced, this balance will be broken, the level of uric acid in the blood will increase, and uric acid crystals will be precipitated and precipitated in the joint bones, causing joint swelling and pain, thereby inducing gout arthritis. If arthritis recurs, tophi may also form and cause bone destruction, joint deformities, and even the inability to walk.
More seriously, gout is only a superficial symptom of high uric acid, and long-term high uric acid can cause some problems with other organs throughout the body, especially the kidneys.
1. Uric acid deposition in the kidneys will cause gouty nephropathy, will form uric acid kidney stones, a very small number of serious cases will develop renal failure, uremia.
2. High uric acid will also stimulate the blood vessel wall to cause atherosclerosis, when the blood vessels harden for a long time, it will make the incidence of cardiovascular and cerebrovascular diseases (hypertension, stroke) significantly increased.
3. High uric acid will also damage islet B cells, causing insulin function to be destroyed, thereby inducing and aggravating diabetes.
For people with simple high uric acid, if you don't want to wait for gout to come, then you should do one thing well, that is, to lower uric acid. You should pay attention to the following points when lowering uric acid:
1. Avoid the intake of high purine foods
High purine foods include seafood, animal offal, hot pot, soup, meat these are all high purine food, excessive intake can easily lead to purine metabolism disorders, so that uric acid increased.
2. Absolute prohibition of alcohol
People who have gout should not drink less, but absolutely abstain from alcohol, not only beer, all sweat, all types of alcohol, including alcoholic beverages, should be prohibited. Alcohol not only inhibits the excretion of uric acid, but also promotes the breakdown of purines to raise uric acid.
3. Drink less sugary drinks
Sugary drinks often contain a lot of fructose, and fructose will promote the production of endogenous uric acid, so try to drink less sugary drinks.
4. Drink plenty of water
Patients with hyperuricemia and gout should drink more water to promote the excretion of uric acid.
5. Maintain a normal work and rest and avoid staying up late frequently
Staying up late is a cause of gout attacks, long-term irregular work and rest, will make the body metabolism disordered, renal blood vessel contraction, but also make uric acid excretion reduce.
20% of the human body's uric acid is ingested through food, 80% comes from the metabolism of purines in the body, so in addition to the strict low-purine diet, if uric acid is still at a high level, then it should be a regular and reasonable use of uric acid-lowering drugs, and the current recommended drug is nonvestist.
Patients with gout with a blood uric acid of more than 360 umol/L and severe gout patients with a blood uric acid of more than 300 umol/L (recurrent attacks, tophi, renal impairment, etc.) must take drugs that lower uric acid.
For patients with simple hyperuricemia without gout symptoms, if the uric acid is still more than 540umol/L after six months of lifestyle adjustment, it is necessary to take uric acid-lowering drugs and try to control it below 420umol/L.