When it comes to metabolic diseases, the first thing that comes to mind is diabetes and hyperlipidemia.
As everyone knows, in recent years, due to the change of diet and living habits and other aspects, there is a metabolic disease incidence rate is increasing year by year, the total number of people with diseases has reached nearly 120 million people, accounting for 10% of the total population of the mainland, and the total number of diseases has even exceeded diabetes.
Because of this, it has become the fourth highest after the three highest diseases, which are: hyperuricemia!
Under normal circumstances, the uric acid in the human body is about 1200 mg, and the daily new production and excretion of uric acid are about 600 mg, which is in a state of dynamic equilibrium.
However, once the body produces too much uric acid, or abnormal uric acid metabolism, it will cause blood uric acid to persist in the body, and then develop hyperuricemia.
According to the current clinical data, under the premise of a normal purine diet, if the blood uric acid level test on an empty stomach is carried out on different days, the blood uric acid level in men is higher than 420 μmol/L, and the female is higher than 360 μmol/L, which can be diagnosed as hyperuricemia.
Because most patients with hyperuricemia do not have any symptoms in the body, but the disease is found in a chance physical examination, so many people do not pay too much attention to it.
As everyone knows, hyperuricemia seems to have no symptoms at present, but it has great harm. If left unchecked for a long time, the following types of diseases may find themselves:
1. Gout
After years of clinical research and investigation, gout belongs to a crystal accumulation joint disease, and hyperuricemia is the basis of the onset of gout. Of course, this is not to say that as long as the blood uric acid level exceeds the standard, it will cause gout attacks.
In clinical view, gout will only occur after the blood uric acid level continues to exceed the standard, and its precipitated urate crystals accumulate in the joint and cause damage. In general, the more serious the blood uric acid level exceeds the standard, the higher the likelihood of developing gout in the next 5 years;
2. Hypertension
According to the current epidemiological research reports, the high and low levels of blood uric acid are clearly associated with the incidence of hypertension, which is an independent risk factor for primary hypertension. For every 59.5 μmol/L increase in blood uric acid levels, the relative risk of hypertension increases by 25%.
In mainland china, nearly 90% of patients with primary hypertension have combined with hyperuricemia. Only 30% of patients with secondary hypertension have the disease, suggesting a correlation between hyperuricemia and essential hypertension;
3. Diabetes
First of all, we must understand that the pathogenesis mechanism of diabetes is that the patient's islet function is damaged and the cells are not sensitive enough to insulin. Related studies have pointed out that long-term hyperuricemia can destroy the function of islet β cells, which in turn causes diabetes to appear.
Not only that, the onset of hyperuricemia and type 2 diabetes are closely related to long-term unhealthy eating habits and living habits, and the prevalence is naturally relatively high under the common physical environment.
All in all, hyperuricemia is currently asymptomatic, just because it is harmless. In addition to the three major hazards mentioned above, the study also found that it is closely related to cardiovascular and cerebrovascular disease, hyperlipidemia, coronary heart disease, kidney damage, etc. The longer it is left unchecked, the greater the later damage.
Therefore, everyone should recognize the harm of hyperuricemia, and once diagnosed, it is necessary to actively cooperate with doctors for conditioning.