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Chinese scientists have made a blockbuster discovery: orange extract, inverting 50.57% of the life clock

author:Dr. Zhou said Chinese medicine

"An orange and five flavor medicines, the skin and flesh core are all treasures."

Throughout the autumn and winter, the citrus family occupies an extraordinary place on the fruit shelf. But when eaten, the sticky aromatic oil on the hands, the white silk wrapped in the flesh, and the slightly bitter white seeds in it are often distressing. In fact, they are not small.

A domestic scientific study found that one of the extracts can not only resist the body's oxidation, but even significantly delay aging. The "auspicious fruit", which has been praised by the people for thousands of years, why is it so powerful?

Chinese scientists have made a blockbuster discovery: orange extract, inverting 50.57% of the life clock

01 The little orange made a great contribution, turning back 50.57% of the life clock

A paper published in Nature by Shanghai University of Traditional Chinese Medicine found that the addition of a lightly bitter Nomilin extract in citrus peels and white seeds can not only improve the oxidative resilience of twilight mice, but also significantly prolong the average survival time.

During the experiment, the researchers tested the anti-aging performance under three types of triggers, and two of them had outstanding results.

Chinese scientists have made a blockbuster discovery: orange extract, inverting 50.57% of the life clock

In the D-galactose environment, mouse brain cells will accelerate apoptosis, and the oxidative damage of the body will also be greatly improved, which is closely related to the decline of cognitive function caused by aging. After the treatment of the above extracts, the oxidation and apoptosis of the test subjects were reversed, and the health of young people was maintained.

Under the induction of doxorubicin environment, the experimental subjects not only decreased their exercise level, but also suffered varying degrees of damage such as atrophy and fibrosis of the liver and myocardium, and accelerated the aging of the body. After the treatment of Nomilin extract, the above indicators were improved, and the average healthy life span of Progeria mice was also extended by 50.57%.

Chinese scientists have made a blockbuster discovery: orange extract, inverting 50.57% of the life clock

Why does the ordinary citrus extract have such a powerful experimental expressiveness? The scientific research team combed through the previous literature and found that it can enhance the expression of detoxification genes.

Follow-up experiments have shown that there is a pregnane X receptor (PXR) in mice and other mammals that can be activated by it, thereby reversing aging problems such as impaired motility, neuronal apoptosis, and liver inflammation. Theoretically, Nomilin can actually activate this target to achieve the coveted "rejuvenation of youth"?

02 10 times a day is stressful, what else can I do with "longevity"?

According to the above experimental data: 60kg adults need to take 243mg of extract per day to achieve the same effect. However, with the conversion of the rich content of mandarin oranges, it can only be achieved by eating about 13 per day. A large number of citrus fruits are not only difficult to digest, but also bring side effects such as increased blood sugar and fire.

In fact, research on intervening substances is no longer a niche thing. For example, Timecure's healthy aging management service, which is currently civilian in China, has formed a personalized nutritional product production line containing "more than 400 kinds of high-purity raw materials", and under the guidance of 3-5 doctoral-level people, the intervention plan for each body's aging cause is matched.

Chinese scientists have made a blockbuster discovery: orange extract, inverting 50.57% of the life clock

At the same time, anti-aging substances such as citrus extracts are relatively simple for "prolonging the healthy life span of the body and reversing the youth level". Among the human aging markers published by the authoritative academic journal "Cell", there are currently 12 major items known to include apoptosis, telomere wear, mitochondrial dysfunction, etc., and it is not easy to intervene comprehensively.

Logging on to the official website of Timecure service appointment found that more than 500,000 aging equipment intervention equipment such as hyperbaric oxygen, cryotherapy, and floating tanks, which are favored by stars such as Ronaldo and James, have also become one of the means that national users can access in their offline centers.

Among them, the research published in "Aging" by Israeli scientists confirmed that "hyperbaric oxygen therapy" can significantly reverse the aging phenomena of the body such as pigmentation and muscle grip decline, and even make telomeres regrow by more than 20% and apoptotic cells remove by 37%.

Chinese scientists have made a blockbuster discovery: orange extract, inverting 50.57% of the life clock

In addition to the above two types of mainstream interventions, overseas research on aging biomedicine is also accelerating, such as the Mayo private clinic in the United States and the same medical institution in Ginza, which are still high-end resources that are difficult for ordinary people to reach. In the above-mentioned official website reservation project of the Timecure service, the docking of such scarce resources is included.

03 Life technology blowout, the era of 100 years is coming?

The blowout of advanced life science and technology not only prolongs people's healthy lifespan, but also greatly improves the quality of life.

Previously, the Nobel Prize-winning "gene scissors" technology is being used to correct once-intractable genetic diseases such as cystic fibrosis and severe immunodeficiency. The "brain-computer interface" technology led by Musk has been implemented by the team of Zhejiang University in China, and a 72-year-old man with quadriplegia can eat independently and shake hands through a robotic arm.

"With the development of geriatric intervention technology, the vast majority of people born in the 21st century are expected to exceed 100 years old", a study from Johns Hopkins University seems to depict a more desirable future for human beings!

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