The 2024 Zhongguancun Forum Global Women in Science and Technology Innovation Forum was recently held in Beijing, where Chinese and foreign scientists from different fields gathered together to share their love and perseverance for scientific research, discuss the full release of women's scientific and technological potential in the new round of scientific and technological revolution and industrial transformation, and share the responsibility and mission of promoting global innovation and development. The forum not only focused on the outstanding demeanor and outstanding achievements of women in the field of cutting-edge science and technology, but also released the "100 Women's Scientific and Technological Innovation Achievements" since the implementation of the Women's Action in Science and Technology Innovation. The research results of five female scientists in our city were selected, let's get to know them together.
Wang Yan
President of Tianjin Eye Hospital Affiliated to Nankai University
Presentation of research results:
In view of the fact that myopia and other refractive errors have become a high incidence and urgent problem to be solved in the mainland, he led the team to complete the first minimally invasive refractive surgery in the mainland after more than 20 years of cross-innovation research and breakthroughs, and successfully promoted and applied it to the whole country, and has completed 5 million cases in the country. Successfully established optical models such as micron-level human eye color aberrations to fill the gap in the world. With the help of biomechanics and other new methods, he has made new breakthroughs in the diagnosis and treatment of diseases, and has won more than 20 key projects of the Ministry of Science and Technology, the National Natural Science Foundation of China and provincial and ministerial funds. For the first time in the world, the application of AI technology to assist precision treatment has been awarded the "Top Ten Advances in Ophthalmology in China", and the diagnosis rate of keratoconus with the help of artificial intelligence ranks first in the world, significantly improving the accuracy and safety of diagnosis and treatment. Significant social and economic benefits have been achieved.
Donna
Professor, Tianjin University of Science and Technology
President of Tianjin Women Science and Technology Workers Association
Presentation of research results:
The project develops key technologies and equipment for spherical anti-consolidation edible salt, and breaks through the problem that edible salt is easy to consolidate. Research and development of multi-variety, high-quality edible salt production technology and equipment, products to meet the food processing process for nutrition, flavor and taste and other multi-dimensional needs. Develop the deep impurity removal technology of medicinal inorganic salts, establish the only whole industrial chain of medicinal inorganic salts in China, and realize that medicinal salts are among the international high-end markets. The project has been authorized 19 invention patents, formulated 4 standards, and transformed into a number of leading enterprises in the salt industry, with an additional output value of 4.006 billion yuan and an additional profit of 903 million yuan in the past five years, which has effectively promoted the scientific and technological progress and industrial upgrading of the mainland salt industry.
Yin Haifang
Professor, Tianjin Medical University
Presentation of research results:
There are problems in the clinical application of biological drugs, such as low efficiency, poor targeting, and limited biocompatibility. In this project, the phage display technology was innovatively used for the screening of exosome-anchored peptides, and a new method for exosome functionalization and capture based on anchored peptides was created. A series of tissue-targeting peptides were obtained by combining the created tissue in vivo section platform with phage display technology, which provided a new vector for targeted drug delivery for locomotor system genetic diseases and liver cancer. From the perspective of energy metabolism and stem cell proliferation and differentiation to promote nucleic acid drug uptake, a hypothesis was proposed and verified that nutrients can promote drug transport and uptake through metabolic capacity and muscle stem cell proliferation and differentiation. A new theory was established that hexose and glycine could be used as "non-classical" drug delivery vehicles.
Sun Hongwen
Professor of Nankai University
Presentation of research results:
Since 2012, the project team has continuously undertaken national-level projects, and has made several important discoveries on scientific issues such as human exposure pathways, exposure loads, metabolic transformation characteristics in vivo, and their adverse health effects and mechanisms, and improved the understanding of human exposure pathways and in vivo transformation pathways of new pollutants. The metabolic transformation characteristics of new pollutants were clarified, and a new method for exposure load assessment and a new law of transport in vivo were proposed. Revealing the health risks of new pollutants to high-risk populations. The results have been cited and introduced by authoritative academic journals such as Science, and have been widely affirmed and referenced by peer experts. The results have also been adopted by international organizations and regulatory bodies such as the World Health Organization and the European Union Scientific Committee on Consumer Safety, providing strong support for chemical management and human health protection.
Yan Beibei
Professor, Tianjin University
Presentation of research results:
In view of the bottleneck of high energy consumption, serious secondary pollution and low conversion efficiency in the traditional tar treatment process, tar microwave cracking technology and equipment were developed to achieve low energy consumption, clean and high-efficiency tar cracking conversion. In order to solve the problems of low calorific value, variable composition and impurity of biogas, and the instability of combustion caused by impurities, and the difficulty of controlling pollutants, flameless combustion technology and equipment with fuel adaptability were developed to realize the clean and stable combustion of biogas. In view of the source control requirements of the gasification process and the scientific design requirements of advanced gasification combustion devices, a system evaluation and optimization software was developed to achieve accurate adaptation to the preparation of multi-source biogas.
Source: Development Department of Tianjin Women's Federation
Editor: Wen Fei
Proofreading: Late winter