The success of the transplant is a very gratifying thing, after experiencing ovulation, egg retrieval, transplantation, and finally cultivating positive results. Many of our patient friends are happy, and they will also share this good news with their friends, and this sharing is a problem:
Why on the same day of transplantation, me and her HCG value are more than doubled;
Why did she have a urine test (+) 5 days after the transplant, and I only tested it 10 days after the transplant...
01
The degree of development varies
IVF is transferred on the same day and blood HCG is tested on the same day, but its levels vary, the first possible reason is that the degree of development of embryos at the time of transfer is different. Embryos that develop longer have more trophoblast cells and higher blood hCG levels.
Example: Ms. A and Ms. B are transferred on the same day, Ms. A transfers a fissile embryo that develops to day 3, and Ms. B transfers a blastocyst that develops to day 5. Half a month later, both became pregnant.
Who has a higher blood hCG value? The embryos on days 2-3 are in the cleft phase, with only cleft bulbs and have not yet differentiated into trophoblast cells, while blastocysts are embryos that have developed to the 5th day and have differentiated into a trophoblast layer. Therefore, if it is the same day of transplantation, the transplanted blastocyst can be said to have "won at the starting line", so the blood HCG level on the day of the test will look higher.
02
Causes of single and multiple tires
The blood hCG value of twins in multiple pregnancies will generally be higher than that of singletons, but this does not mean that a high blood value is necessarily a twin. At present, the diagnosis of single twins, B ultrasound is still the gold standard, and it cannot be completely considered that high blood value is twins.
03
Differences in implantation times
One theory is that even embryos of the same degree of development may have different timings of implantation into the uterine lining, and that if the embryo implants earlier and secretes more HCG earlier, the HCG detection value will be higher.
04
Individualized differences in the rate of embryonic development
For embryos, due to different specific developmental potentials, there are also possibilities such as slower division of trophoblast cells and obstruction of the process of invading the inner membrane. The rate of development of each embryo cannot be exactly the same, just as all first-grade children will have objective differences in height, weight, learning ability and athletic ability.
Therefore, the difference in HCG values between expectant mothers is very large, and it is meaningless to compare them with each other. As long as the embryo develops and grows smoothly, all aspects of the test indicators are within the normal range. Expectant mothers should not worry too much about anxiety, maintain a relaxed and happy mood, and their children can develop healthily.
Joy to share