HAO YUN WO
Blastocyst culture has many benefits
We all know that the difference between IVF and naturally pregnant babies is that IVF is in vitro fertilization, which is transplanted back into the mother's womb after 3-5 days of culture to continue to develop. We generally choose the 3rd day (fissile transplantation) or the 5th day (blastocyst stage transplantation) at the transplant time. Blastocysts are one of the process stages in the development of the embryo.
Blastocyst culture is a method of selecting good embryos, some embryos can not develop to the blastocyst stage, so that the embryos are further screened, improving the chances of pregnancy.
In the fresh transplantation from January to September 2021, the clinical pregnancy rate of the blastocyst stage (day 5) transplant was higher than that of the cleft stage (day 3), with a difference of nearly 20%. The clinical pregnancy rate of blastocyst stage transplantation was as high as 64.3%.
PART#01
Advantages of choosing blastocyst culture
1. The transplanted blastocyst and the endometrial implant window are more synchronized, more in line with the physiological implantation time window, and the uterine contraction is significantly weakened, which is conducive to the "landing" of the embryo in the uterus and improves the chance of the embryo implanted in the mother's uterus.
2. Shorten the direct time interval between transfer surgery and embryo implantation, reduce the chance of embryos being excreted from the body, and increase the possibility of pregnancy.
3. Blastocyst culture of low-scoring embryos in the cleft stage (such as grade III, IV embryos, non-2PN embryos, it is not recommended to transfer and freeze), embryos with developmental potential can be screened out, and some abnormal embryos and embryos with low developmental potential are eliminated, so that the embryos available for transfer are further optimized, and the pregnancy rate is significantly improved.
4, multiple pregnancy to the mother and the fetus are a great health risks, single blastocyst transplantation in order to ensure the chance of pregnancy at the same time can also reduce the rate of multiple pregnancy, can avoid the risks of subsequent fetal reduction surgery.
Blastocyst transplantation has so many benefits, but it is not suitable for all patients. Because blastocyst culture also has risks, one of the biggest risks is that if there is no blastocyst formation during blastocyst culture, the patient will face the cancellation of the transfer, that is, there will be no embryo transfer in this egg retrieval cycle.
Because blastocyst culture can only do is to make the embryo transferred back to the mother's womb more preferred, and the embryo itself can not be changed from bad to good in culture. Some experts believe that due to the superior environment in vivo and the reduction of in vitro culture time, transplantation into the body during the fissure period may be more conducive to the development of stunted or morphologically poor embryos.
Blastocyst culture has many benefits and significantly improves the pregnancy rate. However, blastocyst culture is also risky and is not suitable for all patients. Follow the advice of physicians and embryologists and work together to choose the most advantageous path,
I believe that a good pregnancy will eventually come!