Xiao Chai Hu was revised in the manual, the adverse reactions were clear, and the market for varieties under Baiyun Mountain changed

Xiao Chaihu, who was once considered one of the "anti-viral panacea" for clearing fever, will revise the drug instructions.

A few days ago, the reporter of the Compliance and Development Research Group of Nandu Pharmaceutical Enterprise noted from the State Food and Drug Administration that the bureau has requested the revision of the instructions for the small chai hu preparation drug (6 dosage forms). In this revision, the adverse reactions and contraindications of this variety have been clarified, and the precautions have also been adjusted.

According to the Nandu reporter, before the revision of the instruction manual, the adverse reactions and contraindications of Xiao Chai Hu were marked as "not yet clear". According to the data monitoring of the State Food and Drug Administration, Xiao Chai Hu can see nausea, vomiting, bloating, abdominal pain, abdominal discomfort, diarrhea, rash, itching, flushing, sweating, dizziness, drowsiness, chest discomfort, allergic reactions, palpitations and other adverse reactions. It is forbidden for those who are allergic to this variety and the ingredients contained therein. In terms of precautions, it is particularly important to pay attention to the fact that it should not be used by those who have signs of wind and cold, and those with allergies should use it with caution.

Previously, on the instructions for small chai hu preparations, adverse reactions and contraindications were marked as "not yet clear"

The State Food and Drug Administration requires that the holder of the marketing authorization for Xiaochaihu granules submit a supplementary application for the revision of the instructions in accordance with the requirements of the revision of the instructions, and report to the provincial drug supervision and administration department for the record before March 5 next year.

Nandu reporter noted that at present, there are 114 drug approvals for Xiaochaihu preparations nationwide, including Baiyun Mountain (00874), Tongrentang, China Resources Sanjiu and other listed companies.

As a commonly used proprietary Chinese medicine for detoxification and treatment of colds, the current Xiao chai hu preparation is mainly based on OTC (over-the-counter) preparations. According to data from the Intranet, in the Chinese urban retail pharmacy terminal cold proprietary Chinese medicine market in 2020, the market retail sales of Xiaochai hu granules fell from 667 million yuan in 2019 to 633 million yuan in 2020.

Nandu reporter noted that Baiyunshan Guanghua Pharmaceutical's small chai hu granules are an important brand in this category, but under the overall shrinkage of the market of this variety, the sales of the company's products in the retail terminal have shrunk from 331 million yuan in 2019 to 310 million yuan in 2020. According to Baiyun Mountain's 2020 financial report, the sales of Xiaochaihu Granules last year were 296 million yuan, and last year's sales volume fell by 3.99% compared with 2019.

The industry believes that in the current situation of the decline in the income of the Baiyun Mountain Da Nan Pharmaceutical Plate, after the heavy variety Xiao Chai Hu was revised in the instructions, its drug population was also limited, and the drug market may change.

Nandu reporter Babe