These major achievements will change your life and mine

Today, the release of the major results of the 2024 Zhongguancun Forum Annual Conference was held. The relevant persons in charge of nearly 20 major achievements such as the Huairou Comprehensive National Science Center have made a series of international advanced achievements, the Suzaku No. 2 liquid oxygen methane launch vehicle, the ultra-large-scale integrated optical quantum chip, and the new generation of atomic magnetometer magnetoencephalography and other nearly 20 major achievements shared their insights and messages.

At the event, the results of reports such as "Deep Time Digital Earth International Big Science Program - Earth Science Research Trends (2014-2023)" and "2023 Technology Focus" were also released. The signing ceremony of the important landing achievements of the Zhongguancun Forum was also held at the scene. The Municipal Science and Technology Commission and the Zhongguancun Management Committee signed strategic cooperation agreements with foreign-funded enterprises and international science and technology parks, and Haidian District signed an agreement with the first batch of enterprises settled in Beijing Zhongguancun Comprehensive Bonded Zone.

01

Facing the world's frontier of science and technology

Major scientific and technological achievements 1: Huairou Comprehensive National Science Center has achieved a series of international advanced achievements

Issued by: Peking University, Institute of High Energy Physics, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Institute of Physics, Chinese Academy of Sciences, Institute of Theoretical Physics, Chinese Academy of Sciences, Institute of Atmospheric Physics, Chinese Academy of Sciences

Huairou Comprehensive National Science Center, which is the core support for Beijing's construction of an international science and technology innovation center, has entered the stage of paying equal attention to construction and operation, and a number of internationally advanced original achievements have emerged. The high-energy synchrotron radiation light source that is accelerating the construction is one of the fourth generation of the world's brightest fourth-generation synchrotron radiation light source, and its two-stage accelerator, the booster, has been completed and successfully emitted, and it is getting closer and closer to emitting the "brightest light". The National Center for Biomedical Imaging Science of Peking University has successfully developed a space station two-photon microscope, which is the first time in the world to analyze the structure and metabolic components of astronauts' skin cells during space flight, providing an important technical means for the future use of China's space station platform to carry out aerospace medicine and brain science research. How to achieve extremely low temperature refrigeration without helium is an important topic in the scientific community. The team of the Institute of Physics of the Chinese Academy of Sciences has discovered the spin supersolid state in actual materials for the first time by relying on the comprehensive extreme conditions experimental device, which can be used as a new principle of ultra-low temperature magnetic refrigeration working fluid with superior performance, and provide a new solution for solving the problem of extremely low temperature refrigeration in the field of human deep space exploration. The Institute of Atmospheric Physics of the Chinese Academy of Sciences released the Earth System Model CAS-ESM2.0, which can invert the Earth's past, observe the Earth's present, and predict the Earth's future through numerical simulation, providing a basis for decision-making on disaster prevention and mitigation and responding to global challenges such as climate change. The source of independent innovation, more than upward, chasing the light.

Major scientific and technological achievement 2: Let the laser pace be the same - phase synchronization reconfigurable Mohr nanolaser

Issued by: Peking University

Nanoscale lasers are the core devices of future optoelectronic integrated chips, which are crucial to the development of information science and technology with low energy consumption and high computing power. For the first time, the research team of Peking University proposed a Moiré nanolaser combining moiré fringe and nanolaser technology, which realized the coherent and reconfigurable function of nanolasers and opened up a path for exploring smaller, smarter and more powerful laser light sources.

Major scientific and technological achievements three: deep integration of storage and computing - intelligent chip with integrated storage and computing

Issued by: Tsinghua University, China Mobile Research Institute

The computing power required for AI models doubles every 100 days, and the rapid development of artificial intelligence has brought huge computing power demand, and traditional data computing is far from meeting the growing demand for higher intelligence levels. The world's first full-system integrated storage and computing chip developed by the Tsinghua team that supports efficient on-chip learning has comprehensively broken through the bottleneck of energy efficiency under the traditional architecture, and in the case of artificial intelligence computing, the simplified system architecture not only helps improve operational efficiency, but also greatly reduces power consumption. In the new era of digital civilization of the Internet of Everything, it provides a new path for the development of high-computing power chips.

Major scientific and technological achievement 4: rewriting the gene code - a new protein clustering method realizes the innovation of base editing technology

Issued by: Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing Qihe Biotechnology Co., Ltd

Base editing is considered the next generation of gene editing technology, which is more precise than other existing gene editing technologies and can edit specific base pairs on DNA or RNA. The research team of the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences pioneered the artificial intelligence-assisted structure-based protein clustering method, broke through the problem of stuck points with limited sources of enzymes for base editing tools, and developed the base editor CyDENT, which will have a positive and extensive impact on the fields of agricultural breeding and precision medicine.

Major scientific and technological achievement 5: Exploring the mystery of development - embryonic stem cell chimeric monkey

Published by: Center for Excellence in Brain Science and Intelligent Technology, Chinese Academy of Sciences

Voiceover text: Chimerism experiments are the gold standard for assessing the developmental potential of embryonic stem cells. For the first time, the research team of the Center for Excellence in Brain Intelligence of the Chinese Academy of Sciences has successfully constructed a high proportion of embryonic stem cell-derived birth survival chimeric monkeys, proving that primate embryonic stem cells can efficiently generate chimeras, which is at the international leading level in the field of primate stem cells, and this work has also laid a technical foundation for the construction of genetically modified model monkeys.

02

Facing the main battlefield of the economy

Major scientific and technological achievement 1: the green messenger of space exploration - Suzaku 2 liquid oxygen methane launch vehicle

Issued by: Blue Arrow Space Technology Co., Ltd

In July 2023, Suzaku 2 took off from the Jiuquan Satellite Launch Center, and it is the world's first liquid oxygen methane rocket to successfully enter orbit. The Blue Arrow aerospace team has made breakthroughs in a number of key technologies and developed the world's first Suzaku No. 2 liquid oxygen methane launch vehicle that has been successfully launched into orbit continuously and stably, representing that the mainland has fully mastered the key technologies of liquid oxygen methane launch vehicles and started a new journey in the development of domestic reusable liquid oxygen methane launch vehicles.

Major scientific and technological achievements 2: 10,000 meters have reached the future deeper - 12,000 meters of ultra-deep well automatic drilling rig

Issued by: China National Petroleum Corporation

On March 4, 2024, the 12,000-meter ultra-deep well automated drilling rig helped PetroChina's 10,000-meter "Gemini" exploration well, one of the 10,000-meter "Gemini" exploration wells, to drill 10,000 meters underground, setting a record for the deepest well in Asia.

This achievement has realized the world's first 10,000-meter well drilling rig automatic operation, fully localized equipment, green operation, and digital operation and maintenance, which is a major weapon for deep oil and gas development and deep scientific exploration.

Major Scientific and Technological Achievements 3: Unleashing the Value of Data - Chang'an Chain Privacy Computing Open Platform

Issued by: Beijing Microchip Blockchain and Edge Computing Research Institute

At present, data has become a key production factor driving the development of the global digital economy, but the safe circulation and rational use of data face many challenges such as privacy protection and trusted exchange. Chang'an Chain pioneered the combination of blockchain and privacy computing to create a trusted privacy computing solution, which can provide a strong guarantee for the circulation of highly sensitive and high-value data in multiple fields such as finance and government affairs, help the safe, credible and orderly flow of data elements, release the value of data, and accelerate the formation of new momentum for the digital economy.

Major scientific and technological achievement 4: accelerate the "coal to oil" - a new generation of iron-based Fischer-Tropsch synthetic catalysts

Issued by: China Energy Group, Beijing Institute of Low Carbon and Clean Energy

In the process of "coal to oil", the importance of catalysts is comparable to that of chips in the electronics industry, which can greatly affect the efficiency of "coal to oil". The "new generation of iron-based Fischer-Tropsch synthesis catalysts" has increased the oil yield by about 20% compared with the previous generation of catalysts, and in terms of carbon reduction, it can reduce carbon dioxide emissions by 150,000 tons for every 1 million tons of fuel oil produced. This achievement has further enhanced the technical capability of coal-to-liquids and ensured national energy security.

Major scientific and technological achievements five: all-weather "physical examination" for the power grid - basic industrial software for the analysis of new power systems

Issued by: State Grid Corporation of China

The mainland ranks first in the world in terms of power grid scale, new energy grid-connected capacity and development speed. In view of the world-class scientific problem of all-weather "physical examination" of ultra-large power systems, the State Grid Corporation of China has developed a new basic industrial software for power system analysis, which for the first time has improved the analysis scale of large-scale power systems from milliseconds to microseconds, and the scanning accuracy has been increased by 1,000 times. It provides system-level key technical support for the transmission of ultra-high voltage transmission and large-scale new energy and hydropower bases in the mainland, and realizes the creation and leadership of China's basic software for the power industry.

03

Facing the major needs of the country

Major scientific and technological achievement 1: to build the core of a quantum computer - a super-large-scale integrated optical quantum chip

Published by: Peking University, Institute of Microelectronics, Chinese Academy of Sciences, Zhejiang University

Optical quantum chips are one of the important technology platforms for the practical application of quantum computing and quantum communication. The world's largest integrated optical quantum chip (subtitle: 2500 optical quantum devices) developed by a scientific research team composed of Peking University, Institute of Microelectronics, Chinese Academy of Sciences, Zhejiang University, etc., realizes the quantum computing function based on graph theory and expands the application scenarios of optical quantum chips.

Major scientific and technological achievements 2: the "vanguard" of electromagnetic detection - Reedberg atomic electromagnetic detection system

Issued by: Beijing Institute of Quantum Information Science

The Rydberg Atomic Electromagnetic Detection System, also known as the Atomic Antenna, uses a highly excited atom to achieve a spectral detection range and higher sensitivity than traditional metal antennas. The achievement is a highly integrated atomic antenna system, which realizes wireless high-definition video signal reception, verifies multi-frequency interference-free communication, and the electromagnetic detection range and sensitivity have reached the international leading level, and has been initially applied in electromagnetic measurement, lightning detection, atomic radar and other fields.

Major Scientific and Technological Achievements III: Intelligent Empowerment of All Things, Linking the Future - 6G Synaesthesia Computing Technology Platform and Modern Semantic Communication System

Issued by: China Mobile Communications Group Co., Ltd., Zhongguancun Fanlian Mobile Communication Technology Innovation and Application Research Institute

China Mobile, Beijing University of Posts and Telecommunications and TD Industry Alliance jointly initiated the establishment of Zhongguancun Fanlian Mobile Communication Technology Innovation and Application Research Institute, to create a cloud-native open 6G synaesthesia computing intelligence integration test and verification platform, providing a basic foundation for the mainland's 6G cross-domain integration research, successfully incubating the world's first 6G cloud-based end-to-end semantic communication system, realizing a three-fold increase in information transmission efficiency, which is expected to greatly reduce the cost of information circulation in the whole society, and has broad application prospects in various fields in the future.

Major Scientific and Technological Achievement 4: New Contribution to Food Security: Creating a New High-yield Semi-Dwarf Wheat Based on Plant Hormone Balance

Issued by: China Agricultural University

Through 10 years of large-scale field phenotypic investigation and genetic research, the research team of China Agricultural University has identified a key gene locus that significantly improves the yield of wheat populations, which provides important genetic resources and new breeding strategies for the cultivation of new varieties of high-yield and high-efficiency semi-dwarf wheat, which has increased wheat yield by more than 10% and provided strong scientific and technological support for the world's food abundance.

04

Facing people's lives and health

Major scientific and technological achievement 1: deciphering brain images - a new generation of atomic magnetometer magnetoencephalography

Issued by: Peking University

The magnetoencephalograph developed by the scientific research team of Peking University using atomic magnetometer technology has successfully broken through the key core technologies such as miniaturization, high bandwidth, multi-axis detection of weak magnetic sensing and open magnetic shielding, greatly enhanced the ability to capture magnetic encephalography signals, and realized the world's first wireless magnetic encephalogram detection, providing new and powerful tools for the diagnosis of major brain diseases and brain science research.

Major Scientific and Technological Achievement 2: A New Tool for Decoding the Book of Life - Stereo-seq, a Spatiotemporal Omics Technology

Issued by: BGI Institute of Life Sciences

The spatiotemporal omics technology independently developed by BGI is an in-situ panoramic spatial omics technology, which can study the localization and function of cells and molecules in tissues from the dimensions of time and space, and improves the resolution of understanding life space to the subcellular level of 500 nanometers, with a field of view of up to 13 cm x 13 cm. As an underlying tool for human beings to re-understand organ structure, life development, species evolution and disease definition, more than 300 top scientists from 37 countries and regions have spontaneously formed the International Spatiotemporal Omics Alliance, using this tool to jointly decode the "Book of Life".

Major scientific and technological achievement 3: the key to deciphering the brain code - a universal neuropeptide fluorescent probe toolkit

Issued by: Peking University

Neuropeptides are special information substances in the brain, which control the complex signal network of the brain and are active substances that synergistically regulate the function of the nervous system. The "Universal Neuropeptide Fluorescent Probe Toolkit" developed by Peking University can dynamically monitor the changes of neuropeptide concentration in cells, tissues and animals with high spatiotemporal resolution, which provides an important tool for studying the release, regulation and function of neuropeptides in physiological and pathological states, and provides important platform technical support for brain science research.

Major scientific and technological achievements 4: the key "chip" of biomanufacturing - synthetic biomanufacturing chassis strains

Issued by: Tsinghua University, Beijing Yanwei Technology Co., Ltd

Chassis cells are the key "chips" of biomanufacturing, and they are the core technology common platform for the efficient and low-carbon synthesis of chemicals and materials. The team of Tsinghua University and Beijing Yanwei Technology Co., Ltd. took the lead in elucidating the mechanism of high stress resistance of Rhodococcus in the world, and successfully developed high-stress resistance and high-expression Rhodococcus chassis cells, providing a new biosynthesis scheme for high-value chemicals in the fields of food, medicine, daily chemicals, and energy.

Major Scientific and Technological Achievements V: Protecting Life and Guarding Health - Innovative Drugs and Devices Have Achieved a Series of Achievements

1. Protect life and health - innovative drugs and devices have achieved a series of results

Novel ALPK1 small molecule agonist

Issued by: Beijing Municipal Science and Technology Commission, Zhongguancun Science and Technology Park Management Committee, Beijing Yanming Biotechnology Co., Ltd

2. Protect life and health - innovative drugs and devices have achieved a series of results

Elbergostim α injection

Issued by: Beijing Municipal Science and Technology Commission, Zhongguancun Science and Technology Park Management Committee, Yiyi Biopharmaceutical (Beijing) Co., Ltd

3. Protect life and health - innovative drugs and devices have achieved a series of results

Chromosomal aneuploidy and gene microdeletion detection kit (reversible end-stop sequencing method)

Issued by: Beijing Municipal Science and Technology Commission, Zhongguancun Science and Technology Park Management Committee, Annoroad Gene Technology (Beijing) Co., Ltd

The team of academician Shao Feng of the Beijing Institute of Biological Sciences was the first in the world to discover the ALPK1 target, and on this basis, Yanming Biosciences has developed the world's first targeted drug to solve the problem of low response rate of tumor immunotherapy, and is expected to bring a new treatment option to cancer patients. The elbergostim α injection developed by Yiyi Biotech is the first innovative biological drug approved for marketing in China, the United States and Europe in China, and has become the preferred drug recommended by the American Society of Clinical Oncology guidelines for the prevention and treatment of neutropenia after chemotherapy in cancer patients. The first prenatal "chromosomal aneuploidy and gene microdeletion" detection kit based on next-generation sequencing methodology developed by Annoroad has positive significance for the prevention and treatment of birth defects by detecting chromosomal variations in amniotic fluid samples.

Source丨Beijing News