According to the latest analysis by fan group ProtonDB, Valve's Steam Deck now natively supports 80% of Steam's top 100 games.

PCGamesN noted that the community tested the game against Valve's Proton compatibility layer, and only 10% of the top 100 games in the Steam Store were completely incompatible, and the rest of the games achieved varying degrees of success.
While games like Destiny 2 and New World are not yet compatible, it's unclear if this is a developer limitation or some other reason.
In an interview with PC Gamer, designer Lawrence Yang said that the Portal game works well on the Steam platform, but WDV 2 still needs to be further improved. He confirmed: "I think we do need to check all the Valve catalogs to make sure it works well on steam Deck. ”
In addition, designer Greg Coomer also said that the Dota team is doing something very innovative, at least in the context of Dota.