Glycine is an important amino acid that is widely used in pesticides, chemicals, medical, pharmaceuticals, feed and other fields. In China, glycine was produced in the 1980s. Most of them rely on chlor-alkali plant construction, with chloroacetic acid as the main raw material. Production is limited. With the advent of glyphosate herbicides, the use of glycine in the pesticide industry has increased rapidly.
In recent years, China's glycine industry has developed rapidly, from an annual output of 70,000 tons to an annual output of 410,000 tons in just over ten years. In recent years, driven by glyphosate, China's glycine industry has achieved rapid development, continuous expansion of production capacity, and increasing output, resulting in oversupply of glycine, overcapacity in the glycine industry, and the industry operating rate is at a low level, about 50%. With the improvement and improvement of environmental protection requirements, the operating rate of glycine projects began to decline. In recent years, the situation of overcapacity in the glycine industry has been eliminated, due to limited supply, demand continues to be strong, the domestic glycine production capacity reached 410,000 tons, the output of 331,000 tons. (Source: Champs Consulting)

At present, 80% of glycine in China is used to produce glyphosate. Glycine is an important intermediate in the synthesis of glyphosate. Glyphosate is one of the most widely used pesticides in the world, with a high proportion and strong weed control activity. Due to the rapid expansion of the global planting area of genetically modified crops, many of the world's commodity crops have glyphosate-resistant genes, stimulating and stimulating the production and consumption of glyphosate. In the long run, the demand for glycine is still gradually increasing.
There are many methods of glycine production, including direct fermentation, enzymatic method (using microbial cells or enzymes produced by microorganisms to make glycine), extraction method (protein hydrolysis, extracted from hydrolysate) and so on. The traditional extraction method, enzymatic method and chemical synthesis method are difficult to achieve the purpose of industrial production due to the high cost of precursors and complex processes. With the construction of vector and receptor systems and the improvement of in vitro gene recombination technology, the construction of glycine bioengine bioengine bacteria has been further developed.
Membrane separation technology is a new type of separation technology that can show many advantages in applications. Compared with the traditional separation operation, it has the characteristics of low energy consumption, high separation effect, no secondary pollution, simple process, long service life, low comprehensive cost of equipment and high cost performance. Reverse osmosis membrane modules play an important role in water treatment, biopharmaceuticals, separation and concentration in the food industry and other fields.
Reverse osmosis membrane modules use primary film forming technology to increase the thickness of the film layer and obtain greater value at a lower cost. The application of reverse osmosis membrane modules in glycine production, the product purity is high, the safety is high. Compared with other separation methods, reverse osmosis membrane modules are carried out at room temperature without phase transitions, chemical reactions, decomposition and denaturation of products. At the same time, it has the effect of desalting, ash reduction and improving purity. The use of a variety of reverse osmosis membrane modules to separate glycine under different operating conditions can effectively solve the problems existing in the traditional process and help glycine enter the "golden age".