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Cold knowledge science popularization | why should I prepare for pregnancy for three months?

I believe that many people know that it takes three months to prepare for pregnancy, but why is it three months to prepare for pregnancy? Is there a scientific basis? Why not one month, two months, six months? Today, Xiaobian will provide you with the scientific principle behind the "three months of pregnancy".

Usually we think that the signs of the beginning of pregnancy are to quit smoking and alcohol, adjust a healthy lifestyle, and most importantly, both men and women, especially women, to start supplementing with folic acid.

The scientific basis for "three months of pregnancy" is derived from the need to supplement folic acid for three months to make the level of red blood cell folate in the body reach the threshold of preventing neural tube malformations.

Cold knowledge science popularization | why should I prepare for pregnancy for three months?

Why should folic acid be supplemented for three months?

Folic acid, which has an irreplaceable position for cell synthesis and proliferation in vivo, mainly through the participation of 5-methyltetrahydrofolate in the synthesis of body core acid and nucleotide, further complete the manufacture of DNA and RNA. That is to say, folic acid plays a key role in sperm and egg quality, especially for the proliferation and division of early fertilized eggs, embryonic development after successful conception, and differentiation and development of fetal organs.

Therefore, folic acid is the "basic nutrient" to ensure the growth and development of embryonic cells. Folic acid needs to be supplemented for three months to meet the needs of embryonic cell growth and development, mainly because the supplementation of synthetic folic acid for three months to make the level of red blood cell folate in the body reach the threshold of preventing neural tube malformations, while red blood cell folic acid is dominated by 5-methyltetrahydrofolate.

However, Chinese due to genetic factors, many people (78.4%) even if they supplement for three months, the level of 5-methyltetrahydrofolate in the body can not reach the ideal state, and even in the process of supplementing the synthesis of folic acid, unmetabolized folic acid is produced, causing potential toxic side effects to the human body.

Cold knowledge science popularization | why should I prepare for pregnancy for three months?
Cold knowledge science popularization | why should I prepare for pregnancy for three months?

Both natural and synthetic folic acid from food need to be metabolized to 5-methyltetrahydrofolate (5-MTHF) and absorbed. Medical vitamin active folic acid (5-methyltetrahydrofolate) does not need to be metabolized, can be directly absorbed by the human body, and people with folic acid metabolism disorders can also be directly absorbed. Quickly increase the level of 5-methyltetrahydrofolate in the body to better protect the health of mothers and babies.

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