Can dhea improve egg quality? Can I eat dhea when pregnant?

Can dhea improve egg quality? Can I eat dhea when pregnant?

DHEA, also known as dehydroepiandrosterone, is a weak androgen drug that facilitates ovulation induction and increases the probability of ovulation, and has a maintenance and helpful effect on patients with premature ovarian failure, and is often used in endocrinology. However, it is not recommended to take hormonal drugs for a long time, there may be other side effects, and it is necessary to observe the course of medication and whether it is effective, if it is effective, you can continue to take it, and on the contrary, stop long-term use. hu

Pregnant women do not need to eat DHEA, which is not good for health, pregnant women should supplement with calcium, folic acid, vitamins, lecithin and DHA, DHA is to help the baby's brain development.

Usually ovarian function may lead to premature ovarian failure, difficulty ovulating, or no ovulation for a variety of reasons. It is recommended that patients taking endocrine drugs need to be cautious, and at the same time try to use symptomatically, not drugs that have the effect of helping pregnancy can be used, and it is necessary to identify the specific causes of infertility and give appropriate drugs to avoid the situation where side effects are higher than the efficacy.

Many European countries still have considerable restrictions on DHEA, such as in Belgium, the Netherlands, the United Kingdom, Germany, etc., all of which have adopted bans. In 2010, Europe and the United States newly studied DHEAAMH, a derivative of DHEA, France proposed a more convincing research report, DHEAAMH was verified to supplement DHEA, and prevent the genetic variation produced by DHEA, but also has a significant effect on the quality of the ovaries, follicles, eggs and so on.

Since then, based on the safe way to solve the problems of endogenous and exogenous women affecting fertility, the American Endocrine Society, together with the American College of Obstetricians and Gynecologists, the American Society of Reproductive Medicine, the European Endocrinology Society and the International Menopause Society, has appointed a working group to re-evaluate the published factors affecting fertility and issue guidelines for the treatment of the compound pregnancy repair factor DHEA AMH. ANALYSIS OF DHEA AMH: DHEA balances the hormone levels of the preconception mother, and AMH increases the reserve function of the egg.

This is why everyone found that all the PREVIOUS DHEA in North America and Europe, North America, and Europe were removed from the shelves. DHEA AMH is a comprehensive replacement for DHEA.

In 2000, the European Union first proposed, in addition to drugs, to help women with healthy natural pregnancy and test tubes in plant extraction. Subsequently, the United States also proposed that it would work with the European Union to study how to assist in test tubes and natural fertilization. The American Endocrinology Society, together with organizations such as the American College of Obstetricians and Gynecologists, has appointed a working group to consider women's natural pregnancies and ivory tubes from multiple dimensions and systems

Problems with success and embryo quality have issued guidelines for the treatment of THE COMPOUND PREGNANCY REPAIR FACTOR DHEA AMH.

Compound pregnancy-ready repair factor DHEA AMH – a guideline for multisystem therapy

Natural Pregnancy IVF – How to Have a Healthy Environment for Egg and Embryo Implantation

Analysis of the significance of DHEA AMH: DHEA balances the hormone levels of the preconception mother, and AMH increases the reserve function of eggs.

Female conception is the physiological process by which sperm and egg meet and reach the uterus:

(1) First of all, the internal and external reproductive system is developed normally, to ensure the normal progress of sexual life, and the function of egg picking, egg delivery, fertilization and transporting fertilized eggs to the uterine cavity of the fallopian tube is good.

(2) Female endocrine axis hypothalamic-pituitary-ovarian function is normal, mature follicles are discharged, forming corpus luteum and functioning well.

(3) Cyclical changes in the proliferation period and secretion period of the endometrium Conducive to implantation of fertilized eggs, any abnormality in the above links can lead to fertility disorders.

Ovarian reserve function refers to the ability of the ovarian cortex to form fertilized oocytes, determined primarily by the number of sinus follicles within the ovaries and their quality. People try various options for declining ovarian function, but do not achieve the desired results. In 2000, the European Union and others reported for the first time that DHEA AMH was used for a group of unexplained elderly women who could not have children, and the level of blood insulin-like growth factor in patients after the first application of DHEA AMH was increased, which improved the recruitment and development of follicles, and then the role of DHEA AMH in the field of reproduction was studied for several consecutive years, and it was believed that DHEA AMH can mainly improve the ovarian environment, repair the ovaries, provide nutrition for the ovaries, and improve the number of fertilized oocytes and embryos. And it can improve the quality of oocytes and embryos, improve pregnancy rates, reduce chromosomal aneuploidy, and reduce miscarriage rates.

The prevalence of aneuploidy in embryos produced through test tubes from 27 consecutive IVF women who also underwent a preimplantation genetic diagnosis (PGD) was assessed. Of these cycles, 19 entered the IVF without DHEAAMH treatment and 8 received DHEAAMH supplementation at least 4 weeks before the IVF started.

DHEAAMH treatment can result in a higher oocyte count increasing from about 8.5 to about 10.4. In this case, there was no significant difference between the absolute number of post-DHEAAMH integer ampploidy embryos and the percentage of integer diploid embryos, but between untreated and treated patients. As a woman ages, the percentage of integers produced by the embryo decreases dramatically. Therefore, the increase in oploid outcomes in older women is significant evidence of the effectiveness of DHEAAMH in improving embryo quality, and DHEAAMH pretreatment on women with egg failure may significantly increase their chances of transferring at least one integerploid embryo. (Can dhea improve egg quality?) Can I eat dhea when pregnant? ）

Precautions for medication during pregnancy:

Pregnancy is a special period in which the mother and fetus are two closely related independent individuals in the same environment, and their physiological response and sensitivity to drugs vary greatly. Because many organs of the fetus are not yet functional, they mainly rely on the placenta rather than their own organs to obtain essential nutrients and excrete metabolites. When the drug appears in the mother's blood, due to this dependence of the fetus on the mother, it is bound to affect the growth and development of the fetus.

The first 3 months of pregnancy is the development period of embryonic tissue, limbs and organ systems are forming, and are particularly sensitive to some teratogenic drugs. Therefore, in the first trimester, we should try to avoid casual medication, especially drugs that have not been fully studied. At 4 to 9 months of gestation, the fetal development has matured at this stage, but many organ functions are still immature, there is no ability to metabolize and excrete drugs, and they are highly susceptible to drug damage, unless absolutely necessary.

Pregnancy often has to be treated with drugs due to some comorbidities, as long as the rational use of drugs can prevent the fetus from being affected by maternal diseases. If pregnant women with severe tuberculosis have been observed, treatment with isoniazid, streptomycin, and sodium paraamosalicylate can reduce the incidence of neonatal malnutrition by half compared with the control group, and stillbirths are also reduced; pregnant women with iron deficiency anemia or diabetes mellitus are treated with iron preparations or insulin, respectively, to reduce fetal and neonatal mortality.

Another benefit of DHEAAMH is that pregnancy rates in women are unexpectedly high, especially in women with weakened ovarian function. DHEAAMH supplementation has also been linked to increased cumulative pregnancy rates and shortened pregnancy intervals, with evidence of decreased ovarian function into the evaluation and treatment of inability to conceive.

During the 10-year period from 2005 to 2015, a case-control study was conducted on 190 women over the age of 30 with weakened ovarian function. The study group included 89 patients with an average age of about 41.6 years who supplemented with about 75 mg of oral micronized DHEA per day for up to four months before entering IVF. The control group consisted of 101 patients with an average age of approximately 40.0 years who were treated for inability to conceive but did not use DHEAAMH. The main result is a clinical pregnancy after the patient's initial presentation.

Ovarian stimulation was the same in the study and control groups, including micro-dose agonist stimulation followed by the maximum dose of gonadotropin stimulation, using about 300-450 IU of FSH and about 150 IU of HMG. Study patients continued to receive DHEAAMH until a positive pregnancy test was obtained or until the patient stopped treatment.

Using the risk model developed, the proportional risk of pregnancy in women using DHEAAMH was compared with the control group. As a result, the cumulative clinical pregnancy rate in the study group was significantly higher (28% of 89 patients with 25 pregnancies and 11% of 101 patients with 11 pregnancies; specifically, about 58% of patients receiving DHEAAMH achieved clinical pregnancy, and about 11% of patients who did not receive DHEAAMH achieved clinical pregnancy. Thus, DHEAAMH treatment increases the percentage of clinical pregnancies by about 130% to about 180%.

As the clinical pregnancy rate increased, the miscarriage rate decreased after the average age of about 31.6 years in this study received DHEAAMH treatment. Clinical data provide evidence that DHEAAMH supplementation improves natural pregnancy rates, IVF pregnancy rates, cumulative pregnancy rates, and shortens pregnancy intervals.

Pregnant women's diet is a college question! What to eat? What shouldn't I eat? What is good for the fetus to eat? What do you eat that affect fetal health? If these questions make your head so big! Check out these 14 questions and answers about diet during pregnancy.

Question 1: Does drinking a cold drink or eating ice cause contractions?

A: When you drink a cold drink and feel that your stomach is strange, it is not because of cold drinks or ice products that cause contractions, but because the food temperature is low, and eating into the stomach causes gastrointestinal discomfort. Studies have shown that when a pregnant woman's hand touches the ice, the blood vessels of the uterus will contract, and the blood circulation relative to the fetus will be poor, affecting its growth. Therefore, pregnant women should eat less ice cream, popsicles and other foods, as for cold drinks, as long as they are placed at room temperature, the temperature exceeds 10 ° C or more.

Question 2: Can I eat spicy?

A: Eating chili peppers has no effect on pregnant women and babies. Pepper contains a substance that numbs the nerves, which will affect the baby's nerves, so pregnant mothers must pay attention to not eating to make the mouth tingle when eating peppers, and eat in moderation. When eating chili peppers, as long as you grasp the principle of whether the mouth feels numb, pregnant women can eat spicy with peace of mind.

Question 3: Can I eat hot and dry foods such as durian and ginger?

A: Will make the body blood sugar rise, once the mother's blood sugar increases, the baby will be easy to be too heavy, so if pregnant women want to eat durian, to each meal is not more than the size of an orange, that is, about half a piece of durian can be, so as not to eat too much, resulting in too large fetus. Ginger is a hot and dry food, but it is also a natural ingredient to improve the vomiting symptoms of pregnant women, so put some ginger when cooking, about a thumb-sized portion, can alleviate morning sickness, but do not take too much!

Question 4: Is it easy to miscarry after eating papaya and aloe vera?

A: Papaya contains female hormones, which is easy to interfere with the hormonal changes in the body of pregnant women, especially green papaya, pregnant women should be completely abstained, because it is not only harmful to the stability of the fetus, but also may lead to miscarriage. In Southeast Asian countries, local residents will also eat papaya for contraception, which shows that papaya is not conducive to production. As for aloe vera, there have been experiments on animals, and studies have found that aloe vera will cause miscarriage results in animals, so pregnant mothers are still better off eating less.

Question 5: Can't drink or smoke?

A: Smoking in the first trimester of pregnancy may increase the chances of a rabbit lip or cleft jaw in the fetus. If you smoke during pregnancy or often inhale second-hand smoke, your baby is more likely to have learning disabilities or behavioral problems in the future.

The third trimester of pregnancy is the stage of communication and connection between fetal nerve cells and the brain, many nerve conductive substances will be affected by alcohol, which will cause serious damage to the brain development of the fetus, and women with alcohol addiction should quit alcohol before pregnancy.

Question 6: Can I drink the soup when pregnant?

Answer: Decoction medicinal warm supplement is mainly to let women through menstruation and alleviate discomfort symptoms. According to Chinese medicine, the fire is greater during pregnancy, and drinking the soup at this time may have doubts about the fire. Some women have the habit of taking the soup before pregnancy, sometimes in the early stages of pregnancy because they do not know that they are pregnant still take, according to the Taiwan Tsumura Shuntian company, taking the soup during pregnancy, there is no adverse effect on the fetus, but there will be a phenomenon of physical change after pregnancy, so after confirming pregnancy, it is recommended to stop drinking the soup.

Question 7: Can I eat Chuanbei loquat cream for coughing?

A: The formula of Chuanbei loquat cream varies, some of which contain "safflower" which are contraceptive herbs belonging to traditional Chinese medicine, and special attention must be paid when purchasing. In fact, any discomfort during pregnancy should be discussed with the doctor before treatment, so cough can not eat Chuanbei loquat cream, as long as the drug formula is determined, after discussing with the doctor, you can naturally take it with peace of mind. In addition, the treatment of cough is not only to eat Chuanbei loquat cream, after seeing a doctor, there will naturally be a more suitable treatment for pregnancy.

Question 8: Can pregnant women eat pink ginseng or ginseng?

A: On the bed, Chinese medicine generally recommends using ginseng in the case of "qi deficiency", which can replenish qi and have a fetal effect. For some pregnant women with real heat constitution, or pregnant women with a hot constitution in the third trimester of pregnancy, if they take ginseng warm supplements, it is possible to help the fire and move the fetus and aggravate the discomfort of pregnancy. There are many types of ginseng, such as Korean ginseng, Jilin ginseng, dang ginseng, pink ginseng, prince ginseng, etc., there are differences in warm supplements, flat supplements or cool supplements, so it is the best way to take them after discussing with a doctor.

Question 9: Will a baby eat papaya get jaundice?

A: Jaundice is mainly due to elevated bilirubin in the blood, resulting in yellowing of the sclera (the white part of the eye) and skin. The average person's excessive intake of red and yellow vegetables and fruits, such as carrots, melons, papayas, oranges, willows, persimmons, mangoes, etc., will make the carotene content in the blood too high, carotene deposited in the skin, will make the skin yellow. However, at present, there are no clinical reports of jaundice in newborns caused by pregnant women or pregnant women due to the consumption of papaya, and the consumption of papaya is not related to the occurrence of jaundice.

Question 10: Eat bird's nest, can the baby avoid jaundice?

A: There is no basis for this statement in TCM. Bird's nest, sweet and flat, nourishing yin and dryness, tonifying the qi, clinically generally used in the after-illness physical weakness conditioning. Bird's nest is regarded as a treasure, and I am afraid that it will fall into the trap of "rare things are precious". Due to the differences in customs and customs of various parts of the Chinese nation, some areas will encourage pregnant women to eat more bird's nest to supplement their bodies, but clinically it is still necessary to pay special attention to the fact that bird's nest contains animal protein, and pregnant women with specific constitutions should be careful to eat bird's nest and cause allergic reactions.

Question 11: Can you raise a fetus by eating more huanglian, ginseng, and medicinal liquor?

A: Bitter taste, cold sex. It has the function of clearing heat, dryness and dampness, diarrhea and detoxification, but if it is taken or taken for too long, it is easy to defeat the stomach. However, Chinese medicine believes that there are evidences and the use of drugs, such as some pregnancy obstruction (i.e., pregnancy vomiting), is caused by stomach fever, and clinically it will also use huanglian to treat.

If you blindly think that the pregnancy is weak, blindly enter a sweet and hot supplement such as ginseng, it is like pouring oil on the fire, which is bound to make the internal heat rise suddenly, and the blood fever is arbitrary, which can lead to threatened miscarriage, or prolong the labor process and lead to obstructed labor. Medicinal liquor contains alcohol ingredients, which have a great impact on the fetus, and expectant mothers must not be afraid.

Question 12: Will eating coix seeds drop the fetus?

Answer: Ren is a familiar and often eaten food and traditional Chinese medicine, its taste is light, slightly cold, has a healthy spleen and stomach, water leakage, heat and pus removal. However, the root of coix kernels was used in ancient books for abortion. In addition, experimental studies have also found that coix seed oil will increase the euphoric contraction of the uterus of rabbits and guinea pigs. The Qing Dynasty's book "Seeking Truth in Materia Medica" also mentions that there are pregnant women, and it is not appropriate to use them in vain, and to leak out with sex.

Question 13: Can pregnant women take ready medicine?

A: Single-flavored Chinese herbal medicines with toxic side effects often appear in proprietary Chinese medicines in the form of formulas, so you should be cautious when taking them. The main chinese proprietary Chinese medicines that should be contraindicated are bovine yolk detoxification pills, bovine yolk qingxin pills, rheumatic medicines, bruise medicines, etc., and even the use of wound medicine patches should be cautious and should not be used for too long. Clinically, as long as the doctor is correct in the dialectic and the medication is appropriate, even if the drug is poisonous and taboo, it can also make the disease go to the fetal safety. Therefore, once pregnant women are sick, they can still use more controversial drugs, but when their condition improves, they are considered to stop and are no longer used.

Question 14: Can pregnant women not drink coffee or tea?

A: Tea and other beverages contain caffeine, expectant mothers should reduce the amount of coffee or tea they drink in the first 3 months of pregnancy, it is best not to drink. Some related studies have pointed out that drinking too much coffee can increase the chance of fetal malformations, miscarriage, and low birth weight. At the same time, the excitatory effect of caffeine is also easy to cause fetal arrhythmia, pregnant women's heart beat faster, increase urination, invisibly increasing the burden of the heart and kidneys, so pregnant women still think twice! (Can dhea improve egg quality?) Can I eat dhea when pregnant? ）

DHEAAMH adjuvant therapy can significantly improve the ovarian responsiveness of people with poor ovarian function, thereby improving their ovarian reserve function, and ultimately improving the outcome of IVF, increasing the number and quality of eggs retrieved by women, increasing the number of embryos, improving the quality, increasing the natural pregnancy rate, increasing the in vitro fertilization (IVF) pregnancy rate, accumulating pregnancy rate and time of conception, reducing the abortion rate, at least partially reducing the aneuploidy rate.

A comparison of ovarian reserve function and clinically relevant parameters for the IVF cycle before and after the use of DHEAAMH is shown in Table 1.

A comparison of parameters related to IVF before and after DHEAAMH use is shown in Table 2.

DHEAAMH uses pre- and post-FET cycle pregnancy outcome-related parameters compared again, again IVF fertility assistance. See Table 3.

DHEAAMH can reduce the rate of embryonic aneuploidy, and the comparative analysis of the embryonic integrity of patients with low ovarian function performed and the non-DHEAAMH pretreatment patients found that the embryo integrity rate of patients with DHEAAMH pretreatment reached 100%, compared with only 53% in the control group. It was found that DHEAAMH pretreatment significantly reduced the number and proportion of chromosome aneuploidy in embryos. The aneuploidy rate of human embryonic chromosomes increases with age, and the interaction between various signals during follicle generation leads to the failure of plate collection in the oocyte chromosome and increases the risk of chromosomes not being separated from aneuploidy.

After conceiving the baby, every family hopes that pregnant women can smoothly and smoothly pass the pregnancy, expectant mothers will have uncertain factors during pregnancy, which is easy to cause miscarriage, Xiaobian helps you take stock of these pregnancy precautions, and hopes that every mother can safely spend the pregnancy. (Can dhea improve egg quality?) Can I eat dhea when pregnant? ）