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Studies involving 300,000 people have shown that people with excessive blood sugar have a high risk of cancer

To tell you a sad news:

Recently, a 18-year study of more than 300,000 diabetics published in the top medical journal "The Lancet - Diabetes and Endocrinology" showed that heart disease and stroke are no longer the main causes of death in diabetics, and cancer is posing a greater threat to the lives of diabetics.

Don't think this news is only related to diabetics, the 2020 diabetes survey results show that about 400 million people on the mainland are in prediabetes (blood sugar is above the standard but below the diabetes standard).

How does high blood sugar get into trouble with cancer cells? What is the difference between pre-diabetes and diabetes? "Life Times" (search for "LT0385" in WeChat can be followed) interviewed experts to sort out the high-risk groups of cancer caused by various factors, and what to do in daily life to effectively prevent cancer.

Experts interviewed

Chen Xiaoyan, Director of the Department of Endocrinology, The First Affiliated Hospital of Guangzhou Medical University,

Liu Juntian, Director of the Cancer Prevention Medical Center of Tianjin Medical University Cancer Hospital

You Changxuan, chief physician of the Department of Oncology, Southern Hospital of Southern Medical University

4 reasons why cancer is eyeing sugar friends

The incidence of almost all cancers in diabetic patients will be higher than in the general population, especially digestive tract tumors, such as liver, gallbladder, pancreas, intestines, etc.

Previous studies have found that the risk of diabetes-related cancer peaks about 8 years after diabetes is diagnosed.

Tumor growth is a slow process, from cancer cells to cancerous tissue, cancerous mass usually takes a long time, and the high blood sugar environment in diabetic patients may lead to accelerated tumor progression, usually in 5 to 10 years, and 8 years is just a median.

The large preglycemic population is more worrisome than diabetes:

Prediabetes refers to high blood glucose but not meeting the diagnostic criteria for diabetes mellitus, fasting blood glucose 6.1 to 7 mmol/L, or oral glucose tolerance 7.8 to 11.1 mmol/L. Pre-diabetes are mostly asymptomatic and are usually accidentally discovered during a physical examination.

The high risk and rapid progression of cancer caused by a high glycemic environment may have the following reasons.

High insulin

Stimulates tumor growth

Obese type 2 diabetics usually have higher levels of insulin, and insulin has a similar effect to growth factors, and long-term high levels can easily become a breeding ground for tumors.

hyperglycemia

Cancer cells multiply out of control

If the blood glucose control is not good, the human body is in a high blood sugar environment for a long time, many functional proteins will be glycosylated, so that it loses its original physiological function, such as removing foreign bodies and garbage in the body, "monitoring" the emergence of tumors, etc. The ability to "monitor" the occurrence of tumors will decline, so it is easy to make cancer cells multiply "out of control".

In a high blood sugar environment, diabetics may also face the problem of infection that is difficult to heal. If the chronic infection is repeated, chronic enteritis, hepatitis, gastritis, etc., may become a high risk factor for cancer.

Excessive avoidance

Decreased resistance

In order to control blood sugar, some sugar friends adopt the strategy of "inappropriate restriction of diet", resulting in unbalanced nutrition and decreased resistance.

Diabetics need to control their diet, but it does not mean that they cannot eat anything, but they need to carry out scientific diet management, can not be partial to food, and need to maintain nutritional balance.

Down in the dumps

Affects autoimmunity

The occurrence of cancer is also related to emotions. Many sugar friends think of long-term control of diet, and fight against diabetes, it is inevitable that they will be depressed, which will affect their own immune function.

How exactly is cancer screening done?

The latest data released by the National Cancer Center in February 2022 shows that the top 6 malignant tumors in the mainland are lung cancer, colorectal cancer, stomach cancer, liver cancer and esophageal cancer, breast cancer, and Life Jun sorted out high-risk groups and taught everyone to initially choose screening programs.

1

lung cancer

High-risk groups: people over 50 years of age, with a history of smoking, a family history of lung cancer, old lung lesions (such as tuberculosis), living in an air pollution environment, and long-term exposure to radiation and chemical products.

Main screening methods: ordinary X-ray examination, low-dose CT of the lungs, tumor marker examination, etc.

2

breast cancer

High-risk groups: women over 35 years of age, with a family history of breast cancer, breast disease history, breast cancer pathogenic genetic mutations, menarche age less than 12 years old, menopausal age greater than 55 years old, childless or first childbearing age greater than 35 years old, long-term use of contraceptives or estrogen substitutes and other groups.

Main screening methods: breast palpation, breast ultrasound, mammography, etc.

3

Colorectal cancer

High-risk groups: people over 50 years old, with a family history of colorectal cancer, chronic colitis and intestinal polyps, and a long-term high-fat, high-protein, low-fiber diet.

Main screening methods: examination, fecal occult blood examination, colonoscopy, tumor marker examination, etc.

4

gastric cancer

High-risk groups: people over 40 years old, with a family history of stomach cancer, Helicobacter pylori infection, chronic stomach disease, like to eat pickled and smoked food, smoke and alcohol, stress, and irregular life.

Main screening methods: gastroscopy, Helicobacter pylori examination, pepsinogen detection, etc.

5

hepatocarcinoma

High-risk groups: long-term heavy alcohol consumption, chronic hepatitis B or cirrhosis patients, long-term exposure to chemical agents.

Main screening methods: ultrasonography, liver enhancement CT, tumor marker examination, etc.

6

Esophageal carcinoma

High-risk groups: over 40 years old, have a family history of esophageal cancer or come from areas with a high incidence of esophageal cancer, have upper gastrointestinal symptoms, have precancerous diseases or precancerous lesions of the esophagus, smoke and alcohol abuse and other people.

Main screening methods: barium x-ray examination, esophagoscopy, esophageal function measurement, etc.

It should be reminded that cancer screening is highly professional, and it is necessary to choose a qualified institution.

10 tips to help you stay away from cancer

The American Cancer Society released the "Next 10 Years Of Tumor First-level Fight Plan" in 2018, and the 10 major anti-cancer strategies given are worthy of reference, and sugar friends are also applicable.

Stay away from 11 pathogens

Eleven pathogens, including Helicobacter pylori, hepatitis B virus, hepatitis C virus, human papillomavirus (HPV), Epstein-Barr virus, HIV (HIV), Thai liver flux, Chinese mycodystis (hepatosomiasis), and Schistosomiasis Egypt, increase cancer risk.

It is recommended to get vaccinated in time and have a timely physical examination when you are unwell.

Sun protection

Sun exposure is the biggest risk factor for skin cancer, and sun protection is the most effective way to reduce the risk of skin cancer.

Reduce unnecessary medical radiation

The American Cancer Society considers all ionizing radiation to be carcinogenic. Going to a professional institution to find a professional doctor can not only ensure the screening effect but also reduce unnecessary medical radiation.

Reduce indoor pollution

Radon pollution, formaldehyde pollution, benzene pollution, etc. will all have an impact on physical health. Before renovating a new home, you can ask a professional testing agency to conduct an indoor environment test, and decide whether you can move in according to the test results.

More ventilation in the home can reduce the concentration of radon, formaldehyde and other indoors.

Quit smoking

Tobacco control is a top priority in cancer prevention. Cancer mortality in the United States has fallen by 26 percent since 1991, more than half of which is attributed to declining smoking rates.

Quitting smoking is good for people of any age.

Teetotal

Excessive alcohol consumption can cause many adverse effects on the body, even a small amount of alcohol will increase the risk of some cancers, in order to prevent cancer is best to drink alcohol.

7

Control weight

More than 20 different types of cancer have been linked to obesity, the most notably rectal, endometrial and esophageal adenocarcinomas.

8

Healthy eating

Reducing red meat intake and restricting consumption of processed meat may reduce cancer risk. Eat a balanced diet and eat fruits, vegetables, whole grains, proteins, and dairy products every day.

9

Keep exercising

People who do at least 30 to 60 minutes of high-intensity physical exercise every day have a reduced risk of cancer, especially breast, colon, prostate, lung and endometrial cancers.

Adults are recommended to do at least 150 minutes of moderate-intensity aerobic exercise or 75 minutes of high-intensity exercise per week; or a combination of the two exercises in equal amounts.

10

Regular screening

In addition to cancer screening, it is also necessary to do regular hepatitis virus screening and HIV screening.

In addition, long-term work pressure, anxiety, irregular life also affects health, usually to combine work and leisure, learn to adjust the mood, relieve stress. ▲

Editor: Jie Zhang

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