More than a month ago, a 1-year-old baby died unexpectedly, and after grief, the parents decided to donate a pair of the baby's kidneys, one of which was successfully matched with nono (pseudonym), a 4-year-old child with uremia.
On January 30, the surging news (www.thepaper.cn) reporter learned from Renji Hospital affiliated to Shanghai Jiaotong University Medical College that the urological kidney transplant team of the hospital has successfully performed kidney transplant surgery for Nono, which is the youngest age of kidney transplantation for patients with uremia since the hospital carried out kidney transplant surgery. After the operation, nono creatinine quickly returned to normal, eliminated the pain of peritoneal dialysis, and has been successfully discharged from the hospital.
It is worth mentioning that on the occasion of the Lunar New Year, the kidney transplant team of Renji Hospital specially sent a New Year gift package to Nono, wishing her a speedy recovery. The hospital said that after another six months of stability, Nono can go to school like other children.
The kidney transplant team of Renji Hospital specially sent a Chinese New Year gift package to Nono. The pictures in this article are provided by Shanghai Renji Hospital
Due to a cold visit, he was unexpectedly diagnosed with uremia
According to Nono's family, as early as April 2021, Nono was found to have renal insufficiency when he was admitted to the hospital for a cold, and then blood creatinine quickly rose to 500 mmol/L (normal serum creatinine range is 44-133 mmol/L), and in just 2 months, it progressed to kidney failure, commonly known as uremia.
Nono's parents are difficult to accept this fact, but genetic testing clearly found that Nono has INVS gene variation, which is related to autosomal recessive genetic disease infantile renal unit nephrodiasis type 2, combined with clinical manifestations, it can be basically determined that the primary disease causing nono uremia is infantile renal unit nephrotic tuberculosis type 2.
Zhang Ming, chief physician of the Department of Urology of Renji Hospital, introduced that the kidney unit kidney tuberculosis suffered by Nono is a group of rare autosomal recessive inherited cystic kidney diseases, and 20 pathogenic genes have been identified, but there is no effective treatment and intervention. "For children with this type of uremia, dialysis treatment is often less effective, and kidney transplantation can maintain the lives of children for a long time."
Since then, Nono's condition has progressed rapidly, and he was once admitted to the intensive care unit due to the deterioration of his condition, and began to receive temporary hemodialysis treatment, and after his condition stabilized, he changed to peritoneal dialysis to continue maintenance treatment. Every time he was treated, Nono didn't cry or make a fuss and was very cooperative. The parents did not want the child to spend her childhood in non-stop dialysis, so they took her to the kidney transplant clinic of Renji Hospital, and under the guidance of Dr. Li Dawei, a series of examinations and tests were perfected, and Nono finally successfully completed the registration on the national kidney transplant registration system, and then waited for the appropriate kidney source.
Kidney transplant surgery.
Eventually wait until the right kidney source
The waiting process is long, 4 times a day peritoneal dialysis can only barely maintain life, Nono's body is getting weaker and weaker, and even drinking water has become a luxury. Because the kidneys of uremia patients cannot expel excess water from the body, drinking more water is easy to induce serious complications such as heart failure.
"We can only let her drink drop by drop, and most of the time we don't dare to let her drink at all." Nono's parents said that until more than a month ago, the child was successfully matched with the kidneys of a 1-year-old who died in an accident.
After matching the appropriate kidney source, the kidney transplant team of Renji Hospital immediately prepared, discussed and assessed the surgical risks, and formulated a precise and perfect surgical and treatment plan. In early December 2021, Nono was taken to the operating room. The whole operation went well and she has been discharged from the hospital.
Zhang Ming told the surging news reporter that in recent years, the incidence of uremia in children has increased, and common causes include various primary glomerulonephritis, congenital, hereditary or cystic kidney diseases, etc. Due to the limited means of diagnosis and treatment before, many children cannot get a clear diagnosis, or are abandoned without treatment. According to statistics, nearly 95% of children with kidney transplantation can survive to adulthood, and child kidney transplantation has become the best choice to save the lives of children with uremia.