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Minimally invasive surgery solved the problem of mitral regurgitation, and the hospital successfully completed transcatheter mitral valve clamping

Text/Yangcheng Evening News all-media reporter Zhang Hua

Correspondents Zhang Yang, Huang Rui, Mai Yiting

Without opening the chest, only the catheter intervention is needed to repair the mitral valve of the patient's heart, and the problem of severe prolapse and reflux of the mitral valve is solved. On December 30, the Department of Cardiology of Sun Yat-sen Memorial Hospital of Sun Yat-sen University successfully performed transcatheter mitral valve clamping for two patients. It is reported that this is the first time that Guangdong Province has independently completed transcatheter mitral valve clamping, and it is also the first time that the hospital has successfully carried out minimally invasive mitral valve repair after the hospital successfully carried out dragonfly national multi-center clinical research in July 2021, marking another major breakthrough in the field of structural heart disease diagnosis and treatment in the province.

Minimally invasive surgery solved the problem of mitral regurgitation, and the hospital successfully completed transcatheter mitral valve clamping

Professor Chen Banxin and Professor Zhou Shuxian performed transcatheter mitral valve clamping for patients

Cardiovascular disease diagnosis and treatment is widely used in high-precision technology

Recently, high-precision surgery has been widely used in the diagnosis and treatment of cardiovascular diseases in Guangdong Province. Professor Wang Jingfeng, chairman-designate of the Electrophysiology and Pacing Branch of the Chinese Medical Association, chairman of the Cardiovascular Disease Branch of the Guangdong Medical Association, and director of the Department of Cardiovascular Medicine of Sun Yat-sen Memorial Hospital of Sun Yat-sen University, said in an interview with reporters, "Due to changes in lifestyle, the incidence and mortality of cardiovascular diseases in the country are very high, and Guangdong is no exception. In order to improve the diagnosis and treatment level of cardiovascular diseases, our hospital boldly adopts advanced technologies at home and abroad, including the application of innovative drugs and medical devices. With these 'weapons', patients have obvious efficacy, increased safety, and significantly reduced side effects. ”

According to the reporter's understanding, since the 1970s, Sun Yat-sen Memorial Hospital of Sun Yat-sen University has taken the lead in carrying out one-stop multidisciplinary collaboration (MDT) diagnosis and treatment of complex cardiovascular diseases nationwide, and in 2021, it will implement multidisciplinary consultation for 236 patients to solve difficult problems. At present, the cardiovascular medicine team will continue to work in the cardiovascular field, especially in the field of structural heart disease, including minimally invasive aortic valve replacement, mitral valve repair/replacement, congenital heart disease blockade, left atrial appendage blockage, etc., to further improve the level of diagnosis and treatment, so that more patients can enjoy a new life. Professor Wang Jingfeng also revealed that in order to further improve the level of cardiovascular diagnosis and treatment, the hospital will also integrate resources and build a platform to establish a cardiovascular disease hospital as soon as possible.

Wang Jingfeng introduced that since 2014, mitral valve clamping has been carried out in the United States in 1152 cases, and then it has increased year by year, reaching 10460 cases in 2019. Global multicenter studies have shown that the total adverse events after mitral valve clamping are 55% and 73% compared with traditional surgery, which has obvious advantages, and the probability of postoperative regurgitation above moderate to severe is comparable to that of surgery. More importantly, it is significantly better than surgery in terms of safety.

As of August 2021, 65 cases of mitral valve clamping had been performed in 15 hospitals in 11 provinces across the country. Sun Yat-sen Memorial Hospital of Sun Yat-sen University is the first unit in Guangdong Province to independently complete mitral valve clamping.

Minimally invasive surgery solved the problem of mitral regurgitation, and the hospital successfully completed transcatheter mitral valve clamping

The team performing mitral valve clamping at Sun Yat-sen Memorial Hospital of Sun Yat-sen University

Interventional therapy may be an option for high-risk patients

According to reports, the two patients who underwent mitral valve clamping were Ms. Li, 64, and Mr. Chen, 51, whose preoperative cardiac ultrasound showed mitral valve prolapse and severe reflux with heart failure.

"Sometimes it's hard for me to sleep lying flat, because I have trouble breathing when I lie down, so I can only sleep sitting." It turned out that Ms. Li had an acute heart failure attack, had been rescued in the local hospital in Zhongshan, and coughed up pink foamy phlegm when her condition was serious. Her heart problems have caused her quality of life to plummet.

Another patient, Mr. Chen, was diagnosed with acute left heart failure, which was a difficult lesion in the near-junction area of the A3/P3 area. A month earlier, he had begun to feel visibly breathless, breathless, and he himself was terrified of surgery. "For wounds of more than ten centimeters of open chest, it takes two to three weeks to be hospitalized. I just can't take it. ”

After a thorough case analysis and discussion of these two patients before surgery, combined with the strong wishes of the patients, the expert team decided to perform minimally invasive mitral valve clamping surgery for them. Professor Chen Banxin, vice president of the hospital and professor of cardiovascular medicine, told reporters: "Mitral valve reflux is a disease that is aging and the most common heart valve disease. According to statistics, about 10% of the elderly over 75 years old have mitral regurgitation, which seriously affects the quality of life and safety of patients. ”

For the application of high-tech technology, Professor Chen Said, this is a blessing for patients. "In the past, the most effective means of mitral regurgitation treatment was cardiac surgery mitral valve repair or prosthetic valve replacement, but the surgery itself is traumatic and has certain risks. Therefore, for some patients with high risk factors such as advanced age, poor cardiac function, and comorbidities, they lose the opportunity for treatment due to the high risk of surgery, and some patients lose the optimal treatment time or lead to death because they are particularly resistant to surgery and delay the appropriate treatment of the final disease progression. ”

Minimally invasive surgery solved the problem of mitral regurgitation, and the hospital successfully completed transcatheter mitral valve clamping

Ms. Li presented a pennant to the medical team before discharge

It is expected that domestic cardiovascular innovative devices can lead the industry

"Compared with traditional treatment methods, mitral valve clamping is less invasive, safer, no extracorporeal circulation is required during surgery, and we basically do not need to prepare blood. The patient recovered quickly after the operation, ms. Li got out of bed one day after the operation, and was discharged from the hospital in two or three days. Professor Chen said.

Good surgical results are possible thanks to the advanced technology and instruments used by the experts. Director Wang Jingfeng said that in July 2021, the hospital successfully carried out a national multi-center clinical study of the domestic Dragonfly system for mitral valve clamping, and it is expected that there will be clinical research results after the end of 2022. At present, the products of more than a dozen pharmaceutical companies in China are undergoing clinical research on mitral valve clamping.

It is understood that in 2020, the domestic medical device market size of 800 billion yuan, about one-third of the drug, but the industry maintains a high-speed growth trend, the annual market growth rate of 20% of the device market is about 4 times the growth rate of the global medical device and domestic drug market. "The listing of domestic drugs or devices will greatly reduce the treatment cost of mitral regurgitation, and will also promote the development of industries related to minimally invasive treatment of heart disease." Chen Fanxin said, "I hope that domestic pharmaceutical companies will be the leaders of the industry under the impetus of innovative thinking to develop towards import substitution and internationalization." (For more news, please pay attention to Yangcheng Pie pai.ycwb.com)

Source | Yangcheng Evening News Yangcheng Pie

Image | Hospital provided

Editor-in-charge | Chen Liang

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