This is the 3767th article of Da Medical Care
Let me tell you a story: My good neighbor Aunt Wang accidentally broke a bone in March this year. The fracture is not unusual, the strange thing is that she just pulled the doorknob, with that "inch strength", coincidentally, the wrist was fractured... Hearing about Aunt Wang, I believe you must be very surprised: although women of the age are prone to osteoporosis, but like Aunt Wang so easily fractured, this bone has to be "loose" to what extent...
In fact, Aunt Wang's fractures are so strange, and the osteoporosis is so serious, there are all inducements. In addition to being a congenital factor of "middle-aged and elderly women after menopause", the more important reason is that Aunt Wang is a patient who has removed thyroid nodules and has been taking drugs that regulate thyroid function for a long time. So, in other words, it is certain drugs that people take for a long time that exacerbate osteoporosis. Maybe in your family's small medicine box, there are these common medicines that aggravate bone pine. Today, we will take a look at it and avoid the risk of osteoporosis for you from the perspective of medication.
1. 【Thyroxine medicine】
Currently, more and more people are suffering from thyroid diseases, especially thyroid nodules/even thyroid cancer. These people are often accompanied by decreased thyroxine secretion after surgery, so it is necessary to take thyroxine drugs for supplemental treatment. Common thyroxine drugs include Euthyrothema/Raitis.
In general, in order to prevent the recurrence of thyroid tumors, clinically a slightly larger dose of thyroxine drugs is often given to supplement thyroxine and keep the thyroid state "excited". But in the long run, excess thyroxine will cause the destruction of bone cells greater than the regeneration of bone cells, that is, our bones are in a state of "insufficient income" for a long time, and osteoporosis is easy to occur.
Therefore, if you are a thyroid dysfunctional person, even if osteoporosis has not occurred at present, but has entered the middle and elderly stage, then it is best to take some preventive measures under the guidance of a doctor as soon as possible.
2. 【Glucocorticoid drugs】
Glucocorticoid drugs are also widely used because of their important role in anti-allergic/anti-infective/anti-shock/treatment of autoimmune diseases. For example, patients with asthma/henoch-schönlein purpura/meningitis/toxic pneumonia/cardiogenic shock/rheumatism/lupus erythematosus/nephrotic syndrome will be treated with glucocorticoid drugs for long-term treatment.
However, long-term use of such drugs will cause a decrease in osteoblasts, that is, the trabecular bone in the bone will continue to decrease, which will lead to osteoporosis and even necrosis of the femoral head. Such drugs mainly include hydrocortisone / prednisone / dexamethasone / betamethasone and the like. If glucocorticoids are used for more than one year, the incidence of osteoporosis can be as high as 30% to 50%.
Therefore, if you have chronic low back pain/joint pain/limited activity in the process of using glucocorticoid drugs, you must ask a professional doctor to intervene as soon as possible to determine whether drug-induced osteoporosis has occurred, and start taking drugs to prevent osteoporosis as soon as possible, such as calcium/vitamin D.
In fact, in the common clinical osteoporosis, 9%-17% are caused by drugs, so drug-induced osteoporosis is not uncommon, but it is easy to be ignored by us.
Of course, the drugs that control the course of the disease must also be taken on time, and cannot be wasted because of choking. It's just that from today onwards, you're planning for the risk of osteoporosis that you might have. Fortunately, the family doctor is close by your side, and if necessary, you can seek guidance and help from your contracted family doctor.
Author: Shanghai Changning District Xinjing Town Community Health Service Center
Zhou Xiangjun Deputy Chief Physician