Recently, the increase in acute hepatitis cases of unknown origin among children has attracted global attention. According to the WHO website, as of 21 April, at least 169 cases of acute hepatitis of unknown origin have been reported in many countries, and adenovirus has been detected in at least 74 cases. In the UK alone, 114 children are sick, 10 of whom require liver transplants. Infected people are usually healthy, young children.
In response to the previous "European Surveillance" article pointed out that "the cause of the disease is adenovirus infection, may also be related to the new crown pandemic", who issued a bulletin saying that adenovirus is currently considered a hypothesis of etiology, but this can not be fully used to explain the severity of clinical symptoms. Other influencing factors, such as decreased levels of adenovirus transmission during the COVID-19 pandemic, increased susceptibility in young children, the possibility of a new adenovirus, and simultaneous infection with SARS-CoV-2, also require further investigation.
In addition, since the vast majority of affected children are not vaccinated against COVID-19, the hypothesis regarding the side effects of covid-19 vaccines is not currently supported. WHO is closely monitoring the situation and working with relevant parties such as UK health authorities.
United Kingdom: associated with adenovirus infection
On the 25th local time, the British Health Security Agency said that more and more evidence shows that a common virus is related to rare cases of hepatitis that have occurred in some young children recently. The UK's Health Security Agency said an adenovirus called F41 appeared to be the most likely cause of the disease.
Mila Chand, director of the UK's Clinical and Infectious Diseases Specialty, said information gathered through surveys by relevant departments increasingly suggested that the increase in sudden hepatitis in children was linked to adenovirus infection.
The first suspected case of acute hepatitis of unknown cause in Japan is suspected
Japan's Ministry of Health, Labor and Welfare issued a news on the 25th that the first case of children in Japan who may have this acute hepatitis has also appeared.
The confirmed case is a child under the age of 16, but no specific age, sex, residence, etc. were announced. Currently, the patient has sought medical attention. According to the Japan Broadcasting Association (NHK), unlike most previous cases in Europe and the United States, the patient was not detected with adenovirus.
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