If your poop suddenly changes
For example, it has changed from 1 time in 3 days to 3 times a day
When I go to work,
Couldn't resist rushing to the toilet again and again
Sometimes diarrhea
One operation is as fierce as a tiger
Sometimes constipation
Occupying the pit is not pulling out
After the end
It's always felt like it's not over
Always want to go to the toilet and squat a little longer
My stomach hurt faintly
The point is!
Take a closer look
Quite possibly
Your large intestine
I am suffering unbearable pain
The Large Intestine family has 5 brothers:
Cecum, appendix, colon, rectum and canal
There are more and more diseases related to the large intestine in China
Chronic inflammation of the intestine, colorectal cancer (colon cancer, rectal cancer), etc
Incidence is on the rise
Let's talk about it today
A good big bowel
Why is it so fragile...
Bubble tea, instant noodles
Hot pot, rice, large plates of chicken
These delicacies...
The large intestine cannot be eaten
Food that we swallowed
It passes through the esophagus, stomach, and small intestine
Digestion/Absorption Pipeline operation
When to the large intestine
The delicacy has turned into dregs
The large intestine is the "garbage disposal station" that deals with these slags.
Useful part recycling
The useless part is discharged
When the Garbage Bin is working properly
We don't feel it's there
But once the feeling happens
It was really sick
Sick to go?
...... It's too hard!
It may even be possible to survive with a lifelong illness!
Ulcerative colitis
Colorectal cancer
Are 2 common colorectal diseases[1]
Shinzo Abe's 50 Years of Disease Conflict
In the end, it "failed"!
This brings us to the table
How terrible is ulcerative colitis...
Ulcerative colitis is a chronic, lifelong disease
"Chronic" and "Lifelong"
The two words actually gave the patient a life sentence
Once sick
You have to accept that you will never be
"Carefree and healthy person" (living with illness)
It is often necessary to ask a question that strikes the soul:
"Did you take your medicine today?"
The disease is more common in young adults aged 20 to 40 years
Shinzo Abe developed ulcerative colitis at the age of 17
After illness
According to the study statistics[2]:
90% of patients experience it
The process of recurrence-remission-recurrence
There is no one-size-fits-all treatment
Complete control of symptoms for life
People who suffer from ulcerative colitis "life imprisonment"
What are you going through?
When ulcerative colitis recurs
Diarrhea, abdominal pain
Mucus pus bloody stool
Severe cases may go to the toilet a dozen times a day
30% of patients have other organ diseases[2]
Why does ulcerative colitis occur?
Still don't know[3]
At the moment
Ulcerative colitis is an autoimmune disease[3]
Immunization army "turned face and did not recognize people"
It is supposed to kill the enemy when it appears
Now it's brave... Shell yourself
For us, the immune army is still very mysterious
The cause is unclear
There is no cure for ulcerative colitis[3]
Medicine also has to accept reality in desperation
The goal of treatment is not a cure
Mainly to control symptoms
Prevents the appearance of serious complications
It's like in a mythological story
Crush the monsters that cannot be destroyed in the hell and the deep sea
Disease monsters will still break through the barrier from time to time
Intrusion into our lives
Most patients can be controlled with medications
But 15% still need surgery[3]
- Removal of the colon and/or rectum
Postoperative effects may affect patient bowel movements[4]
Paid
It is likely that it will no longer be an easy and happy thing
The scariest thing is
Ulcerative colitis is a recurrent, difficult chronic inflammation
It can lead to recurrent cell proliferation
Greatly increases the risk of cancer
Patients with a course of illness greater than 20 years
The risk of developing colorectal cancer is 10 to 15 times higher than that of normal people[5]
God is cruel
A person who falls into a disease
It is easier to fall into another, more terrible disease
Colon cancer
It's a dangerous character
Colon and rectal cancers are often summarized as colorectal cancers
(Also known as colorectal cancer)
The incidence of colorectal cancer in China is getting higher and higher
It often appears on the list of "tumor hot search lists"
Colorectal cancer may initially begin
Small, abnormally hyperplastic polyp tissue inside the colon[10]
These polyps may be small
There may be no symptoms
Most polyps are benign lesions
Not life-threatening
There are a subset of cells
Mutations are constantly occurring
Evolve into cancer cells that can grow wildly
Just like other cancers
Early colorectal cancer usually has no symptoms
No medical examinations are done
We couldn't find it at all
Symptoms are often detected
It is often in the middle and late stages
Once diagnosed with advanced colorectal cancer
Most may no longer have a chance of surgical cure[11]
The overall 5-year survival rate of colorectal cancer is different from country to country
Approximately 40%~78%[12-14]
However, there is no need to smell cancer discoloration[11]
There are many ways to treat colorectal cancer
Surgery, chemotherapy, targeted therapy, immunotherapy, etc
New treatments
Give the average overall survival time of advanced patients
It has been doubled, about 3 years
There is a saying in the field of oncology
All tumors are premeditated
Take bowel cancer, for example
From the production of intestinal polyps to the development of malignant tumors
It takes an average of 10 years[15]
In this way, the tumor slowly brewed and accumulated strength
Until it has the tenacious survival ability of malignant tumor cells
Until the spark of the stars becomes finally on fire
Many unhealthy lifestyles can facilitate this process
Many active and healthy lifestyles can slow down this process
Why are colorectal-related diseases getting higher and higher?
There are many influencing factors
An unhealthy lifestyle requires the biggest bite of the pot!
Some people have big fish and big meat
BBQ, fondue, cake and coke
Some people stay up late every day
A sitting is a day
Lack of exercise
Decreased gastrointestinal motility
Some people are constantly nervous
These are all risk factors for related diseases
Take colorectal cancer, for example
All of these factors can affect your risk of cancer[11]
Quit smoking, eat healthy, exercise regularly, etc
Active lifestyle
Can prevent the development of colorectal cancer[11]
Intestinal polyps and early colorectal cancer
Can only be detected through screening
High-risk groups should be screened for colonoscopy
It can be detected in tumor germination or early tumors
The earlier it is discovered
The better the treatment
If you experience these symptoms:
Bowel habits change suddenly
For example, stool has changed from 3 times a day to 3 times a day
It may also change from 1 poop per day to 3 times a day
Blood in the stool
Decreased appetite
Weight loss
……
May be a precursor to large bowel lesions[11]
These are not necessarily all cancers
However, it is a phenomenon that needs to be vigilant
You don't have a healthy lifestyle
Perhaps the prelude to colorectal disease
Special Author: Jiang Yongyuan | Master of Internal Medicine, Third Military Medical University
Review expert: Zhang Jianwei | Doctor of Medicine and Master Supervisor of Department of Internal Oncology, Sixth Affiliated Hospital of Sun Yat-sen University
bibliography
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https://medlineplus.gov/colonicdiseases.html
[2] Ford AC, Moayyedi P, Hanauer SB. Ulcerative colitis. [J] BMJ. 2013;346:f432.
[3] Ungaro R, Mehandru S, Allen PB, et al. Ulcerative colitis. [J] Lancet. 2017; 389(10080):1756-1770.
[4] Luo Yang,Yu Minhao,Chen Jianjun,Qin Jun,Huang Yizhou,Zhong Ming. Clinical efficacy of laparoscopic and open total colorectal resection of the canal in the treatment of ulcerative colitis[J].Chinese Journal of Gastrointestinal Surgery,2018,17(09):929-934.
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[6] Bray F , Ferlay J , Soerjomataram I , et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J]. CA: A Cancer Journal for Clinicians, 2018, 68(6):394-424.
[7] Yin J, Bai Z, Zhang J, et al. Burden of colorectal cancer in China, 1990-2017: Findings from the Global Burden of Disease Study 2017. [J] Chin J Cancer Res. 2019;31(3):489-498.
[8] Mauri G, Sartore-Bianchi A, Russo AG, et al. Early-onset colorectal cancer in young individuals. [J] Mol Oncol. 2019;13(2):109-131.
[9] Weinberg BA, Marshall JL. Colon Cancer in Young Adults: Trends and Their Implications. [J] Curr Oncol Rep. 2019;21(1):3.
[10] What Is Colorectal Cancer?https://www.cdc.gov/cancer/colorectal/basic_info/index.htm
[11] Dekker E, Tanis PJ, Vleugels JLA, et al. Colorectal cancer. [J] Lancet. 2019; 394(10207):1467-1480.
[12] Govindarajan A, Rabeneck L, Yun L, et al. Population-based assessment of the outcomes in patients with postcolonoscopy colorectal cancers. Gut. [J] 2016;65(6):971-976.
[13] Erichsen R, Baron JA, Stoffel EM, et al. Characteristics and survival of interval and sporadic colorectal cancer patients: a nationwide population-based cohort study. [J] Am J Gastroenterol. 2013;108(8):1332-1340.
[14] Cha JM, Kim HS, Kwak MS, et al. Features of Postcolonoscopy Colorectal Cancer and Survival Times of Patients in Korea. [J] Clin Gastroenterol Hepatol. 2019;17(4):786-788.
[15] Levine JS, Ahnen DJ. Adenomatous polyps of the colon. N Engl J Med. 2006;355:2551
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