Before IVF treatment, doctors check the chromosomes of the parents-to-be. Some mother embryos are discontinued, and examination reveals that the villous chromosomes are abnormal. In this way, parents have great doubts about this, "Our husband and wife have chromosome examinations, there is no problem, why is there a problem with the chromosomes of the embryo?" ”
Chromosomes are our genetic material, the carrier of genes, and the somatic cells of normal people are 23 pairs of chromosomes, including 22 pairs of autosomal and 1 pair of sex chromosomes. Gametes are made of sperm and egg combination, half of its chromosomes come from the mother, half from the father, in the process of sperm or egg formation, chromosomes may appear to be abnormal division, simply put, that is, sperm or eggs carry not 23 chromosomes, when abnormal sperm and egg combination, the formed embryo will appear chromosomal abnormalities. In addition, chromosomal errors can also occur during the division of the fertilized egg.
The most important risk factor for the abnormalities of the embryo's chromosomes is advanced age. After the age of 35, women's ovarian reserve function will plummet, the number of follicles will decrease, the probability of egg cell aging and abnormalities will increase, and chromosomal aneuploidy will increase. Males over the age of 35, fertility also gradually declines, male aging will also affect the genetic changes of offspring, resulting in increased telomere length, genetic mutations and genetic changes in performance, these risks increase linearly with the age of the father.
Therefore, if the general conditions are suitable for women over 38 years old, we still recommend the third generation of IVF fertility, which can exclude unnecessary abortion caused by abnormal embryonic chromosomes and reduce the harm to the mother.