I believe many people are full of curiosity. Some want to have a healthy baby, some want to choose the sex of the fetus, give birth to boys, give birth to girls, give birth to dragon and phoenix fetus, twins, then there are these special requirements can consider Thai ivy, then go to Thailand to do the third generation of IVF process will be complicated?
Introduction to IVF 3rd Generation:
The third generation ivory infant technology is divided into two parts, PGD and PGS
PGD (preimplantation genetic diagnosis), the pre-transplant genetic diagnosis, is the third generation of "test tube babies". It is mainly used to check whether embryos carry genes that are genetically defective.
It is based on IVF technology, sperm eggs in vitro binding to form a fertilized egg, and after developing into an embryo, genetic testing is carried out before it is implanted in the uterus, so that IVF in vitro in vitro to avoid some genetic diseases. At present, preimplantation genetic diagnosis can diagnose some diseases caused by single gene defects, such as hemophilia, thalassemia and other diseases, which can be directly detected through such diagnosis.
PGS (Preimplantation Genetic Screening), that is, preimplantation genetic screening, refers to an early prenatal screening method that detects the number of chromosomes and structural abnormalities of early embryos before implantation, and analyzes whether embryos have genetic material abnormalities by detecting the structure and number of 23 pairs of chromosomes in embryos at one time. In this way, normal embryos are selected for implantation in the uterus in order to obtain a normal pregnancy, improve the clinical pregnancy rate of patients, and reduce multiple pregnancies.
These two techniques are methods that obtain the genetic material of the embryo for analysis, screen for diagnosis for abnormalities, and then screen for healthy and high-quality embryo transfers, thereby improving the chances of embryo implantation success and avoiding unhealthy baby births.
Specific process steps of the third generation of IVF:
1. Ovulation induction therapy
Since not every egg can be fertilized, not every fertilized egg can develop into a viable embryo, so multiple eggs must be obtained from the woman's body to ensure that there are embryos that can be transferred, which requires ovulation induction treatment for women.
2. Egg retrieval
Under the guidance of ultrasound B, the doctor applies a special egg retrieval needle to puncture the mature follicles through the vagina and aspirate the eggs. Egg retrieval is usually performed under intravenous anesthesia, so women do not feel the pain caused by the puncture process.
3. Diagnosis of in vitro fertilization and screening
Sperm retrieval: When a woman retrieves an egg, a male performs a sperm retrieval. After the semen undergoes a special washing process, the sperm eggs are placed in a special medium in order to combine naturally. This is called conventional fertilization. When the sperm egg is fertilized to form an embryo, the doctor will conduct diagnostic screening through technical means, that is, the third generation of IVF PGD/PGS to ensure the quality of the embryo and avoid the transfer of unhealthy and unsympathetic embryos.
4. Embryo transfer
A few days after fertilization, a very thin embryo transfer tube is applied, the best embryo is transferred into the mother's uterus through the cervix, and the number of embryos transferred is determined according to age, embryo quality and previous IVF outcomes, usually 2 to 3 embryos. In recent years, in order to reduce the rate of multiple pregnancies, some centers have opted for single embryo transfer, or up to 2 embryos.
Because the embryo transfer tube is very thin and the doctor moves gently, the patient usually does not have any pain.
5. Luteal support
Due to the use of GnRH agonists/antagonists and ovulation-stimulating drugs, as well as the loss of follicular granule cells due to egg retrieval, women often have luteal insufficiency during the egg retrieval cycle and require luteal supplementation/support with progesterone and/or chorionic gonadotropin. If you are not pregnant, stop progesterone and wait for menstruation. If pregnant, progesterone is continued, usually 3 weeks after ultrasound sees fetal heartbeat.
6. Determination of pregnancy
Serum hCG is measured 14 days after embryo transfer to determine pregnancy. Serum HCG is measured again 21 days after embryo transfer to understand how the embryo is developing. 30 days after embryo transfer, a vaginal ultrasound is performed to determine whether there is an intrauterine pregnancy or not, with fetal heartbeat.
Hengjian overseas tip: The third generation IVF process seems to be relatively simple, but the operation of the whole process is very rigorous, because errors in any one link may lead to the failure of the entire IVF treatment. Therefore, it is recommended that patients who want to do IVF fertility must understand the knowledge of IVF in advance before doing IVF, so that they can not only relieve the pressure in the heart, but also better cooperate with the doctor's treatment.