Some couples have been pregnant for a long time, or have not been able to successfully conceive, go to the hospital to check the results and find infertility; some women, because they missed the optimal age of fertility, the ovarian function declined, the difficulty of successful conception is very large; and some tumor patients because of the later treatment will damage the ovarian function, pregnancy seems to be their dream... Do they really have no chance of giving birth? In response to everyone's concerns, on the afternoon of March 29, Nandu Health Lecture Hall invited Zhao Xiaomiao, chief physician of the Department of Reproductive Medicine of Guangdong Provincial People's Hospital, to bring a live lecture "Preparing for three children, pregnant strategies for elderly women!" , got 14w+ of traffic.
Zhao Xiaomiao (left), chief physician of the Department of Reproductive Medicine of Guangdong Provincial People's Hospital, was interviewed by Sister Zeng, the host of the Nandu Health Lecture Hall
Do these few things well to greatly improve the success rate of conception
Now many people often lament that it is really difficult to conceive a child, especially for elderly women who are preparing for three children. Repeated pregnancy failures have made many women who are trying to conceive have "menstrual phobia", and they are anxious when they see their menstruation every month. So how to improve the success rate of conception and let everyone realize their dreams of childbearing? Director Zhao Xiaomiao suggested that couples who are trying to become pregnant should do the following things.
First, calculate the ovulation period. Women who are trying to become pregnant should understand their menstrual cycle, the so-called menstrual cycle refers to the time interval between the first day of the two menstrual periods, generally speaking, this cycle is 28 days, and it is normal to advance or postpone seven days later. And from the first day of the next menstruation back to 14 days is the day of ovulation, generally in the days before and after the ovulation day of intercourse is more likely to get pregnant, there are data show that the same room before the day of ovulation is better than the day after the ovulation day, because the survival time after the egg is generally 12-24 hours, some can be up to 48 hours; but the sperm can survive for 2-5 days after excretion, and some can be as long as 7 days. "You can also observe your own ovulation through the ovulation test strip, and if you see a faint red color on the test strip, you can have the same room every other day."
Second, if infertility is suspected, intervene as early as possible. "Generally speaking, if you don't get pregnant without contraception for a year, you're infertile." For infertility, Director Zhao said that it is necessary to intervene as soon as possible, especially for women over the age of 35, if they have not successfully conceived after half a year without contraception, they can go to the hospital for examination. Women themselves can also be judged by the menstrual cycle, and if the menstrual cycle is beyond the normal range, they should be vigilant for ovulation disorders. At the same time, diseases such as blocked fallopian tubes in women, pelvic inflammatory disease, and weak spermatozoa in men can lead to infertility, which requires further examination in the hospital.
Third, maintain healthy lifestyle habits. First of all, we must ensure a healthy work and rest, and cannot stay up late; secondly, we must pay attention to balanced diet, eat more high-quality protein, whole grains, and foods high in vitamins; supplement folic acid and multivitamins.
Fourth, pay attention to the frequency of intercourse. Generally speaking, the frequency of intercourse is more appropriate 2-3 times a week, and there is no need to wait until a few days before ovulation to have intercourse, and regular sperm evacuation exercises are also required at other times. At present, the normal morphology of male sperm is normal in 4%-5%, most of the sperm quality is relatively poor, and more sperm excretion helps to output high-quality sperm.
Director Zhao Xiaomiao is explaining the precautions for pregnancy preparation
Artificial insemination and IVF are suitable for these groups, respectively
Pregnancy is becoming increasingly difficult for some older women, at a time when artificial insemination and IVF open up new possibilities for them. Director Zhao Xiaomiao introduced in the live broadcast that the 40-year-old of women is generally used as a watershed for artificial insemination and IVF in clinical practice. Before the age of 40, women have at least one side of the fallopian tube is unobstructed, and the man's sperm quality is poor or the men and women are normal in various examinations, and infertility for unknown reasons can be artificially inseminated; women over the age of 40, ovarian function declines, the success rate of artificial insemination is very low, and IVF is a better choice.
At present, IVF is divided into three generations, and many people are wondering whether the higher the algebra means the higher the success rate. Director Zhao Xiaomiao gave the answer to this, this idea is wrong, the three-generation scheme is for different situations, the first generation is to take out the man's sperm and the woman's egg, let it combine freely; the second generation is for the man's poor sperm situation, artificially grasp the sperm, injected into the egg; the third generation is mainly for the family with genetic disease genes, the embryo in question is screened out, leaving the normal embryo transplanted back into the body. Therefore, choosing the right program for yourself can really improve the success rate of pregnancy.
Obesity can also lead to infertility
"Successful pregnancy requires these three elements: women can ovulate normally, men's sperm are active and dense, and women's vagina, cervix, uterus, fallopian tubes, and pelvic patency are indispensable." If they cannot get pregnant, Director Zhao Xiaomiao suggested that women can check the uterus and ovaries through ultrasound, evaluate ovarian function through AMH (anti-Mullerian hormone) and sex hormone testing, and men can have sperm motility tested. If there is no problem with the above tests, go to the salpingogram. Director Zhao said that the reason why this examination is placed at the end is also out of love for women, because this examination is a slight invasive examination and will cause discomfort to women.
Speaking of the factors that cause women to become difficult to conceive, Director Zhao said that ovarian function will indeed decrease with age, coupled with the serious environmental pollution and pressure of life, many young girls have also experienced premature ovarian failure, so it is necessary to conduct regular ovarian function examinations. "The AMH test is now very convenient and can be done with a blood test, with no time limit and fasting requirements." In addition, obesity is also an important factor that makes it difficult for women to conceive. "Not all fat girls have problems, but because some obesity is caused by other diseases, such as insulin resistance." Director Zhao Xiaomiao reminded that once obese women find their menstrual abnormalities, hairiness, and acne increase, they should be careful of polycystic ovary syndrome, which will affect pregnancy if not treated in time.
Fertility preservation to help tumor patients successfully conceive
In recent years, female fertility preservation has gradually entered our field of vision, female fertility preservation mainly refers to the preservation of women's eggs, ovarian tissue or embryos that have been formed, in the case of temporary non-fertility. At present, the main applicable population of domestic fertility preservation is female tumor and blood disease patients, because radiation therapy and chemotherapy after tumor surgery will cause damage to female ovarian function, and fertility preservation can be saved after tumor surgery, before radiotherapy and chemotherapy, women's eggs, ovarian tissue or embryos are preserved, and then activated after the patient's body is basically restored, and there are already many such female patients who are happy to become mothers after the condition is stable. For some women to ask whether the egg will also be affected after they have a tumor, Zhao Xiaomiao said that this problem needs to be judged according to the patient's condition, "Some tumors will metastasize with the egg, while some will not, and the medical institution will organize multidisciplinary expert consultation to formulate a detailed plan." Director Zhao Xiaomiao said that according to the mainland law, healthy single women can not do fertility preservation, and the current fertility preservation is mainly to help those who are sick and want to have children, there are strict process regulations. It is reported that for patients of different ages, different fertility preservation methods will be adopted, adult patients can save embryos and eggs, while minor patients whose ovaries have not yet fully developed, such as children with thalassemia, can be fertilized and preserved through frozen ovarian tissue before hematopoietic stem cell transplantation.
Director Zhao Xiaomiao answers questions from fans
Some fans asked, "Why do you still need to check your fallopian tubes when you have normal ovulation?" Zhao Xiaomiao said that some people can ovulate normally, but the time of ovulation is relatively late, resulting in eggs can not be combined with sperm, which may also be a problem with fallopian tubes, in response to "is it life-threatening to become pregnant with tumors at an advanced age?" Zhao Xiaomiao also gave the answer to this question: "This question needs to be judged according to the nature of the tumor, there are many benign tumors, teratomas or bordering tumors, the prognosis is very good, even if it is pregnant with a tumor, it does not matter." And fans are very curious to know", "Will babies born through fertility preservation inherit the mother's disease?" Zhao Xiaomiao said that some tumors caused by genetic mutations, such as malignant breast cancer or ovarian cancer induced by BRCA mutations, may be passed on to children, and if the cancer itself is not hereditary, it will not be inherited.
If you missed the live stream, you can watch the live replay by scanning the QR code below.
Live/Writing: Nandu reporter Zeng Wenqiong
Photograph: Deng Qixiang
Intern: Tang Jingyang
Correspondent: Zhang Lanxi Jin Ting