Hello everyone, I am Dr. Zeng Hongbo of Liu Xiangyuan's fetal protection team. Negative blocking antibodies are one of the immune factors that cause difficulty in conceiving, so are blocking antibodies negative seriously? Here's a chat with you.
Guangzhou Immunotherapy
What is a negative blocking antibody?
Blocking antibody refers to a specific IgG antibody in the serum of normal pregnant women, which has the effect of inhibiting the toxic side reaction of lymphocytes to the embryonic trophoblast and preventing the mother's immune system from attacking the embryo.
If the blocking antibodies in a woman are negative, it may cause infertility or miscarriage after pregnancy. The reasons for the negative occlusive antibodies in women are genetic factors, environmental factors and so on.
Are blocking antibodies negative?
Insufficient production of blocking antibodies, the mother has a strong rejection of the fetus, which can occur in the first trimester of pregnancy and may have repeated spontaneous abortions, and in the third trimester of pregnancy, there may be hypertensive disease of pregnancy and intrauterine growth restriction of the fetus.
Negative blocking antibodies can be treated, and it is necessary to go to a regular specialized hospital to use the husband's lymphocyte active immune method to promote the antibody in the female body to yang, and then continue to prepare for pregnancy after returning to normal.
Blocking antibody negative fetal protection is generally three months after pregnancy, and some women with weak constitutions even keep the fetus for half a year, because negative sealing antibodies can easily lead to miscarriage and fetal intrauterine cessation.
Pregnant women should go to the hospital regularly to observe the development of the fetus. In addition, during pregnancy, pregnant mothers try not to eat spicy and greasy food, but also to maintain a good mood to help the fetus develop smoothly.
How to protect the fetus in the early stages of pregnancy?
The first trimester of pregnancy is about three months before pregnancy, that is, before 12 weeks, which is the most important period of fetal growth and development.
The best way to preserve the fetus is to intervene in a targeted manner based on the individual situation of the pregnant woman. If there are symptoms of threatened miscarriage, fetal protection treatment should be carried out. If it is a normal pregnancy, there is no need to deliberately perform fetal protection therapy.
In the early stages of pregnancy, the four eugenic tests, as well as progesterone, blood hCG, and estradiol are tested. If there is a history of miscarriage with aura, there are more tests to be done, and regularly go to the hospital for re-examination. Try to pay attention not to strenuous exercise, do not overwork, moderate bed rest, fetal development is more smooth.