Single blastocyst transfer
IVF single blastocyst transfer
During the IVF process, some patients are lucky enough to develop multiple blastocysts, but they are difficult in the transplantation process, because doctors usually advocate single blastocyst transplantation. Why is it recommended to grow multiple blastocysts but only one blastocyst is transplanted? Let's talk about the reasons for choosing single blastocyst transplantation.
Blastocyst transfer is more "quality" than "quantity"
Blastocysts are a phase of embryonic development, and blastocyst culture refers to the culture of embryos up to 5 to 7 days in IVF treatment.
Blastocyst culture requirements are high, not all embryos at the embryo of the cleft stage can be cultured into blastocysts, and the chance of good quality embryos developing into blastocysts is relatively large. Therefore, the process of blastocyst culture is also the process of survival of the fittest, which can screen out embryos with higher development and planting potential, and the probability of successful pregnancy after transfer to the mother is relatively large.
Single blastocyst transfer reduces the probability of multiple pregnancies
Single blastocyst transfer is a clinically effective way to reduce multiple pregnancies.
Multiple pregnancies tend to lead to adverse pregnancy outcomes such as miscarriage, preterm birth, intrauterine growth retardation, and gestational hypertension syndrome, and are seen as serious complications of assisted reproductive technology rather than as successful fertility outcomes.
Traditional IVF treatment usually selects the transfer of 2-3 fissure embryos according to age, which increases the clinical pregnancy rate and increases the risk of multiple pregnancies and ovarian hyperstimulation syndrome. Single blastocyst transfer effectively avoids multiple pregnancies by reducing the number of transferred embryos.
Single blastocyst transplantation increases cumulative pregnancy rates
Studies have confirmed that the clinical pregnancy rate of transferring a single blastocyst is significantly higher than that of transferring a single cleft embryo.
Relevant research reports pointed out that the comparison between single blastocyst and two blastocyst implantation in 40-44-year-old women showed that the pregnancy rate and live birth rate of single blastocyst implantation were not worse than those of two implants.
Numerous studies have found that blastocyst transplantation has a higher planting rate, and choosing single blastocyst transplantation can not only improve the cumulative pregnancy rate, but also does not reduce the pregnancy rate of each transplant cycle, but also reduces the rate of multiple pregnancies and reduces the risk of ovarian overstimulation.
Because the implantation rate of embryo transfer is not as good as that of blastocysts, it is often necessary to transfer two to improve the pregnancy rate, and the blastocysts are usually transferred to a single blastocyst due to the higher probability of implantation, and single blastocyst transfer can not only guarantee the pregnancy rate, but also reduce the risk of multiple pregnancies, ectopic pregnancy, etc., so single blastocyst transfer is a better choice.