Many women during IVF, at the very beginning of the doctor to take folic acid, AA69 fertility wants to ask you, do you know why?
Folic acid supplementation should be started 3 months before the decision to become pregnant, as it usually takes at least 3 consecutive oral doses of folic acid for at least 3 months to bring the concentration of folate in the mother's blood to a level that is effective in preventing neural tube defects.
It is a little late to wait until pregnant to supplement folic acid. Because the neural tubes of the fetus develop and close relatively early, the whole process is completed in the 22-28 days of the embryo. At this time, many people have not yet realized that they are pregnant, or have just found out that they are pregnant, it is useless to temporarily hold the Buddha's feet, and the concentration of folic acid is not up to the level of effective prevention of neural tube defects.
For the prevention of neural tube defects, folic acid supplementation during pregnancy preparation is important, but if it is an unintended pregnancy, there is no time to prepare. The development of the fetal neural tube is completed in the early pregnancy, so the mission of folic acid to prevent neural tube defects is also ended in the early pregnancy, and at the end of the 3rd month of pregnancy, oral folic acid can be stopped.
Folic acid is widely present in a variety of animal and plant foods, animals, such as eggs, such as chickens, ducks, animal meat, pigs, cattle, sheep and liver and kidneys, vegetables, such as spinach, rapeseed, greens, lettuce, lentils, cauliflower, pumpkin, carrots, mushrooms, etc.; beans and nuts, such as soybeans, soy products, almonds, walnuts, chestnuts, pine nuts, cashews, etc.; grains, such as barley, brown rice, whole wheat flour, etc.; fruits, such as kiwifruit, strawberries, peaches, hawthorns, pomegranates, grapes, oranges, cherries , bananas, lemons, plums, apricots, pears, walnuts, apples, etc.
However, the loss rate of folic acid in food after cooking and processing can reach 50%-90%. About 3/4 of the folic acid in mixed diets is present in the form of a combination of glutamate and is not easily absorbed and utilized.
Since the bioavailability of folate in food is only 50%, and the bioavailability of folic acid supplements when mixed with diet is 85%, it is 1.7 times higher than the use of folic acid derived from food alone, which is why doctors tell you to take folic acid during the test tube preparation stage and for a period of time after the test tube.