Singer Justin Bieber once said in the documentary "Seasons" that he maintains his youthful state by "inhaling hyperbaric oxygen".
Then the civilian high-pressure chamber, known as the "time machine", unexpectedly became popular with the ability to become younger. Recently, it has also been endorsed by Israeli scientists: after 90 days of hyperbaric oxygen inhalation, aging cells are reduced by 37%, which is theoretically equivalent to returning to 20 years old.
1.90 days back to 20 years old, what exactly is high-pressure oxygen?
Hyperbaric oxygen therapy refers to the provision of pure oxygen respiration in an environment exceeding one atmospheric pressure. At first, it was mostly used by professional institutions to treat carbon monoxide poisoning and cerebral blood supply. The above-mentioned civilian hyperbaric oxygen, which has the scientific endorsement of Israeli scientists, is extended on this basis, the air pressure is relatively small, and the main can be "reverse growth".
Hyperbaric oxygen is the process of dissolving oxygen in the bloodstream and bringing it throughout the body by means of high pressure. Some capillaries are too narrow, and blood cells cannot pass through the tissue, and can only rely on oxygen in the blood to provide "nutrients". Research released by Kassandra, a professor in the Department of Molecular and Cellular Biology at the NIH (National Institutes of Health), also found that repeated exposure to hyperoxic environments can upregulate oxidant genes and produce scavengers, which can improve the body's antioxidant properties. Based on this, it may be possible to achieve a state of "reverse growth".
To further confirm its capabilities, the above-mentioned research team, led by Shai Efrati, a professor at Tel Aviv University School of Medicine in Israel, selected 35 healthy elderly people over the age of 65 as experimental samples. The subjects were placed in an oxygen chamber and inhaled oxygen for an hour and a half a day for 90 days.
It was then found that the aging cells in the subjects were reduced by 37%, and the telomeres were elongated by 20%, and the longest reached 52.5%. Theoretically, the subject's bodily functions are equivalent to returning to the level of 20 years old.
When scientists published the results of this study in the journal Aging, it caused an uproar, and the number of customer consultations for the "o2ark hyperbaric oxygen chamber" directly increased by 15 times. Professor Efrati, who led the experiment, also believes that through this study, the elongation of telomeres provides a new argument for the scientific community that at the basic level of cell biology, aging may be reversible.
2. Mechanism behind youthfulness: Telomeres are elongated after oxygen inhalation
In experiments, telomeres were elongated by 20% due to oxygen inhalation, which was particularly noticeable. Telomeres are at both ends of DNA and are protective shells of chromosomes that ensure the integrity of DNA and genetic information.
In 2009, Jack W. et al. of Harvard Medical School won the Nobel Prize that year for discovering the principle of telomeres and telomerase protecting chromosomes. Each time a chromosome is copied, telomere loss is caused. When telomeres are "lost", cells die because they cannot divide.
As a result, telomeres become "remote control" that controls the process of cell aging and death, and the shortening of telomeres is recognized as a biological marker of cell aging.
In recent years, with the further derivation of biotechnology, the relationship between telomeres and elderly has been further explored by the academic community. The Amano team at Baylor School of Medicine, published in Cell Metabolism, first found that telomere lengths can be lengthened by supplementing with a single coenzyme.
Since then, the Tsinghua-Peking University Joint Life Center, Sichuan University School of Medicine, and Keio University School of Medicine in Japan have successively discovered a positive relationship between coenzymes and telomeres, and have great potential in the intervention of the old face. Then it gave birth to the "Palovi" dietary supplement, which captured the public's vision.
In addition to the endless emergence of scientific research endorsements, celebrity endorsements are not uncommon. For example, Li Ka-shing has also been taken for many years, and even spent $25 million to invest in "Palovis" substances. Recently circulated in the photo with the younger 30-year-old girlfriend, it is more mental, do not know whether it is related to this kind of substance.
The mechanism behind the inhalation of hyperbaric oxygen back to the age of 20 is precisely due to the fact that the telomeres at the biological level are shortened by 20%. Professor Efrati said that the rate of aging of hyperbaric oxygen injection interventions far exceeds that of any currently available intervention, which can open a window for further exploration of the potential of hyperbaric oxygen "reverse growth".
3. Hyperbaric oxygen therapy is still young, but the future can be expected
The exploration of hyperbaric oxygen-related scientific research has been deepening, and people are gradually looking forward to the possibility of whether they can "recharge" their lives. Professor David, one of the leading figures in the biotech industry, has also "helped" him, and he has published 7 anti-aging secret recipes on social media, and hyperbaric oxygen therapy is listed.
Although hyperbaric oxygen therapy is favored by most people, its drawbacks cannot be ignored.
The first is the current scientific research on hyperbaric oxygen therapy, the samples are small, and there is no placebo control. Although there are relatively good results in 90 days, it is still unknown in the long run. The coenzyme substances mentioned above have more than 1,000 papers in journals such as cell and nature, and there are countless Lin bed experiments.
The second is the price point. The "o2ark" hyperbaric oxygen chamber on the market, the official price ranges from 300,000 to 1 million, landing in the Shanghai experience store, a single experience also needs 3 digits, the price is generally higher. Compared with the mature "Palovir" and other dietary agents, the official pricing of Pingdong is 3 digits, and the public acceptance is higher. It can be seen that hyperbaric oxygen therapy is still young, and it is still time to consider whether to draw a relatively complete conclusion through existing research.
But for now, hyperbaric oxygen therapy is moving in a bright direction, and the future is still worth looking forward to.